CY1115606T1 - Ετεροκυκλικες ενωσεις, μεθοδοι κατασκευης αυτων και χρηση αυτων στη θεραπεια - Google Patents
Ετεροκυκλικες ενωσεις, μεθοδοι κατασκευης αυτων και χρηση αυτων στη θεραπειαInfo
- Publication number
- CY1115606T1 CY1115606T1 CY20141100786T CY141100786T CY1115606T1 CY 1115606 T1 CY1115606 T1 CY 1115606T1 CY 20141100786 T CY20141100786 T CY 20141100786T CY 141100786 T CY141100786 T CY 141100786T CY 1115606 T1 CY1115606 T1 CY 1115606T1
- Authority
- CY
- Cyprus
- Prior art keywords
- therapy
- construction
- methods
- heterocyclic compounds
- cycloalkyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Medicinal Preparation (AREA)
Abstract
Εν μέρει, η παρούσα εφεύρεση κατευθύνεται σε αντιβακτηριακές ενώσεις του τύπου (Ι) όπου το Α είναι δικυκλικός ετεροαρύλ δακτύλιος ή τρικυκλικός δακτύλιος και το R2 είναι ετεροκυκλικό υπόλειμμα, το L είναι δεσμός ή το L είναι αλκύλ, αλκενύλ ή κυκλοαλκύλ.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43140602P | 2002-12-06 | 2002-12-06 | |
US46558303P | 2003-04-25 | 2003-04-25 | |
EP03796699.1A EP1575951B1 (en) | 2002-12-06 | 2003-12-05 | Heterocyclic compounds, methods of making them and their use in therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1115606T1 true CY1115606T1 (el) | 2017-01-04 |
Family
ID=32511562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20141100786T CY1115606T1 (el) | 2002-12-06 | 2014-09-25 | Ετεροκυκλικες ενωσεις, μεθοδοι κατασκευης αυτων και χρηση αυτων στη θεραπεια |
Country Status (11)
Country | Link |
---|---|
US (2) | US7790709B2 (el) |
EP (1) | EP1575951B1 (el) |
JP (2) | JP4859460B2 (el) |
AU (1) | AU2003298937A1 (el) |
CA (1) | CA2508792C (el) |
CY (1) | CY1115606T1 (el) |
DK (1) | DK1575951T3 (el) |
ES (1) | ES2518316T3 (el) |
PT (1) | PT1575951E (el) |
SI (1) | SI1575951T1 (el) |
WO (1) | WO2004052890A1 (el) |
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CA2508792C (en) | 2002-12-06 | 2013-02-05 | Affinium Pharmaceuticals, Inc. | Heterocyclic compounds, methods of making them and their use in therapy |
EP1608377B1 (en) * | 2003-03-17 | 2008-10-01 | Affinium Pharmaceuticals, Inc. | Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics |
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US20090156578A1 (en) * | 2005-12-05 | 2009-06-18 | PAULS Henry | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents |
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-
2003
- 2003-12-05 CA CA2508792A patent/CA2508792C/en not_active Expired - Fee Related
- 2003-12-05 EP EP03796699.1A patent/EP1575951B1/en not_active Expired - Lifetime
- 2003-12-05 DK DK03796699.1T patent/DK1575951T3/da active
- 2003-12-05 SI SI200332388T patent/SI1575951T1/sl unknown
- 2003-12-05 AU AU2003298937A patent/AU2003298937A1/en not_active Abandoned
- 2003-12-05 PT PT37966991T patent/PT1575951E/pt unknown
- 2003-12-05 ES ES03796699.1T patent/ES2518316T3/es not_active Expired - Lifetime
- 2003-12-05 JP JP2005508475A patent/JP4859460B2/ja not_active Expired - Fee Related
- 2003-12-05 US US10/537,747 patent/US7790709B2/en not_active Expired - Lifetime
- 2003-12-05 WO PCT/US2003/038706 patent/WO2004052890A1/en active Application Filing
-
2010
- 2010-07-27 US US12/844,403 patent/US20110124633A1/en not_active Abandoned
-
2011
- 2011-06-30 JP JP2011145487A patent/JP2012006927A/ja active Pending
-
2014
- 2014-09-25 CY CY20141100786T patent/CY1115606T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
SI1575951T1 (sl) | 2014-10-30 |
JP2012006927A (ja) | 2012-01-12 |
US20110124633A1 (en) | 2011-05-26 |
CA2508792A1 (en) | 2004-06-24 |
ES2518316T3 (es) | 2014-11-05 |
DK1575951T3 (da) | 2014-09-15 |
WO2004052890A1 (en) | 2004-06-24 |
CA2508792C (en) | 2013-02-05 |
AU2003298937A1 (en) | 2004-06-30 |
EP1575951A1 (en) | 2005-09-21 |
JP2006513262A (ja) | 2006-04-20 |
JP4859460B2 (ja) | 2012-01-25 |
EP1575951B1 (en) | 2014-06-25 |
US20060183908A1 (en) | 2006-08-17 |
US7790709B2 (en) | 2010-09-07 |
PT1575951E (pt) | 2014-09-15 |
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