EA200801302A1 - Композиции и способы лечения нарушений цнс - Google Patents

Композиции и способы лечения нарушений цнс

Info

Publication number
EA200801302A1
EA200801302A1 EA200801302A EA200801302A EA200801302A1 EA 200801302 A1 EA200801302 A1 EA 200801302A1 EA 200801302 A EA200801302 A EA 200801302A EA 200801302 A EA200801302 A EA 200801302A EA 200801302 A1 EA200801302 A1 EA 200801302A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
compositions
methods
cns disorders
thienopyridinone
Prior art date
Application number
EA200801302A
Other languages
English (en)
Inventor
Дэйл С. Даноа
Орен М. Беккер
Сильвия Нойман
Прадиумна Моханти
Донли Чень
Мерседес Лобера
Лоуренс Ву
Яэл Марантц
Боаз Инбал
Александр Хейфетц
Шай Бар-Хаим
Шарон Шачам
Original Assignee
Эпикс Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эпикс Фармасьютикалз, Инк. filed Critical Эпикс Фармасьютикалз, Инк.
Publication of EA200801302A1 publication Critical patent/EA200801302A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение в общем относится к тиенопиридиноновым модуляторам рецепторов 5-НТи в частности к применению этих соединений и их фармацевтических композиций, например, в лечении, модулировании и/или предотвращении физиологических состояний, связанных с действием серотонина, таких как, например, лечение болезни Альцгеймера, когнитивных расстройств, депрессии и беспокойства.
EA200801302A 2005-11-10 2006-11-06 Композиции и способы лечения нарушений цнс EA200801302A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/271,019 US7598265B2 (en) 2004-09-30 2005-11-10 Compositions and methods for treating CNS disorders
PCT/US2006/043140 WO2007058805A2 (en) 2005-11-10 2006-11-06 Compositions and methods for treating cns disorders

Publications (1)

Publication Number Publication Date
EA200801302A1 true EA200801302A1 (ru) 2009-02-27

Family

ID=37946751

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801302A EA200801302A1 (ru) 2005-11-10 2006-11-06 Композиции и способы лечения нарушений цнс

Country Status (17)

Country Link
US (2) US7598265B2 (ru)
EP (1) EP1959954A2 (ru)
JP (1) JP2009515877A (ru)
KR (1) KR20080067001A (ru)
CN (1) CN101340908A (ru)
AR (1) AR057887A1 (ru)
AU (1) AU2006315854A1 (ru)
BR (1) BRPI0618493A2 (ru)
CA (1) CA2629312C (ru)
CR (1) CR10062A (ru)
EA (1) EA200801302A1 (ru)
IL (1) IL191168A0 (ru)
MA (1) MA30037B1 (ru)
NO (1) NO20082679L (ru)
TW (1) TW200735868A (ru)
WO (1) WO2007058805A2 (ru)
ZA (1) ZA200804951B (ru)

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US20230139125A1 (en) * 2021-02-04 2023-05-04 Richard Natrillo Dietary supplement for improving brain performance

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Also Published As

Publication number Publication date
NO20082679L (no) 2008-06-10
AR057887A1 (es) 2007-12-26
AU2006315854A1 (en) 2007-05-24
US20060234998A1 (en) 2006-10-19
CA2629312C (en) 2014-08-12
WO2007058805A2 (en) 2007-05-24
US7598265B2 (en) 2009-10-06
CR10062A (es) 2009-05-14
JP2009515877A (ja) 2009-04-16
CA2629312A1 (en) 2007-05-24
US20110195953A1 (en) 2011-08-11
TW200735868A (en) 2007-10-01
KR20080067001A (ko) 2008-07-17
CN101340908A (zh) 2009-01-07
BRPI0618493A2 (pt) 2011-08-30
MA30037B1 (fr) 2008-12-01
WO2007058805A3 (en) 2007-10-04
EP1959954A2 (en) 2008-08-27
ZA200804951B (en) 2009-04-29
IL191168A0 (en) 2008-12-29

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