CY1111816T1 - Παραγωγο θειαδιαζολινης για την θεραπεια του καρκινου - Google Patents
Παραγωγο θειαδιαζολινης για την θεραπεια του καρκινουInfo
- Publication number
- CY1111816T1 CY1111816T1 CY20111100863T CY111100863T CY1111816T1 CY 1111816 T1 CY1111816 T1 CY 1111816T1 CY 20111100863 T CY20111100863 T CY 20111100863T CY 111100863 T CY111100863 T CY 111100863T CY 1111816 T1 CY1111816 T1 CY 1111816T1
- Authority
- CY
- Cyprus
- Prior art keywords
- substituted
- thiadiazolin
- product
- unsubstituted
- cancer treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
(όπου τα R1 και R4 είναι ίδια ή διαφορετικά και καθένα αντιπροσωπεύει ένα άτομο υδρογόνου, υποκατεστημένο ή μη υποκατεστημένο κατώτερο αλκυλο, υποκατεστημένο ή μη υποκατεστημένο κατώτερο αλκινυλο, υποκατεστημένο ή μη υποκατεστημένο κατώτερο αλκενυλο, κλπ· το R5 αντιπροσωπεύει υποκατεστημένη ή μη υποκατεστημένη ετεροκυκλική ομάδα, υποκατεστημένο ή μη υποκατεστημένο αρυλο, κλπ· το R2 αντιπροσωπεύει -C(=W)R6 κλπ· το R3 αντιπροσωπεύει ένα άτομο υδρογόνου, -C(=WA)R6A κλπ). Μέσα κατά των όγκων που περιέχουν ένα παράγωγο θειαδιαζολίνης που αντιπροσωπεύεται από τον προαναφερθέντα γενικό τύπο (I) ή ένα φαρμακολογικώς αποδεκτό άλας αυτού ως δραστικό συστατικό παρέχονται.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001377456 | 2001-12-11 | ||
| JP2002237399 | 2002-08-16 | ||
| EP07015426A EP1847534B9 (en) | 2001-12-11 | 2002-12-11 | Thiadiazoline derivatives for treating cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111816T1 true CY1111816T1 (el) | 2015-10-07 |
Family
ID=26624996
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20101100996T CY1112899T1 (el) | 2001-12-11 | 2010-11-04 | Παραγωγα θειαδιαζολινης για τη θεραπεια του καρκινου |
| CY20111100863T CY1111816T1 (el) | 2001-12-11 | 2011-09-07 | Παραγωγο θειαδιαζολινης για την θεραπεια του καρκινου |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20101100996T CY1112899T1 (el) | 2001-12-11 | 2010-11-04 | Παραγωγα θειαδιαζολινης για τη θεραπεια του καρκινου |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US7425636B2 (el) |
| EP (2) | EP1454903B9 (el) |
| JP (1) | JP4272994B2 (el) |
| KR (1) | KR100915287B1 (el) |
| CN (1) | CN100484928C (el) |
| AT (2) | ATE480527T1 (el) |
| AU (1) | AU2002354465B2 (el) |
| CA (1) | CA2469801C (el) |
| CY (2) | CY1112899T1 (el) |
| DE (1) | DE60237637D1 (el) |
| DK (2) | DK1454903T3 (el) |
| ES (1) | ES2350642T3 (el) |
| HK (1) | HK1107814A1 (el) |
| PT (2) | PT1454903E (el) |
| SI (2) | SI1454903T1 (el) |
| WO (1) | WO2003051854A1 (el) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003051854A1 (en) | 2001-12-11 | 2003-06-26 | Kyowa Hakko Kogyo Co., Ltd. | Thiadiazoline derivative |
| ATE537158T1 (de) * | 2003-04-18 | 2011-12-15 | Kyowa Hakko Kirin Co Ltd | M-stage-kinesin-inhibitor |
| JPWO2004111023A1 (ja) * | 2003-06-10 | 2006-07-27 | 協和醗酵工業株式会社 | チアジアゾリン−１−オキシド誘導体 |
| AU2004247551A1 (en) * | 2003-06-10 | 2004-12-23 | Fuji Photo Film Co., Ltd. | Thiadiazoline derivative |
| JPWO2005035512A1 (ja) * | 2003-10-10 | 2006-12-21 | 協和醗酵工業株式会社 | チアジアゾリン誘導体 |
| WO2005061707A1 (ja) * | 2003-12-24 | 2005-07-07 | Kyowa Hakko Kogyo Co., Ltd. | 癌細胞のEg5阻害剤に対する感受性を判定する方法 |
| US7449486B2 (en) * | 2004-10-19 | 2008-11-11 | Array Biopharma Inc. | Mitotic kinesin inhibitors and methods of use thereof |
| AU2006225636A1 (en) * | 2005-03-22 | 2006-09-28 | Fujifilm Corporation | Therapeutic agent for solid tumor |
| KR20070114822A (ko) * | 2005-03-22 | 2007-12-04 | 교와 핫꼬 고교 가부시끼가이샤 | 조혈기 종양 치료제 |
| UA95907C2 (en) * | 2005-05-02 | 2011-09-26 | Эррей Биофарма Инк. | Mitotic kinesin inhibitors and methods of use thereof |
| US7910611B2 (en) | 2005-06-24 | 2011-03-22 | Kyowa Hakko Kirin Co., Ltd. | Therapeutic agent for restenosis |
| DE102005055354A1 (de) * | 2005-11-21 | 2007-10-31 | Merck Patent Gmbh | Substituierte 5-Phenyl-3,6-dihydro-2-oxo-6H-[1,3,4]thiadiazine |
| DE102006002065B4 (de) * | 2006-01-16 | 2007-11-29 | Infineon Technologies Austria Ag | Kompensationsbauelement mit reduziertem und einstellbarem Einschaltwiderstand |
| EP2081918A2 (en) * | 2006-10-03 | 2009-07-29 | Array Biopharma, Inc. | Mitotic kinesin inhibitors and methods of use thereof |
| EP2178508B1 (en) | 2007-07-12 | 2013-02-06 | Eli Lilly And Company | Stable formulations of thiadiazole derivative |
| US8796460B2 (en) | 2007-10-19 | 2014-08-05 | Mercky Sharp & Dohme Corp. | Compounds for inhibiting KSP kinesin activity |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE244989C (el) | ||||
| US4246225A (en) * | 1978-05-25 | 1981-01-20 | Owens-Illinois, Inc. | Method for forming tubular plastic articles |
| US4346225A (en) * | 1981-06-15 | 1982-08-24 | Eli Lilly And Company | Herbicidal 2-methylamino thiadiazolines |
| US4338449A (en) * | 1981-06-15 | 1982-07-06 | Eli Lilly And Company | Herbicidal thiadiazolines |
| US4699913A (en) | 1985-06-28 | 1987-10-13 | Ciba-Geigy Corporation | Substituted 4,5-dihydro-1,3,4-thiadiazoles useful as insecticides |
| ATE72431T1 (de) | 1985-08-31 | 1992-02-15 | Fisons Plc | 5-gliedrige heterocyclische angiotensinumwandlungsenzym-inhibitoren. |
| DD243930A1 (de) | 1985-12-04 | 1987-03-18 | Akad Wissenschaften Ddr | Verfahren zur herstellung von neuen 5,5-disubstituierten 4-carbamoyl-4,5-dihydro-1,3,4-thiadiazol-2-yl-harnstoffen |
| AU4288293A (en) | 1992-04-27 | 1993-11-29 | E.I. Du Pont De Nemours And Company | Fungicidal 1,3,4-oxadiazines and 1,3,4-thiadiazines |
| JP2798005B2 (ja) | 1994-05-19 | 1998-09-17 | 三菱化学株式会社 | 平滑筋細胞増殖に起因する疾患の治療・予防剤 |
| EP0682947B1 (en) * | 1994-05-19 | 1997-09-10 | Mitsubishi Chemical Corporation | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia |
| US5814647A (en) * | 1997-03-04 | 1998-09-29 | Board Of Regents, The University Of Texas System | Use of troglitazone and related compounds for the treatment of the climacteric symptoms |
| US6235762B1 (en) * | 1998-11-23 | 2001-05-22 | American Cyanamid Company | 2-aryl-Δ2-1,3,4-(oxa and thia)diazoline insecticidal and acaricidal agents |
| JP2000159756A (ja) | 1998-11-23 | 2000-06-13 | American Cyanamid Co | ２―アリ―ル―δ２―１，３，４―（オキサおよびチア）ジアゾリン殺虫および殺ダニ剤 |
| NZ513432A (en) * | 1999-01-13 | 2004-02-27 | Warner Lambert Co | 1-heterocycle substituted diarylamines |
| JP2000204077A (ja) * | 1999-01-13 | 2000-07-25 | Warner Lambert Co | ジアリ―ルアミン |
| JP2000229959A (ja) * | 1999-02-04 | 2000-08-22 | Sumitomo Pharmaceut Co Ltd | Ｓｔａｔ６活性化阻害剤 |
| US7230000B1 (en) * | 1999-10-27 | 2007-06-12 | Cytokinetics, Incorporated | Methods and compositions utilizing quinazolinones |
| US6617115B1 (en) * | 1999-10-27 | 2003-09-09 | Cytokinetics, Inc. | Methods of screening for modulators of cell proliferation |
| US6545004B1 (en) * | 1999-10-27 | 2003-04-08 | Cytokinetics, Inc. | Methods and compositions utilizing quinazolinones |
| DE60028227T2 (de) | 1999-10-27 | 2007-03-29 | Cytokinetics, Inc., South San Francisco | Chinazolinone benutzende verfahren und zusammenstellungen |
| WO2001056994A1 (en) * | 2000-02-04 | 2001-08-09 | Biogen, Inc. | Integrin antagonists |
| US6310716B1 (en) | 2000-08-18 | 2001-10-30 | Corning Incorporated | Amplifier system with a discrete Raman fiber amplifier module |
| WO2002056880A1 (en) | 2001-01-19 | 2002-07-25 | Cytokinetics, Inc. | Triphenylmethane kinesin inhibitors |
| US6992082B2 (en) * | 2001-01-19 | 2006-01-31 | Cytokinetics, Inc. | Phenothiazine kinesin inhibitors |
| US20040087548A1 (en) | 2001-02-27 | 2004-05-06 | Salvati Mark E. | Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
| US6809102B2 (en) * | 2001-03-29 | 2004-10-26 | Bristol-Myers Squibb Company | Cyano-substituted dihydropyrimidine compounds and their use to treat diseases |
| IL158083A0 (en) * | 2001-03-29 | 2004-03-28 | Bristol Myers Squibb Co | A PHARMACEUTICAL COMPOSITION CONTAINING AN Eg5 PROTEIN INHIBITOR |
| US6900214B2 (en) * | 2001-03-29 | 2005-05-31 | Bristol-Myers Squibb Company | Cyano-substituted dihydropyrimidine compounds and their use to treat diseases |
| US7060705B2 (en) * | 2001-11-07 | 2006-06-13 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
| WO2003051854A1 (en) * | 2001-12-11 | 2003-06-26 | Kyowa Hakko Kogyo Co., Ltd. | Thiadiazoline derivative |
| US6561831B1 (en) | 2001-12-27 | 2003-05-13 | Hon Hai Precision Ind. Co., Ltd. | Housing of socket connector and conductive terminal thereof |
| JP4399269B2 (ja) * | 2002-03-08 | 2010-01-13 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂性キネシン阻害薬 |
| US20050203110A1 (en) * | 2002-05-23 | 2005-09-15 | Coleman Paul J. | Mitotic kinesin inhibitors |
| ATE537158T1 (de) * | 2003-04-18 | 2011-12-15 | Kyowa Hakko Kirin Co Ltd | M-stage-kinesin-inhibitor |
| JPWO2004111023A1 (ja) | 2003-06-10 | 2006-07-27 | 協和醗酵工業株式会社 | チアジアゾリン−１−オキシド誘導体 |
| AU2004247551A1 (en) * | 2003-06-10 | 2004-12-23 | Fuji Photo Film Co., Ltd. | Thiadiazoline derivative |
| JPWO2005035512A1 (ja) * | 2003-10-10 | 2006-12-21 | 協和醗酵工業株式会社 | チアジアゾリン誘導体 |
| US7449486B2 (en) | 2004-10-19 | 2008-11-11 | Array Biopharma Inc. | Mitotic kinesin inhibitors and methods of use thereof |
| KR20070114822A (ko) | 2005-03-22 | 2007-12-04 | 교와 핫꼬 고교 가부시끼가이샤 | 조혈기 종양 치료제 |
| AU2006225636A1 (en) | 2005-03-22 | 2006-09-28 | Fujifilm Corporation | Therapeutic agent for solid tumor |
| US7910611B2 (en) | 2005-06-24 | 2011-03-22 | Kyowa Hakko Kirin Co., Ltd. | Therapeutic agent for restenosis |
-
2002
- 2002-12-11 WO PCT/JP2002/012961 patent/WO2003051854A1/ja active Application Filing
- 2002-12-11 EP EP02788786A patent/EP1454903B9/en not_active Expired - Lifetime
- 2002-12-11 JP JP2003552739A patent/JP4272994B2/ja not_active Expired - Fee Related
- 2002-12-11 SI SI200230923T patent/SI1454903T1/sl unknown
- 2002-12-11 DK DK02788786.8T patent/DK1454903T3/da active
- 2002-12-11 EP EP07015426A patent/EP1847534B9/en not_active Expired - Lifetime
- 2002-12-11 CN CNB028279840A patent/CN100484928C/zh not_active Expired - Fee Related
- 2002-12-11 SI SI200230956T patent/SI1847534T1/sl unknown
- 2002-12-11 AU AU2002354465A patent/AU2002354465B2/en not_active Ceased
- 2002-12-11 DE DE60237637T patent/DE60237637D1/de not_active Expired - Lifetime
- 2002-12-11 KR KR1020047008915A patent/KR100915287B1/ko not_active IP Right Cessation
- 2002-12-11 ES ES02788786T patent/ES2350642T3/es not_active Expired - Lifetime
- 2002-12-11 CA CA2469801A patent/CA2469801C/en not_active Expired - Fee Related
- 2002-12-11 PT PT02788786T patent/PT1454903E/pt unknown
- 2002-12-11 DK DK07015426.5T patent/DK1847534T3/da active
- 2002-12-11 US US10/497,531 patent/US7425636B2/en not_active Expired - Fee Related
- 2002-12-11 PT PT07015426T patent/PT1847534E/pt unknown
- 2002-12-11 AT AT02788786T patent/ATE480527T1/de active
- 2002-12-11 AT AT07015426T patent/ATE513821T1/de active
-
2007
- 2007-05-11 US US11/798,214 patent/US20070213380A1/en not_active Abandoned
-
2008
- 2008-02-06 HK HK08101484.3A patent/HK1107814A1/xx not_active IP Right Cessation
- 2008-04-07 US US12/098,736 patent/US7759371B2/en not_active Expired - Fee Related
-
2010
- 2010-06-02 US US12/792,448 patent/US7902234B2/en not_active Expired - Fee Related
- 2010-11-04 CY CY20101100996T patent/CY1112899T1/el unknown
-
2011
- 2011-09-07 CY CY20111100863T patent/CY1111816T1/el unknown
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