CY1110954T1 - Ημιστερεες βλεννοκολλωδεις φαρμακοτεχνικες μορφες - Google Patents
Ημιστερεες βλεννοκολλωδεις φαρμακοτεχνικες μορφεςInfo
- Publication number
- CY1110954T1 CY1110954T1 CY20101101079T CY101101079T CY1110954T1 CY 1110954 T1 CY1110954 T1 CY 1110954T1 CY 20101101079 T CY20101101079 T CY 20101101079T CY 101101079 T CY101101079 T CY 101101079T CY 1110954 T1 CY1110954 T1 CY 1110954T1
- Authority
- CY
- Cyprus
- Prior art keywords
- semi
- solid
- pharmaceutical forms
- mucosal adhesives
- mucosal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Adhesive Tapes (AREA)
Abstract
Η εφεύρεση σχετίζεται με ημιστερεές βλεννοκολλώδεις φαρμακοτεχνικές μορφές για κολπική χρήση, που έχουν βελτιωμένα τεχνικά και οργανοληπτικά χαρακτηριστικά. Οι φαρμακοτεχνικές μορφές της εφεύρεσης περιέχουν τουλάχιστον δύο βιοκολλώδη πολυμερή που σχηματίζουν πηκτή και ένα ενεργό συστατικό. Οι αναφερθείσες φαρμακοτεχνικές μορφές μπορούν να χρησιμοποιηθούν για να αποτρέψουν και/ή να θεραπεύσουν διάφορες παθολογικές καταστάσεις και διαταραχές σε ανθρώπους και ζώα.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200301672A ES2237298B1 (es) | 2003-07-16 | 2003-07-16 | Formulaciones mucoadhesivas semisolidas. |
EP04742064A EP1652535B1 (en) | 2003-07-16 | 2004-07-16 | Semi-solid mucoadhesive formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110954T1 true CY1110954T1 (el) | 2015-06-11 |
Family
ID=34072910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101101079T CY1110954T1 (el) | 2003-07-16 | 2010-11-25 | Ημιστερεες βλεννοκολλωδεις φαρμακοτεχνικες μορφες |
Country Status (13)
Country | Link |
---|---|
US (1) | US8663688B2 (el) |
EP (2) | EP2100612A3 (el) |
JP (1) | JP4891765B2 (el) |
AT (1) | ATE482723T1 (el) |
CY (1) | CY1110954T1 (el) |
DE (1) | DE602004029369D1 (el) |
DK (1) | DK1652535T3 (el) |
ES (2) | ES2237298B1 (el) |
HR (1) | HRP20100635T1 (el) |
PL (1) | PL1652535T3 (el) |
PT (1) | PT1652535E (el) |
SI (1) | SI1652535T1 (el) |
WO (1) | WO2005007194A1 (el) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
EP1667619A4 (en) | 2003-09-19 | 2007-10-10 | Drugtech Corp | PHARMACEUTICAL FEEDING SYSTEM |
EP1896078A1 (en) * | 2005-06-16 | 2008-03-12 | Warner Chilcott Company, Inc. | Estrogen compositions for vaginal administration |
EP1898880A2 (en) * | 2005-06-16 | 2008-03-19 | Warner Chilcott Company Inc. | Gel compositions for topical administration |
US10016442B2 (en) * | 2005-06-16 | 2018-07-10 | Allergan Pharmaceuticals International Limited | Estrogen compositions for vaginal administration |
CA2617106A1 (en) * | 2005-08-12 | 2007-02-22 | Drugtech Corporation | Estrogen compositions and therapeutic methods of use thereof |
CN101405006A (zh) * | 2006-01-20 | 2009-04-08 | 梨树医药公司 | 治疗萎缩性阴道炎的方法 |
DK2018164T3 (en) | 2006-05-12 | 2017-06-12 | Christian Noe | Use of combination preparations comprising antimycotics |
EP2034984A4 (en) * | 2006-06-02 | 2013-03-06 | Pear Tree Women S Health Care | PROCESS FOR TREATING ATROPHIC VAGINITIS |
WO2008005783A2 (en) * | 2006-06-30 | 2008-01-10 | Drugtech Corporation | Treatment of non- infectious inflammatory vulvovaginitis with a bioadhesive clindamycin composition |
ES2310968B1 (es) * | 2007-06-25 | 2010-02-08 | Italfarmaco, S.A. | Uso de estriol en bajas dosis. |
ES2344673B1 (es) * | 2008-08-07 | 2011-05-03 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral. |
CA2732626A1 (en) * | 2008-08-12 | 2010-02-18 | Novabay Pharmaceuticals, Inc. | Antimicrobial gel formulations |
BRPI0803568B8 (pt) * | 2008-08-14 | 2021-05-25 | Biolab San Us Farm Ltda | composição mucoaderente |
ES2344675B1 (es) * | 2008-12-19 | 2011-04-28 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
EA023396B1 (ru) * | 2010-04-01 | 2016-05-31 | Фарманест Аб | Термогелеобразующие композиции анестетиков |
CN102293735B (zh) * | 2011-08-19 | 2013-05-01 | 辽宁万嘉医药科技有限公司 | 一种抗真菌咪唑类药物缓释凝胶和制备方法 |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
ES2885523T3 (es) | 2011-11-23 | 2021-12-14 | Therapeuticsmd Inc | Formulaciones y terapias de reposición hormonal de combinación naturales |
CN102600288B (zh) * | 2012-04-20 | 2014-03-05 | 广西源安堂药业有限公司 | 一种治疗阴道炎的复方黄松凝胶药物及其制备方法 |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10045935B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
KR101358993B1 (ko) | 2012-09-05 | 2014-02-06 | 임혜선 | 네일 프린팅용 트랜스퍼 솔루션 및 이를 이용한 네일 프린팅 방법 |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
JP2017523138A (ja) | 2014-07-29 | 2017-08-17 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 経皮クリーム |
US20160175271A1 (en) * | 2014-12-19 | 2016-06-23 | Gavis Pharmaceuticals | Rectal suppository for ulcerative colitis |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
ES2949053T3 (es) * | 2016-01-07 | 2023-09-25 | Viramal Ltd | Composiciones de gel para administración transdérmica para maximizar las concentraciones de fármaco en el estrato córneo y suero, y métodos de uso de las mismas |
US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
CN113164384A (zh) | 2018-10-26 | 2021-07-23 | 维拉莫有限公司 | 黏膜粘附性凝胶组合物 |
CN110151680A (zh) * | 2019-04-10 | 2019-08-23 | 重庆医药高等专科学校 | 雌三醇凝胶产品及制备方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4615697A (en) | 1983-11-14 | 1986-10-07 | Bio-Mimetics, Inc. | Bioadhesive compositions and methods of treatment therewith |
NZ222698A (en) | 1987-01-08 | 1990-02-26 | Squibb & Sons Inc | Bioadhesive suppository formulations comprising a medicament, water, a hydrocolloid and low melting point base |
US5719197A (en) * | 1988-03-04 | 1998-02-17 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
DK0431719T3 (da) | 1989-10-31 | 1995-02-27 | Columbia Lab Inc | Vaginalt vævsbefugtende præparat |
DK0500807T3 (da) | 1989-10-31 | 2000-02-07 | Columbia Lab Inc | Præparat og fremgangsmåde til befugtning af væv |
US5543150A (en) | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
US5667492A (en) * | 1994-10-07 | 1997-09-16 | Columbia Laboratories, Inc. | Use and composition of an anti-sexually transmitted diseases formulation |
AT408067B (de) * | 1995-03-17 | 2001-08-27 | Gebro Pharma Gmbh | Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung |
US5741525A (en) | 1995-10-24 | 1998-04-21 | Marshall University Research Corporation | Vaginal pharmaceutical hydrogen peroxide composition |
AU714797B2 (en) | 1996-06-14 | 2000-01-13 | Mcneil-Ppc, Inc. | Moisture containing compositions that are spreadable onto and adherable to biomembranes, methods of making and use thereof |
IT1284874B1 (it) | 1996-08-02 | 1998-05-22 | Farmigea Spa | Complessi bioadesivi di polycarbophil e farmaci antifungini o antiprotozoari azolici |
US5942243A (en) | 1996-11-12 | 1999-08-24 | Polytherapeutics, Inc. | Mucoadhesive compositions for administration of biologically active agents to animal tissue |
AU729546B2 (en) | 1996-11-14 | 2001-02-01 | Lipomedica Ehf. | Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglyceride derivatives thereof for treating of mucosa infections |
DE69819748T2 (de) | 1997-09-12 | 2004-09-30 | Columbia Laboratories (Bermuda) Ltd. | Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen |
US6159491A (en) | 1999-02-12 | 2000-12-12 | Biovector Technologies, Inc. | Prolonged release bioadhesive vaginal gel dosage form |
EP2275133A1 (en) | 1999-02-26 | 2011-01-19 | Novartis Vaccines and Diagnostics, Inc. | Use of bioadhesives and adjuvants for the mucosal delivery of antigens |
SE522260C2 (sv) | 1999-10-01 | 2004-01-27 | Ericsson Telefon Ab L M | Metod, system och säkerhetsadapter för att exekvera säker dataöverföring i ett trådlöst nät |
UA74168C2 (uk) | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу |
CA2386422A1 (en) * | 1999-10-22 | 2001-04-26 | Lif-Hlaup Ehf. Bio-Gels Pharmaceuticals Inc. | Pharmaceutical composition for treatment of mucosal epithelial ulceration and/or erosion |
ATE355854T1 (de) * | 2000-08-03 | 2007-03-15 | Antares Pharma Ipl Ag | Neue zusammensetzung zur transdermalen und/oder transmukosalen wirkstoffanwendung mit geeignetem therapeutischen spiegel |
US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
US7709026B2 (en) * | 2001-10-29 | 2010-05-04 | Columbia Laboratories, Inc. | Low concentration of peroxide for treating or preventing vaginal infections |
US6967194B1 (en) * | 2002-09-18 | 2005-11-22 | Susan Matsuo | Bio-identical hormones and method of use |
ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
-
2003
- 2003-07-16 ES ES200301672A patent/ES2237298B1/es not_active Expired - Fee Related
-
2004
- 2004-07-16 SI SI200431522T patent/SI1652535T1/sl unknown
- 2004-07-16 EP EP09161078A patent/EP2100612A3/en not_active Withdrawn
- 2004-07-16 AT AT04742064T patent/ATE482723T1/de active
- 2004-07-16 DK DK04742064.1T patent/DK1652535T3/da active
- 2004-07-16 EP EP04742064A patent/EP1652535B1/en active Active
- 2004-07-16 WO PCT/ES2004/000336 patent/WO2005007194A1/es active Application Filing
- 2004-07-16 US US10/565,062 patent/US8663688B2/en active Active
- 2004-07-16 PT PT04742064T patent/PT1652535E/pt unknown
- 2004-07-16 PL PL04742064T patent/PL1652535T3/pl unknown
- 2004-07-16 DE DE602004029369T patent/DE602004029369D1/de active Active
- 2004-07-16 ES ES04742064T patent/ES2353694T3/es active Active
- 2004-07-16 JP JP2006519939A patent/JP4891765B2/ja active Active
-
2010
- 2010-11-24 HR HR20100635T patent/HRP20100635T1/hr unknown
- 2010-11-25 CY CY20101101079T patent/CY1110954T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1652535A1 (en) | 2006-05-03 |
DE602004029369D1 (de) | 2010-11-11 |
EP1652535B1 (en) | 2010-09-29 |
US20060240111A1 (en) | 2006-10-26 |
HRP20100635T1 (hr) | 2010-12-31 |
ES2353694T3 (es) | 2011-03-04 |
JP4891765B2 (ja) | 2012-03-07 |
EP2100612A2 (en) | 2009-09-16 |
SI1652535T1 (sl) | 2010-12-31 |
ATE482723T1 (de) | 2010-10-15 |
ES2237298A1 (es) | 2005-07-16 |
ES2237298B1 (es) | 2006-11-01 |
PL1652535T3 (pl) | 2011-03-31 |
DK1652535T3 (da) | 2010-11-15 |
WO2005007194A1 (es) | 2005-01-27 |
JP2007528864A (ja) | 2007-10-18 |
PT1652535E (pt) | 2010-11-18 |
US8663688B2 (en) | 2014-03-04 |
EP2100612A3 (en) | 2010-06-02 |
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