ME02343B - Derivati alfa-aminoamida korisni u liječenju kognitivnih poremećaja - Google Patents

Derivati alfa-aminoamida korisni u liječenju kognitivnih poremećaja

Info

Publication number
ME02343B
ME02343B MEP-2016-23A MEP2316A ME02343B ME 02343 B ME02343 B ME 02343B ME P2316 A MEP2316 A ME P2316A ME 02343 B ME02343 B ME 02343B
Authority
ME
Montenegro
Prior art keywords
alpha
treatment
cognitive disorders
derivatives useful
aminoamide derivatives
Prior art date
Application number
MEP-2016-23A
Other languages
English (en)
Inventor
Patricia Salvati
Stefano Rossetti
Luca Benatti
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of ME02343B publication Critical patent/ME02343B/me

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MEP-2016-23A 2006-06-15 2007-06-13 Derivati alfa-aminoamida korisni u liječenju kognitivnih poremećaja ME02343B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06012352A EP1870097A1 (en) 2006-06-15 2006-06-15 Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
PCT/EP2007/005197 WO2007144153A2 (en) 2006-06-15 2007-06-13 Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
EP07725989.3A EP2029130B1 (en) 2006-06-15 2007-06-13 Alpha-aminoamide derivatives useful in the treatment of cognitive disorders

Publications (1)

Publication Number Publication Date
ME02343B true ME02343B (me) 2016-06-20

Family

ID=37103353

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2016-23A ME02343B (me) 2006-06-15 2007-06-13 Derivati alfa-aminoamida korisni u liječenju kognitivnih poremećaja

Country Status (26)

Country Link
US (1) US8741957B2 (me)
EP (4) EP1870097A1 (me)
JP (2) JP2009539908A (me)
KR (1) KR20090018817A (me)
CN (2) CN101466366A (me)
AR (1) AR061505A1 (me)
AU (1) AU2007260239B2 (me)
BR (1) BRPI0712994A2 (me)
CA (1) CA2655243C (me)
CY (1) CY1116699T1 (me)
DK (1) DK2029130T3 (me)
EA (1) EA018006B1 (me)
ES (1) ES2549113T3 (me)
HK (1) HK1170429A1 (me)
HR (1) HRP20151026T1 (me)
HU (1) HUE026484T2 (me)
IL (1) IL195906A (me)
ME (1) ME02343B (me)
MX (1) MX2008016017A (me)
NZ (1) NZ573565A (me)
PL (1) PL2029130T3 (me)
PT (1) PT2029130E (me)
RS (1) RS54324B1 (me)
SI (1) SI2029130T1 (me)
TW (1) TWI494293B (me)
WO (1) WO2007144153A2 (me)

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DK1658062T3 (da) * 2003-08-25 2010-05-31 Newron Pharm Spa Alfa-aminoamid-derivater anvendelige som anti-inflammatoriske midler
EP1870097A1 (en) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
BRPI0712936B8 (pt) 2006-06-19 2021-05-25 Newron Pharm Spa processo para a produção de 2-[4-(3- e 2-fluorbenziloxi)benzila-mino]propanamidas
CN101687773B (zh) 2007-06-15 2014-07-30 纽朗制药有限公司 取代的2-[2-(苯基)乙氨基]烷酰胺衍生物及其作为钠和/或钙通道调节剂的应用
EA019529B1 (ru) * 2007-12-19 2014-04-30 Ньюрон Фармасьютикалс С.П.А. Альфа-аминоамидные производные, применяемые в лечении психиатрических расстройств
EP2314569A1 (en) 2009-10-22 2011-04-27 Merck Patent GmbH Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
WO2011055383A2 (en) 2009-11-06 2011-05-12 Lyka Labs Limited Intranasal delivery to improve the performance of children suffering from dyslexia
US8255838B2 (en) * 2010-01-15 2012-08-28 Synopsys, Inc. Etch-aware OPC model calibration by using an etch bias filter
WO2011098456A1 (en) * 2010-02-09 2011-08-18 Merck Serono S.A. Safinamide in the treatment of dyskinesia
KR101851118B1 (ko) 2010-04-27 2018-04-23 뉴론 파마슈티칼즈 에스. 피. 에이. 랄핀아미드 메탄설포네이트 염들 또는 이들의 r―에난티오머들의 제조 방법
WO2013139861A1 (en) 2012-03-20 2013-09-26 Luc Montagnier Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders
ES2426539B1 (es) 2012-04-18 2014-09-09 Dr Healthcare España, S. L. Uso de la diaminooxidasa para el tratamiento o la prevención del trastorno por deficit de atencion con hiperactividad (adhd)
KR101420218B1 (ko) * 2012-06-13 2014-07-17 이우일 생리적안정도 측정 시스템 및 그 방법
CN104546747A (zh) * 2014-11-20 2015-04-29 美吉斯制药(厦门)有限公司 一种含有甲磺酸沙芬酰胺的药物组合物及其制备方法
CN105456214A (zh) * 2015-12-30 2016-04-06 蔡惠文 甲磺酸沙芬酰胺片
KR101970099B1 (ko) * 2018-02-07 2019-04-17 한국과학기술연구원 척수 손상의 예방 및 치료용 조성물
KR102005019B1 (ko) * 2018-04-04 2019-07-31 한국과학기술연구원 뇌졸중의 예방 및 치료용 조성물
AU2019271189A1 (en) * 2018-05-15 2021-01-07 Lloyd Hung Loi TRAN Therapeutic agent composition and method of use, for treatment of mild cognitive impairment, depression, and psychological disorders
WO2020234275A1 (en) * 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's diseases

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GB1140748A (en) 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US3795739A (en) 1972-02-14 1974-03-05 Hoffmann La Roche Treatment of parkinson disease
US4049663A (en) 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
FR2480747A1 (fr) 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
EP0331620B1 (de) 1988-03-01 1993-08-11 Birkmayer, Walther, Prof. Dr. Mittel zur Behandlung des Parkinson-Syndroms
IL94466A (en) 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
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Also Published As

Publication number Publication date
CN102512406B (zh) 2015-01-07
HK1170429A1 (en) 2013-03-01
NZ573565A (en) 2013-01-25
EA018006B1 (ru) 2013-04-30
EP2029130A2 (en) 2009-03-04
WO2007144153A2 (en) 2007-12-21
PL2029130T3 (pl) 2016-01-29
EA200802306A1 (ru) 2009-06-30
CN102512406A (zh) 2012-06-27
IL195906A (en) 2016-02-29
EP2029130B1 (en) 2015-08-19
JP2009539908A (ja) 2009-11-19
AR061505A1 (es) 2008-09-03
MX2008016017A (es) 2009-01-16
JP2013155186A (ja) 2013-08-15
CN101466366A (zh) 2009-06-24
PT2029130E (pt) 2015-10-28
CA2655243C (en) 2015-06-02
HUE026484T2 (en) 2016-06-28
EP2977046A1 (en) 2016-01-27
DK2029130T3 (en) 2015-11-16
HRP20151026T1 (hr) 2015-10-23
TW200808696A (en) 2008-02-16
WO2007144153A3 (en) 2008-03-13
US20100016437A1 (en) 2010-01-21
AU2007260239B2 (en) 2012-08-30
KR20090018817A (ko) 2009-02-23
SI2029130T1 (sl) 2015-11-30
TWI494293B (zh) 2015-08-01
CY1116699T1 (el) 2017-03-15
AU2007260239A1 (en) 2007-12-21
ES2549113T3 (es) 2015-10-23
RS54324B1 (en) 2016-02-29
BRPI0712994A2 (pt) 2012-03-27
CA2655243A1 (en) 2007-12-21
EP2343064A1 (en) 2011-07-13
US8741957B2 (en) 2014-06-03
EP1870097A1 (en) 2007-12-26
JP6119068B2 (ja) 2017-04-26
IL195906A0 (en) 2009-09-01

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