PT2170942E - Clone celular produtor de fsh - Google Patents
Clone celular produtor de fshInfo
- Publication number
- PT2170942E PT2170942E PT87744397T PT08774439T PT2170942E PT 2170942 E PT2170942 E PT 2170942E PT 87744397 T PT87744397 T PT 87744397T PT 08774439 T PT08774439 T PT 08774439T PT 2170942 E PT2170942 E PT 2170942E
- Authority
- PT
- Portugal
- Prior art keywords
- nucleic acid
- present
- fsh
- recombinant
- relates
- Prior art date
Links
- 210000004368 gonadotroph Anatomy 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 6
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 102000003864 Human Follicle Stimulating Hormone Human genes 0.000 abstract 3
- 108010082302 Human Follicle Stimulating Hormone Proteins 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 108700010070 Codon Usage Proteins 0.000 abstract 1
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 abstract 1
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 abstract 1
- 229940028334 follicle stimulating hormone Drugs 0.000 abstract 1
- 238000004114 suspension culture Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Reproductive Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07111257 | 2007-06-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2170942E true PT2170942E (pt) | 2013-10-22 |
Family
ID=39745099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87744397T PT2170942E (pt) | 2007-06-28 | 2008-06-27 | Clone celular produtor de fsh |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8318457B2 (https=) |
| EP (2) | EP2492280A1 (https=) |
| JP (1) | JP5570980B2 (https=) |
| KR (1) | KR101522217B1 (https=) |
| CN (1) | CN101720332B (https=) |
| AU (1) | AU2008267138B9 (https=) |
| BR (1) | BRPI0813913B1 (https=) |
| CA (1) | CA2690844C (https=) |
| CY (1) | CY1114463T1 (https=) |
| DK (1) | DK2170942T3 (https=) |
| EA (1) | EA022993B1 (https=) |
| ES (1) | ES2432183T3 (https=) |
| HR (1) | HRP20130921T1 (https=) |
| IL (1) | IL202280A (https=) |
| MX (1) | MX2010000385A (https=) |
| NZ (1) | NZ581702A (https=) |
| PL (1) | PL2170942T3 (https=) |
| PT (1) | PT2170942E (https=) |
| RS (1) | RS52976B (https=) |
| SI (1) | SI2170942T1 (https=) |
| UA (1) | UA103598C2 (https=) |
| WO (1) | WO2009000913A1 (https=) |
| ZA (1) | ZA200908168B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2249869B1 (en) | 2008-02-08 | 2011-09-07 | BioGeneriX AG | Liquid formulation of fsh |
| MX2011010480A (es) | 2009-04-01 | 2012-09-07 | Biogenerix Ag | Metodo para purificar una fsh recombinante. |
| EP2325194A1 (en) | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
| WO2013161958A1 (ja) * | 2012-04-27 | 2013-10-31 | 日本ケミカルリサーチ株式会社 | 新規な発現ベクター |
| CN103554269B (zh) * | 2013-11-01 | 2015-02-11 | 广州联康生物科技有限公司 | 重组猪促卵泡激素融合蛋白 |
| CN103539860B (zh) * | 2013-11-01 | 2014-12-03 | 广州优联康医药科技有限公司 | 一种长效重组人促卵泡激素融合蛋白 |
| CN103539861B (zh) * | 2013-11-01 | 2015-02-18 | 广州联康生物科技有限公司 | 长效重组人促卵泡激素融合蛋白 |
| CN105462909B (zh) * | 2015-12-31 | 2019-09-27 | 哈药集团技术中心 | 一种高效表达人促卵泡激素的cho细胞的培养方法 |
| CN107460206B (zh) * | 2017-09-11 | 2020-05-01 | 深圳市深研生物科技有限公司 | 人fsh的重组表达载体、重组细胞株及重组人fsh的制备方法 |
| CN111349154A (zh) * | 2018-12-21 | 2020-06-30 | 江苏众红生物工程创药研究院有限公司 | 一种重组人促卵泡激素及其制备方法和药物应用 |
| CN110812366B (zh) * | 2019-11-18 | 2023-11-17 | 珠海丽凡达生物技术有限公司 | 一种可用于激素补充的mRNA药物及其制备方法 |
| CN120519466A (zh) * | 2025-07-23 | 2025-08-22 | 苏州晟济药业有限公司 | 卵泡刺激素表达系统 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923805A (en) | 1983-11-02 | 1990-05-08 | Integrated Genetics, Inc. | Fsh |
| IT1206302B (it) | 1987-06-26 | 1989-04-14 | Serono Cesare Ist Ricerca | Ormone follicolo-stimolante urinario |
| CA2018676C (en) | 1989-06-20 | 2003-05-06 | Christie A. Kelton | Novel heteropolymeric protein production methods |
| WO1996025496A1 (en) | 1995-02-17 | 1996-08-22 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | PRODUCTION OF BIOLOGICALLY ACTIVE RECOMBINANT BOVINE FOLLICLE STIMULATING HORMONE (REC bFSH) IN THE BACULOVIRUS EXPRESSION SYSTEM |
| IL122732A0 (en) | 1997-01-15 | 1998-08-16 | Akzo Nobel Nv | Liquid gonadotropin-containing formulation its preparation and a device containing same |
| CN1309567A (zh) | 1998-07-23 | 2001-08-22 | 伊莱利利公司 | Fsh和fsh变体制剂,产品和方法 |
| ES2284494T3 (es) | 1999-04-16 | 2007-11-16 | Instituto Massone S.A. | Procedimiento para preparar composiciones de gonadotropina. |
| US20020127652A1 (en) | 2000-02-11 | 2002-09-12 | Schambye Hans Thalsgard | Follicle stimulating hormones |
| AU2001231531A1 (en) * | 2000-02-11 | 2001-08-20 | Maxygen Aps | Follicle stimulating hormones |
| JP2006500927A (ja) * | 2002-09-13 | 2006-01-12 | ザ・ユニバーシティ・オブ・クイーンズランド | コドン翻訳効率に基づく遺伝子発現系 |
| KR100533794B1 (ko) * | 2003-10-02 | 2005-12-07 | 주식회사 프로젠 | 인간 난포자극 호르몬을 대량으로 생산하는 방법 |
| CA2544333A1 (en) | 2003-12-22 | 2005-07-14 | Ares Trading S.A. | Method for purifying fsh |
| AU2005303818B2 (en) | 2004-11-09 | 2011-06-23 | Ares Trading S.A. | Method for purifying FSH |
| TWI369401B (en) * | 2005-07-05 | 2012-08-01 | Ares Trading Sa | Serum-free culture medium for the production of recombinant gonadotropins |
| US20070281883A1 (en) | 2006-06-05 | 2007-12-06 | Hanna Rosenfeld | Development of follicle stimulating hormone agonists and antagonists in fish |
-
2008
- 2008-06-27 RS RS20130443A patent/RS52976B/sr unknown
- 2008-06-27 AU AU2008267138A patent/AU2008267138B9/en active Active
- 2008-06-27 BR BRPI0813913-0A patent/BRPI0813913B1/pt not_active IP Right Cessation
- 2008-06-27 CN CN200880022358.7A patent/CN101720332B/zh not_active Expired - Fee Related
- 2008-06-27 EA EA201070071A patent/EA022993B1/ru not_active IP Right Cessation
- 2008-06-27 PL PL08774439T patent/PL2170942T3/pl unknown
- 2008-06-27 PT PT87744397T patent/PT2170942E/pt unknown
- 2008-06-27 EP EP12169533A patent/EP2492280A1/en not_active Withdrawn
- 2008-06-27 CA CA2690844A patent/CA2690844C/en not_active Expired - Fee Related
- 2008-06-27 MX MX2010000385A patent/MX2010000385A/es active IP Right Grant
- 2008-06-27 US US12/666,257 patent/US8318457B2/en not_active Expired - Fee Related
- 2008-06-27 JP JP2010513938A patent/JP5570980B2/ja not_active Expired - Fee Related
- 2008-06-27 UA UAA201000813A patent/UA103598C2/uk unknown
- 2008-06-27 ES ES08774439T patent/ES2432183T3/es active Active
- 2008-06-27 SI SI200831065T patent/SI2170942T1/sl unknown
- 2008-06-27 HR HRP20130921AT patent/HRP20130921T1/hr unknown
- 2008-06-27 EP EP08774439.7A patent/EP2170942B1/en active Active
- 2008-06-27 WO PCT/EP2008/058274 patent/WO2009000913A1/en not_active Ceased
- 2008-06-27 KR KR1020107001959A patent/KR101522217B1/ko not_active Expired - Fee Related
- 2008-06-27 DK DK08774439.7T patent/DK2170942T3/da active
- 2008-06-27 NZ NZ581702A patent/NZ581702A/en not_active IP Right Cessation
-
2009
- 2009-11-20 ZA ZA200908168A patent/ZA200908168B/xx unknown
- 2009-11-23 IL IL202280A patent/IL202280A/en active IP Right Grant
-
2013
- 2013-10-09 CY CY20131100874T patent/CY1114463T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT2170942E (pt) | Clone celular produtor de fsh | |
| PH12020551039A1 (en) | Non-viral dna vectors and uses thereof for antibody and fusion protein production | |
| MX2009002388A (es) | Uso de celulas humanas originarias de leucemia mieloide para la expresion de anticuerpos. | |
| SG10201808730VA (en) | Cross-species-specific binding domain | |
| MX345729B (es) | Proteina activadora del ensamblaje (aap) y su uso para la fabricacion de particulas de parvovirus que consisten esencialmente de vp3. | |
| EA201170506A1 (ru) | Генная терапия порфобилиногендезаминазой | |
| WO2008114673A1 (ja) | ポリペプチドの製造方法 | |
| MY156855A (en) | Novel regulatory elements | |
| MX2009002816A (es) | Proteinas de fusion de albumina. | |
| NZ608972A (en) | Engineered nucleic acids and methods of use thereof | |
| EP3805348A3 (en) | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same | |
| ATE492633T1 (de) | Polypeptide mit cellobiohydrolaseaktivität und dafür kodierende polynukleotide | |
| MX2012006096A (es) | Polipeptidos que tienen actividad glucoamilasa y polinucleotidos que codifican para los mismos. | |
| MX2014001070A (es) | Gen plaguicida axmi279 y sus metodos de uso. | |
| EA201300058A1 (ru) | Полипептид, обладающий бета-глюкозидазной активностью, и его применение | |
| MX2012003473A (es) | Polipeptidos que tienen actividad celulitica mejorada y polinucleotidos que codifican para los mismos. | |
| NZ596735A (en) | Recombinant production of peptides | |
| MX2012006095A (es) | Polipeptidos que tienen actividad glucoamilasa y polinucleotidos que codifican para los mismos. | |
| AR116615A2 (es) | Operaciones de cosecha mejoradas para proteínas recombinadas | |
| WO2009069381A1 (ja) | フラビンアデニンジヌクレオチド結合型グルコース脱水素酵素遺伝子が導入された形質転換体、及び該形質転換体を用いたフラビンアデニンジヌクレオチド結合型グルコース脱水素酵素の製造法 | |
| MX2010004573A (es) | Polinucleotidos y metodos para mejoramiento de plantas. | |
| ATE546464T1 (de) | Verfahren zur produktion von rekombinantem protein in cho-zellen | |
| MY156447A (en) | Methods and polynucleotides for improving plants | |
| MY186538A (en) | Nucleotide sequence encoding wushel-related homebox4 (wox4) protein from corchorus olitorius and corchorus capsularis and method of use for same | |
| MX2019013413A (es) | Guayule con mayor produccion y rendimiento de caucho. |