ATE482723T1 - Halbfeste mukoadhäsive formulierungen - Google Patents

Halbfeste mukoadhäsive formulierungen

Info

Publication number
ATE482723T1
ATE482723T1 AT04742064T AT04742064T ATE482723T1 AT E482723 T1 ATE482723 T1 AT E482723T1 AT 04742064 T AT04742064 T AT 04742064T AT 04742064 T AT04742064 T AT 04742064T AT E482723 T1 ATE482723 T1 AT E482723T1
Authority
AT
Austria
Prior art keywords
semi
mucoadhesive formulations
solid
solid mucoadhesive
formulations
Prior art date
Application number
AT04742064T
Other languages
English (en)
Inventor
Fern Ndez Lvaro Acebran
Garcoea Ana Campuzano
Ndez Martin Rosa Maria Hern
Olaechea Manuela Igartua
Munoz Jose Luis Pedraz
Gascan Alicia Rodroeguez
Original Assignee
Italfarmaco Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Sa filed Critical Italfarmaco Sa
Application granted granted Critical
Publication of ATE482723T1 publication Critical patent/ATE482723T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Adhesive Tapes (AREA)
AT04742064T 2003-07-16 2004-07-16 Halbfeste mukoadhäsive formulierungen ATE482723T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200301672A ES2237298B1 (es) 2003-07-16 2003-07-16 Formulaciones mucoadhesivas semisolidas.
PCT/ES2004/000336 WO2005007194A1 (es) 2003-07-16 2004-07-16 Formulaciones mucoadhesivas semisólidas

Publications (1)

Publication Number Publication Date
ATE482723T1 true ATE482723T1 (de) 2010-10-15

Family

ID=34072910

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04742064T ATE482723T1 (de) 2003-07-16 2004-07-16 Halbfeste mukoadhäsive formulierungen

Country Status (13)

Country Link
US (1) US8663688B2 (de)
EP (2) EP2100612A3 (de)
JP (1) JP4891765B2 (de)
AT (1) ATE482723T1 (de)
CY (1) CY1110954T1 (de)
DE (1) DE602004029369D1 (de)
DK (1) DK1652535T3 (de)
ES (2) ES2237298B1 (de)
HR (1) HRP20100635T1 (de)
PL (1) PL1652535T3 (de)
PT (1) PT1652535E (de)
SI (1) SI1652535T1 (de)
WO (1) WO2005007194A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2237298B1 (es) 2003-07-16 2006-11-01 Italfarmaco, S.A. Formulaciones mucoadhesivas semisolidas.
EP1667619A4 (de) 2003-09-19 2007-10-10 Drugtech Corp Pharmazeutisches zufuhrsystem
EP1896078A1 (de) * 2005-06-16 2008-03-12 Warner Chilcott Company, Inc. Östrogenzusammensetzungen zur vaginalen verabreichung
EP1898880A2 (de) * 2005-06-16 2008-03-19 Warner Chilcott Company Inc. Gelzusammensetzungen zur topischen verabreichung
US10016442B2 (en) * 2005-06-16 2018-07-10 Allergan Pharmaceuticals International Limited Estrogen compositions for vaginal administration
CA2617106A1 (en) * 2005-08-12 2007-02-22 Drugtech Corporation Estrogen compositions and therapeutic methods of use thereof
CN101405006A (zh) * 2006-01-20 2009-04-08 梨树医药公司 治疗萎缩性阴道炎的方法
DK2018164T3 (en) 2006-05-12 2017-06-12 Christian Noe Use of combination preparations comprising antimycotics
EP2034984A4 (de) * 2006-06-02 2013-03-06 Pear Tree Women S Health Care Verfahren zur behandlung atrophischer vaginitis
WO2008005783A2 (en) * 2006-06-30 2008-01-10 Drugtech Corporation Treatment of non- infectious inflammatory vulvovaginitis with a bioadhesive clindamycin composition
ES2310968B1 (es) * 2007-06-25 2010-02-08 Italfarmaco, S.A. Uso de estriol en bajas dosis.
ES2344673B1 (es) * 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
CA2732626A1 (en) * 2008-08-12 2010-02-18 Novabay Pharmaceuticals, Inc. Antimicrobial gel formulations
BRPI0803568B8 (pt) * 2008-08-14 2021-05-25 Biolab San Us Farm Ltda composição mucoaderente
ES2344675B1 (es) * 2008-12-19 2011-04-28 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular.
EA023396B1 (ru) * 2010-04-01 2016-05-31 Фарманест Аб Термогелеобразующие композиции анестетиков
CN102293735B (zh) * 2011-08-19 2013-05-01 辽宁万嘉医药科技有限公司 一种抗真菌咪唑类药物缓释凝胶和制备方法
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
ES2885523T3 (es) 2011-11-23 2021-12-14 Therapeuticsmd Inc Formulaciones y terapias de reposición hormonal de combinación naturales
CN102600288B (zh) * 2012-04-20 2014-03-05 广西源安堂药业有限公司 一种治疗阴道炎的复方黄松凝胶药物及其制备方法
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10045935B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
KR101358993B1 (ko) 2012-09-05 2014-02-06 임혜선 네일 프린팅용 트랜스퍼 솔루션 및 이를 이용한 네일 프린팅 방법
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
JP2017523138A (ja) 2014-07-29 2017-08-17 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 経皮クリーム
US20160175271A1 (en) * 2014-12-19 2016-06-23 Gavis Pharmaceuticals Rectal suppository for ulcerative colitis
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
ES2949053T3 (es) * 2016-01-07 2023-09-25 Viramal Ltd Composiciones de gel para administración transdérmica para maximizar las concentraciones de fármaco en el estrato córneo y suero, y métodos de uso de las mismas
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
CN113164384A (zh) 2018-10-26 2021-07-23 维拉莫有限公司 黏膜粘附性凝胶组合物
CN110151680A (zh) * 2019-04-10 2019-08-23 重庆医药高等专科学校 雌三醇凝胶产品及制备方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4615697A (en) 1983-11-14 1986-10-07 Bio-Mimetics, Inc. Bioadhesive compositions and methods of treatment therewith
NZ222698A (en) 1987-01-08 1990-02-26 Squibb & Sons Inc Bioadhesive suppository formulations comprising a medicament, water, a hydrocolloid and low melting point base
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
DK0431719T3 (da) 1989-10-31 1995-02-27 Columbia Lab Inc Vaginalt vævsbefugtende præparat
DK0500807T3 (da) 1989-10-31 2000-02-07 Columbia Lab Inc Præparat og fremgangsmåde til befugtning af væv
US5543150A (en) 1993-09-15 1996-08-06 Columbia Laboratories, Inc. Method of progesterone delivery and affect thereof
US5667492A (en) * 1994-10-07 1997-09-16 Columbia Laboratories, Inc. Use and composition of an anti-sexually transmitted diseases formulation
AT408067B (de) * 1995-03-17 2001-08-27 Gebro Pharma Gmbh Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung
US5741525A (en) 1995-10-24 1998-04-21 Marshall University Research Corporation Vaginal pharmaceutical hydrogen peroxide composition
AU714797B2 (en) 1996-06-14 2000-01-13 Mcneil-Ppc, Inc. Moisture containing compositions that are spreadable onto and adherable to biomembranes, methods of making and use thereof
IT1284874B1 (it) 1996-08-02 1998-05-22 Farmigea Spa Complessi bioadesivi di polycarbophil e farmaci antifungini o antiprotozoari azolici
US5942243A (en) 1996-11-12 1999-08-24 Polytherapeutics, Inc. Mucoadhesive compositions for administration of biologically active agents to animal tissue
AU729546B2 (en) 1996-11-14 2001-02-01 Lipomedica Ehf. Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglyceride derivatives thereof for treating of mucosa infections
DE69819748T2 (de) 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
US6159491A (en) 1999-02-12 2000-12-12 Biovector Technologies, Inc. Prolonged release bioadhesive vaginal gel dosage form
EP2275133A1 (de) 1999-02-26 2011-01-19 Novartis Vaccines and Diagnostics, Inc. Verwendung von Bioklebstoffen und Impfstoff-Adjuvantien für mucosale Verabreichung von antigenem Material
SE522260C2 (sv) 1999-10-01 2004-01-27 Ericsson Telefon Ab L M Metod, system och säkerhetsadapter för att exekvera säker dataöverföring i ett trådlöst nät
UA74168C2 (uk) 1999-10-05 2005-11-15 Коламбіа Леборетеріс (Бермуда) Лімітед Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу
CA2386422A1 (en) * 1999-10-22 2001-04-26 Lif-Hlaup Ehf. Bio-Gels Pharmaceuticals Inc. Pharmaceutical composition for treatment of mucosal epithelial ulceration and/or erosion
ATE355854T1 (de) * 2000-08-03 2007-03-15 Antares Pharma Ipl Ag Neue zusammensetzung zur transdermalen und/oder transmukosalen wirkstoffanwendung mit geeignetem therapeutischen spiegel
US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
US7709026B2 (en) * 2001-10-29 2010-05-04 Columbia Laboratories, Inc. Low concentration of peroxide for treating or preventing vaginal infections
US6967194B1 (en) * 2002-09-18 2005-11-22 Susan Matsuo Bio-identical hormones and method of use
ES2237298B1 (es) 2003-07-16 2006-11-01 Italfarmaco, S.A. Formulaciones mucoadhesivas semisolidas.

Also Published As

Publication number Publication date
EP1652535A1 (de) 2006-05-03
DE602004029369D1 (de) 2010-11-11
EP1652535B1 (de) 2010-09-29
US20060240111A1 (en) 2006-10-26
HRP20100635T1 (hr) 2010-12-31
ES2353694T3 (es) 2011-03-04
CY1110954T1 (el) 2015-06-11
JP4891765B2 (ja) 2012-03-07
EP2100612A2 (de) 2009-09-16
SI1652535T1 (sl) 2010-12-31
ES2237298A1 (es) 2005-07-16
ES2237298B1 (es) 2006-11-01
PL1652535T3 (pl) 2011-03-31
DK1652535T3 (da) 2010-11-15
WO2005007194A1 (es) 2005-01-27
JP2007528864A (ja) 2007-10-18
PT1652535E (pt) 2010-11-18
US8663688B2 (en) 2014-03-04
EP2100612A3 (de) 2010-06-02

Similar Documents

Publication Publication Date Title
ATE482723T1 (de) Halbfeste mukoadhäsive formulierungen
PT1446122E (pt) Utilizacao de flibanserina no tratamento de disturbios de desejo sexual
MA27888A1 (fr) Inhibiteurs de la kinase p38 a base d'heterocycles a 5 chainons
NO20053077D0 (no) Terapeutiske formuleringer for behandling av beta-amyloid-relaterte sykdommer.
ATE407676T1 (de) Topoisomerasehemmern zur behandlung von chirurgischen verklebungen
NO20034056D0 (no) Proliferative sykdommer
WO2006034048A8 (en) Therapeutic agents targeting the ncca-atp channel and methods of use thereof
WO2003014309A3 (en) Interleukin-1 receptors in the treatment of diseases
IL181740A0 (en) THERAPEUTIC AGENTS TARGETING THE NCca-atp CHANNEL AND METHODS OF USE THEREOF
IL172423A0 (en) Novel formulations for opioid -based treatments of pain comprising substituted 1,4-di-piperidin-4-yl-piperazine derivatives
ITBO20000453A0 (it) Apparecchiatura e procedimento per la sterilizzazione del terreno .
WO2005044200A3 (en) Methods and compositions for treating mcp-1 related pathologies
TR200800691T2 (tr) Miyelin kaybettiren hastalıkların ya da durumların tedavi yöntemi.
CY1109666T1 (el) Μεθοδος θεραπειας διαταραχων ξηροφθαλμιας και ραγοειδιτιδας
DK1713438T3 (da) Medicinsk sæbe
DE602004014787D1 (de) Anti-tumorale formulierungen mit defibrotid allein oder in kombination mit anderen antitumoralen mitteln
BR0210632A (pt) Tratamento de doença parasìtica
CY1106702T1 (el) Χρηση ενος συνδυασμου μιας πουρινης και ενος παραγοντα δοτη μονοξειδιου του αζωτου για την προληψη ή την αγωγη γενετησιων δυσλειτουργιων
IT1318509B1 (it) Polimeri reticolati, utili per uso farmaceutico, medicale e cosmetico.
WO2002051404A8 (fr) Compositions orales
RU2000104127A (ru) Штамм bacillus subtilis x-15, используемый для профилактики и лечения эндометритов у коров
WO2004006900A3 (en) Sulphydryl compounds in combination with sulphone or sulphnamide conpounds for use in microbial inflammatory diseases
ITBO20000360A0 (it) Apparecchiatura di elettrostimolazione del corpo umano .
ES2159479A1 (es) Nuevos indazoles como inhibidores de la ciclooxigenasa-ii
IT1307903B1 (it) Unguento ad azione terapeutica ed antisettica del derma animale,particolarmente a localizzazione podalica.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1652535

Country of ref document: EP