CY1114463T1 - Κλωνος κυτταρου που παραγει fsh - Google Patents

Κλωνος κυτταρου που παραγει fsh

Info

Publication number
CY1114463T1
CY1114463T1 CY20131100874T CY131100874T CY1114463T1 CY 1114463 T1 CY1114463 T1 CY 1114463T1 CY 20131100874 T CY20131100874 T CY 20131100874T CY 131100874 T CY131100874 T CY 131100874T CY 1114463 T1 CY1114463 T1 CY 1114463T1
Authority
CY
Cyprus
Prior art keywords
nucleic acid
cell
present
recombinant
relates
Prior art date
Application number
CY20131100874T
Other languages
Greek (el)
English (en)
Inventor
Stefan Arnold
Nanni Jelinek
Original Assignee
Biogenerix Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenerix Ag filed Critical Biogenerix Ag
Publication of CY1114463T1 publication Critical patent/CY1114463T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CY20131100874T 2007-06-28 2013-10-09 Κλωνος κυτταρου που παραγει fsh CY1114463T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07111257 2007-06-28
EP08774439.7A EP2170942B1 (en) 2007-06-28 2008-06-27 Fsh producing cell clone

Publications (1)

Publication Number Publication Date
CY1114463T1 true CY1114463T1 (el) 2016-10-05

Family

ID=39745099

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100874T CY1114463T1 (el) 2007-06-28 2013-10-09 Κλωνος κυτταρου που παραγει fsh

Country Status (23)

Country Link
US (1) US8318457B2 (https=)
EP (2) EP2170942B1 (https=)
JP (1) JP5570980B2 (https=)
KR (1) KR101522217B1 (https=)
CN (1) CN101720332B (https=)
AU (1) AU2008267138B9 (https=)
BR (1) BRPI0813913B1 (https=)
CA (1) CA2690844C (https=)
CY (1) CY1114463T1 (https=)
DK (1) DK2170942T3 (https=)
EA (1) EA022993B1 (https=)
ES (1) ES2432183T3 (https=)
HR (1) HRP20130921T1 (https=)
IL (1) IL202280A (https=)
MX (1) MX2010000385A (https=)
NZ (1) NZ581702A (https=)
PL (1) PL2170942T3 (https=)
PT (1) PT2170942E (https=)
RS (1) RS52976B (https=)
SI (1) SI2170942T1 (https=)
UA (1) UA103598C2 (https=)
WO (1) WO2009000913A1 (https=)
ZA (1) ZA200908168B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ586588A (en) 2008-02-08 2012-10-26 Biogenerix Ag Formulation of ( follice stimulating hormone) fsh and varients with benzalkonium chloride and benzyl alcohol
JP5845170B2 (ja) 2009-04-01 2016-01-20 ラティオファーム ゲーエムベーハー 組換えｆｓｈを精製する方法
EP2325194A1 (en) 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
US9657310B2 (en) * 2012-04-27 2017-05-23 Jcr Pharmaceuticals Co., Ltd. Expression vector
CN103539861B (zh) * 2013-11-01 2015-02-18 广州联康生物科技有限公司 长效重组人促卵泡激素融合蛋白
CN103554269B (zh) * 2013-11-01 2015-02-11 广州联康生物科技有限公司 重组猪促卵泡激素融合蛋白
CN103539860B (zh) * 2013-11-01 2014-12-03 广州优联康医药科技有限公司 一种长效重组人促卵泡激素融合蛋白
CN105462909B (zh) * 2015-12-31 2019-09-27 哈药集团技术中心 一种高效表达人促卵泡激素的cho细胞的培养方法
CN107460206B (zh) * 2017-09-11 2020-05-01 深圳市深研生物科技有限公司 人fsh的重组表达载体、重组细胞株及重组人fsh的制备方法
CN111349154A (zh) * 2018-12-21 2020-06-30 江苏众红生物工程创药研究院有限公司 一种重组人促卵泡激素及其制备方法和药物应用
CN110812366B (zh) * 2019-11-18 2023-11-17 珠海丽凡达生物技术有限公司 一种可用于激素补充的mRNA药物及其制备方法
CN120519466A (zh) * 2025-07-23 2025-08-22 苏州晟济药业有限公司 卵泡刺激素表达系统

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923805A (en) 1983-11-02 1990-05-08 Integrated Genetics, Inc. Fsh
IT1206302B (it) 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
CA2018676C (en) 1989-06-20 2003-05-06 Christie A. Kelton Novel heteropolymeric protein production methods
US6183987B1 (en) 1995-02-17 2001-02-06 Stichting Institut Voor Dierhouderij En Diergezonheld Production of biologically active recombinant bovine follicle stimulation hormone (rec bFSH) in the baculovirus expression system
IL122732A0 (en) 1997-01-15 1998-08-16 Akzo Nobel Nv Liquid gonadotropin-containing formulation its preparation and a device containing same
IL140984A0 (en) 1998-07-23 2002-02-10 Lilly Co Eli Fsh and fsh variant formulations, products and methods
BRPI0010677B8 (pt) 1999-04-16 2021-05-25 Inst Massone S A processo de purificação de gonadotropinas urinárias humanas a partir de gonadotropinas brutas.
US20020127652A1 (en) 2000-02-11 2002-09-12 Schambye Hans Thalsgard Follicle stimulating hormones
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones
JP2006500927A (ja) * 2002-09-13 2006-01-12 ザ・ユニバーシティ・オブ・クイーンズランド コドン翻訳効率に基づく遺伝子発現系
KR100533794B1 (ko) * 2003-10-02 2005-12-07 주식회사 프로젠 인간 난포자극 호르몬을 대량으로 생산하는 방법
EP1697412B1 (en) 2003-12-22 2009-10-21 Ares Trading S.A. Method for purifying fsh
DE602005009856D1 (de) 2004-11-09 2008-10-30 Ares Trading Sa Verfahren zur reinigung von fsh
TWI369401B (en) * 2005-07-05 2012-08-01 Ares Trading Sa Serum-free culture medium for the production of recombinant gonadotropins
US20070281883A1 (en) 2006-06-05 2007-12-06 Hanna Rosenfeld Development of follicle stimulating hormone agonists and antagonists in fish

Also Published As

Publication number Publication date
PT2170942E (pt) 2013-10-22
EP2492280A1 (en) 2012-08-29
CN101720332A (zh) 2010-06-02
IL202280A (en) 2014-12-31
KR101522217B1 (ko) 2015-05-21
DK2170942T3 (da) 2013-11-04
UA103598C2 (uk) 2013-11-11
ZA200908168B (en) 2010-07-28
KR20100051632A (ko) 2010-05-17
PL2170942T3 (pl) 2013-12-31
EP2170942A1 (en) 2010-04-07
BRPI0813913B1 (pt) 2022-04-19
HK1140782A1 (en) 2010-10-22
BRPI0813913A2 (pt) 2014-12-30
SI2170942T1 (sl) 2013-12-31
CA2690844C (en) 2016-05-17
EA201070071A1 (ru) 2010-10-29
CN101720332B (zh) 2014-08-13
RS52976B (sr) 2014-02-28
HRP20130921T1 (hr) 2013-11-08
MX2010000385A (es) 2010-03-29
US8318457B2 (en) 2012-11-27
JP2010531148A (ja) 2010-09-24
CA2690844A1 (en) 2008-12-31
JP5570980B2 (ja) 2014-08-13
AU2008267138A1 (en) 2008-12-31
EA022993B1 (ru) 2016-04-29
IL202280A0 (en) 2010-06-16
NZ581702A (en) 2011-10-28
EP2170942B1 (en) 2013-07-31
US20120034655A1 (en) 2012-02-09
WO2009000913A1 (en) 2008-12-31
BRPI0813913A8 (pt) 2018-02-14
AU2008267138B9 (en) 2014-06-05
AU2008267138B2 (en) 2014-01-16
ES2432183T3 (es) 2013-12-02

Similar Documents

Publication Publication Date Title
CY1114463T1 (el) Κλωνος κυτταρου που παραγει fsh
BRPI1007214A2 (pt) adaptador para sequenciar ácidos nucleicos, par de adaptadores, kit, construto de ácido nucleico, e, métodos para preparar um adaptador, um construto de ácido nucleico, e um construto de dequência, e para sequenciar ácido nucleico de fita dupla.
ATE481483T1 (de) Verfahren zur herstellung eines rekombinanten polyklonalen proteins
MX2021000209A (es) Metodos y productos para transfeccion de celulas.
EA201390689A1 (ru) Консенсусные антигены простаты, молекула нуклеиновой кислоты, кодирующая их, и вакцина, и использование, включающее их
PH12020551039A1 (en) Non-viral dna vectors and uses thereof for antibody and fusion protein production
MX2022002834A (es) Polipeptidos con actividad beta-glucanasa y polinucleotidos que los codifican.
UY31875A (es) Novedosos genes involucrados en la biosíntesis
MX2020006065A (es) Metodos y productos para la produccion y administracion de acido nucleico.
BR112012016318A2 (pt) "alfa-amilase isolada, composição, método pra produzir amido liquefeito, processo para sintetizar um produto de fermentação, sequência de acidos nucleicos, célula hospedeira, e, método para preparar uma alfa-amilase."
NO20076087L (no) Serum-fri stabil transfeksjon og fremstilling av rekombinante humane proteiner i humane cellelinjer
BR112014008694A2 (pt) moléculas de ácido nucleico policistrônico recombinante
MX348360B (es) Anticuerpo biespecifico psmaxcd3 de simple cadena especifico de especies cruzadas.
MX363017B (es) Métodos y productos para la expresión de proteínas en células.
JP2015525065A5 (https=)
EA201170506A1 (ru) Генная терапия порфобилиногендезаминазой
MX2021000421A (es) Métodos y composiciones que usan células dendríticas recombinantes para el tratamiento del cáncer.
ATE535605T1 (de) Autoinduzierbarer natriumphosphat-symporter- promotor aus pichia pastoris und verfahren zur herstellung von rekombinantem protein unter verwendung davon
EA201301143A1 (ru) ПРОДУЦЕНТ ЭПИДЕРМАЛЬНОГО ФАКТОРА РОСТА ЧЕЛОВЕКА (рчЭФР)
CN101934069A (zh) 脑红蛋白在促进神经元突起生长中的应用
AU2016216577A1 (en) Codon optimized IL-15 and IL-15R-alpha genes for expression in mammalian cells
EA200702009A1 (ru) Усовершенствованный способ экспрессирующего клонирования в клетке-хозяине
MX2026000656A (es) Molecula recombinante de aminoacidos, celulas hospedadoras para la produccion de l-arginina y metodos para la produccion de l-arginina utilizando las mismas
AR119983A1 (es) POLIPÉPTIDOS CON ACTIVIDAD b-GLUCANASA Y POLINUCLEÓTIDOS QUE LOS CODIFICAN
Schiera et al. Melanoma cells release extracellular vesicle which contain H1° linker histone as well as RNA-binding proteins which bind to the H1° mRNA