PT2170942E - Clone celular produtor de fsh - Google Patents

Clone celular produtor de fsh

Info

Publication number
PT2170942E
PT2170942E PT87744397T PT08774439T PT2170942E PT 2170942 E PT2170942 E PT 2170942E PT 87744397 T PT87744397 T PT 87744397T PT 08774439 T PT08774439 T PT 08774439T PT 2170942 E PT2170942 E PT 2170942E
Authority
PT
Portugal
Prior art keywords
nucleic acid
present
fsh
recombinant
relates
Prior art date
Application number
PT87744397T
Other languages
English (en)
Portuguese (pt)
Inventor
Stefan Arnold
Nanni Jelinek
Original Assignee
Biogenerix Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenerix Ag filed Critical Biogenerix Ag
Publication of PT2170942E publication Critical patent/PT2170942E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PT87744397T 2007-06-28 2008-06-27 Clone celular produtor de fsh PT2170942E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07111257 2007-06-28

Publications (1)

Publication Number Publication Date
PT2170942E true PT2170942E (pt) 2013-10-22

Family

ID=39745099

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87744397T PT2170942E (pt) 2007-06-28 2008-06-27 Clone celular produtor de fsh

Country Status (23)

Country Link
US (1) US8318457B2 (https=)
EP (2) EP2170942B1 (https=)
JP (1) JP5570980B2 (https=)
KR (1) KR101522217B1 (https=)
CN (1) CN101720332B (https=)
AU (1) AU2008267138B9 (https=)
BR (1) BRPI0813913B1 (https=)
CA (1) CA2690844C (https=)
CY (1) CY1114463T1 (https=)
DK (1) DK2170942T3 (https=)
EA (1) EA022993B1 (https=)
ES (1) ES2432183T3 (https=)
HR (1) HRP20130921T1 (https=)
IL (1) IL202280A (https=)
MX (1) MX2010000385A (https=)
NZ (1) NZ581702A (https=)
PL (1) PL2170942T3 (https=)
PT (1) PT2170942E (https=)
RS (1) RS52976B (https=)
SI (1) SI2170942T1 (https=)
UA (1) UA103598C2 (https=)
WO (1) WO2009000913A1 (https=)
ZA (1) ZA200908168B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ586588A (en) 2008-02-08 2012-10-26 Biogenerix Ag Formulation of ( follice stimulating hormone) fsh and varients with benzalkonium chloride and benzyl alcohol
JP5845170B2 (ja) 2009-04-01 2016-01-20 ラティオファーム ゲーエムベーハー 組換えｆｓｈを精製する方法
EP2325194A1 (en) 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
US9657310B2 (en) * 2012-04-27 2017-05-23 Jcr Pharmaceuticals Co., Ltd. Expression vector
CN103539861B (zh) * 2013-11-01 2015-02-18 广州联康生物科技有限公司 长效重组人促卵泡激素融合蛋白
CN103554269B (zh) * 2013-11-01 2015-02-11 广州联康生物科技有限公司 重组猪促卵泡激素融合蛋白
CN103539860B (zh) * 2013-11-01 2014-12-03 广州优联康医药科技有限公司 一种长效重组人促卵泡激素融合蛋白
CN105462909B (zh) * 2015-12-31 2019-09-27 哈药集团技术中心 一种高效表达人促卵泡激素的cho细胞的培养方法
CN107460206B (zh) * 2017-09-11 2020-05-01 深圳市深研生物科技有限公司 人fsh的重组表达载体、重组细胞株及重组人fsh的制备方法
CN111349154A (zh) * 2018-12-21 2020-06-30 江苏众红生物工程创药研究院有限公司 一种重组人促卵泡激素及其制备方法和药物应用
CN110812366B (zh) * 2019-11-18 2023-11-17 珠海丽凡达生物技术有限公司 一种可用于激素补充的mRNA药物及其制备方法
CN120519466A (zh) * 2025-07-23 2025-08-22 苏州晟济药业有限公司 卵泡刺激素表达系统

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923805A (en) 1983-11-02 1990-05-08 Integrated Genetics, Inc. Fsh
IT1206302B (it) 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
CA2018676C (en) 1989-06-20 2003-05-06 Christie A. Kelton Novel heteropolymeric protein production methods
US6183987B1 (en) 1995-02-17 2001-02-06 Stichting Institut Voor Dierhouderij En Diergezonheld Production of biologically active recombinant bovine follicle stimulation hormone (rec bFSH) in the baculovirus expression system
IL122732A0 (en) 1997-01-15 1998-08-16 Akzo Nobel Nv Liquid gonadotropin-containing formulation its preparation and a device containing same
IL140984A0 (en) 1998-07-23 2002-02-10 Lilly Co Eli Fsh and fsh variant formulations, products and methods
BRPI0010677B8 (pt) 1999-04-16 2021-05-25 Inst Massone S A processo de purificação de gonadotropinas urinárias humanas a partir de gonadotropinas brutas.
US20020127652A1 (en) 2000-02-11 2002-09-12 Schambye Hans Thalsgard Follicle stimulating hormones
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones
JP2006500927A (ja) * 2002-09-13 2006-01-12 ザ・ユニバーシティ・オブ・クイーンズランド コドン翻訳効率に基づく遺伝子発現系
KR100533794B1 (ko) * 2003-10-02 2005-12-07 주식회사 프로젠 인간 난포자극 호르몬을 대량으로 생산하는 방법
EP1697412B1 (en) 2003-12-22 2009-10-21 Ares Trading S.A. Method for purifying fsh
DE602005009856D1 (de) 2004-11-09 2008-10-30 Ares Trading Sa Verfahren zur reinigung von fsh
TWI369401B (en) * 2005-07-05 2012-08-01 Ares Trading Sa Serum-free culture medium for the production of recombinant gonadotropins
US20070281883A1 (en) 2006-06-05 2007-12-06 Hanna Rosenfeld Development of follicle stimulating hormone agonists and antagonists in fish

Also Published As

Publication number Publication date
EP2492280A1 (en) 2012-08-29
CN101720332A (zh) 2010-06-02
IL202280A (en) 2014-12-31
KR101522217B1 (ko) 2015-05-21
DK2170942T3 (da) 2013-11-04
UA103598C2 (uk) 2013-11-11
ZA200908168B (en) 2010-07-28
KR20100051632A (ko) 2010-05-17
PL2170942T3 (pl) 2013-12-31
EP2170942A1 (en) 2010-04-07
BRPI0813913B1 (pt) 2022-04-19
HK1140782A1 (en) 2010-10-22
BRPI0813913A2 (pt) 2014-12-30
SI2170942T1 (sl) 2013-12-31
CA2690844C (en) 2016-05-17
EA201070071A1 (ru) 2010-10-29
CN101720332B (zh) 2014-08-13
RS52976B (sr) 2014-02-28
HRP20130921T1 (hr) 2013-11-08
MX2010000385A (es) 2010-03-29
US8318457B2 (en) 2012-11-27
JP2010531148A (ja) 2010-09-24
CA2690844A1 (en) 2008-12-31
JP5570980B2 (ja) 2014-08-13
AU2008267138A1 (en) 2008-12-31
EA022993B1 (ru) 2016-04-29
IL202280A0 (en) 2010-06-16
NZ581702A (en) 2011-10-28
EP2170942B1 (en) 2013-07-31
CY1114463T1 (el) 2016-10-05
US20120034655A1 (en) 2012-02-09
WO2009000913A1 (en) 2008-12-31
BRPI0813913A8 (pt) 2018-02-14
AU2008267138B9 (en) 2014-06-05
AU2008267138B2 (en) 2014-01-16
ES2432183T3 (es) 2013-12-02

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