CY1106155T1 - Χρηση παραγωγων 3-βενζολοφαινυλοξικων οξεων για την αντιμετωπιση διαταραχων του αμφιβληστροειδους - Google Patents
Χρηση παραγωγων 3-βενζολοφαινυλοξικων οξεων για την αντιμετωπιση διαταραχων του αμφιβληστροειδουςInfo
- Publication number
- CY1106155T1 CY1106155T1 CY20061101289T CY061101289T CY1106155T1 CY 1106155 T1 CY1106155 T1 CY 1106155T1 CY 20061101289 T CY20061101289 T CY 20061101289T CY 061101289 T CY061101289 T CY 061101289T CY 1106155 T1 CY1106155 T1 CY 1106155T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- disorders
- benzophenylacetic
- amphiblistroid
- acid derivatives
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 208000017442 Retinal disease Diseases 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- QEFAQIPZVLVERP-UHFFFAOYSA-N nepafenac Chemical compound NC(=O)CC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1N QEFAQIPZVLVERP-UHFFFAOYSA-N 0.000 abstract 1
- 229960001002 nepafenac Drugs 0.000 abstract 1
- 230000000626 neurodegenerative effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Περιγράφεται η χρήση 3-βενζολοφαινυλοξικών οξέων και παραγώγων, συμπεριλαμβανομένου του nepafenac, για την αντιμετώπιση νευροεκφυλιστικών αμφιβληστροειδικών διαταραχών.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22513200P | 2000-08-14 | 2000-08-14 | |
PCT/US2001/025319 WO2002013805A2 (en) | 2000-08-14 | 2001-08-13 | Method of treating neurodegenerative disorders of the retina and optic nerve head |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106155T1 true CY1106155T1 (el) | 2011-06-08 |
Family
ID=22843666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101289T CY1106155T1 (el) | 2000-08-14 | 2006-09-08 | Χρηση παραγωγων 3-βενζολοφαινυλοξικων οξεων για την αντιμετωπιση διαταραχων του αμφιβληστροειδους |
Country Status (17)
Country | Link |
---|---|
US (1) | US6638976B2 (el) |
EP (1) | EP1309322B1 (el) |
JP (1) | JP2004506010A (el) |
AR (1) | AR030346A1 (el) |
AT (1) | ATE330596T1 (el) |
AU (1) | AU8125801A (el) |
BR (1) | BR0113201A (el) |
CA (1) | CA2418059C (el) |
CY (1) | CY1106155T1 (el) |
DE (1) | DE60120990T2 (el) |
DK (1) | DK1309322T3 (el) |
ES (1) | ES2266229T3 (el) |
HK (1) | HK1057332A1 (el) |
MX (1) | MXPA03001160A (el) |
PT (1) | PT1309322E (el) |
TW (1) | TWI286933B (el) |
WO (1) | WO2002013805A2 (el) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040132773A1 (en) * | 2001-08-13 | 2004-07-08 | Gamache Daniel A | Method of treating neurodgenerative disorders of the retina and optic nerve head |
AU2004249167A1 (en) * | 2003-06-13 | 2004-12-29 | Alcon, Inc. | Formulations of non-steroidal anti-inflammatory agents to treat pathologic ocular angiogenesis |
US20050009910A1 (en) * | 2003-07-10 | 2005-01-13 | Allergan, Inc. | Delivery of an active drug to the posterior part of the eye via subconjunctival or periocular delivery of a prodrug |
TWI358290B (en) | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
CA2607014A1 (en) * | 2005-05-10 | 2006-11-16 | Alcon, Inc. | Suspension formulations of nepafenac and other ophthalmic drugs for topical treatment of ophthalmic disorders |
US20060257487A1 (en) * | 2005-05-10 | 2006-11-16 | Alcon, Inc. | Suspension formulations of nepafenac and other ophthalmic drugs for topical treatment of ophthalmic disorders |
US9370444B2 (en) | 2010-10-12 | 2016-06-21 | Emmett T. Cunningham, JR. | Subconjunctival conformer device and uses thereof |
US8915877B2 (en) | 2010-10-12 | 2014-12-23 | Emmett T. Cunningham, JR. | Glaucoma drainage device and uses thereof |
RU2458656C1 (ru) * | 2011-06-17 | 2012-08-20 | Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" | Способ лечения оперированного незакрывшегося макулярного отверстия |
EP3013790A1 (en) | 2013-06-27 | 2016-05-04 | Mylan Laboratories Ltd. | Process for the preparation of nepafenac |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1226344A (el) | 1967-07-31 | 1971-03-24 | ||
SE400966B (sv) | 1975-08-13 | 1978-04-17 | Robins Co Inc A H | Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror |
US4313949A (en) | 1979-09-26 | 1982-02-02 | A. H. Robins Company, Inc. | Method of producing an inhibitory effect on blood platelet aggregation |
US4254146A (en) * | 1979-10-18 | 1981-03-03 | A. H. Robins Company, Inc. | 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters |
IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
DE3026402A1 (de) * | 1980-07-11 | 1982-02-04 | Syntex Corp., Palo Alto, Calif. | Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen |
US4503073A (en) * | 1981-01-07 | 1985-03-05 | A. H. Robins Company, Incorporated | 2-Amino-3-(alkylthiobenzoyl)-phenylacetic acids |
IL64724A0 (en) | 1981-02-17 | 1982-03-31 | Robins Co Inc A H | 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them |
US4454151A (en) | 1982-03-22 | 1984-06-12 | Syntex (U.S.A.) Inc. | Use of pyrrolo pyrroles in treatment of ophthalmic diseases |
US4568695A (en) * | 1983-12-07 | 1986-02-04 | A. H. Robins Company, Incorporated | 2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor |
US4851443A (en) | 1985-03-14 | 1989-07-25 | Smith Kline Dauelsberg, Gmbh | Carboxylic acid amides, compositions and medical use thereof |
DE3668450D1 (de) | 1985-03-14 | 1990-03-01 | Smithkline Dauelsberg | 5-aminosalicylsaeurederivate von nicht-steroidalen entzuendungshemmenden sauren. |
US4683242A (en) * | 1985-10-28 | 1987-07-28 | A. H. Robins Company, Incorporated | Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters |
DK406686D0 (da) | 1986-08-26 | 1986-08-26 | Hans Bundgaard | Carboxylsyrederivater |
US4910225A (en) | 1988-01-27 | 1990-03-20 | Senju Pharmaceutical Co., Ltd. | Locally administrable therapeutic composition for inflammatory disease |
US5314909A (en) | 1993-03-17 | 1994-05-24 | Merck & Co., Inc. | Use of non-steroidal antiiflammatory agents in macular degeneration |
JP3396953B2 (ja) | 1994-05-10 | 2003-04-14 | 千寿製薬株式会社 | 網膜疾患予防・治療剤 |
US5475034A (en) | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
US5643943A (en) * | 1994-12-23 | 1997-07-01 | Alcon Laboratories, Inc. | Systemic administration of esters and amides of antioxidants which may be used as antioxidant prodrug therapy for oxidative and inflammatory pathogenesis |
US5811446A (en) * | 1997-04-18 | 1998-09-22 | Cytos Pharmaceuticals Llc | Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor |
US6025353A (en) | 1997-11-19 | 2000-02-15 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents |
US6066671A (en) * | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
CN1227008C (zh) | 1999-01-07 | 2005-11-16 | 范德比尔特大学 | 将非cox-2选择性抑制剂的cox抑制化合物转化成为cox-2选择性抑制剂的衍生物的方法 |
US6555540B1 (en) | 1999-06-30 | 2003-04-29 | Pfizer Inc | Combinations of aldose reductase inhibitors and selective cyclooxygenase-2 inhibitors |
US6426341B1 (en) | 1999-06-30 | 2002-07-30 | Pfizer Inc. | Treatment for diabetic complications |
US6413965B1 (en) | 1999-06-30 | 2002-07-02 | Pfizer Inc. | Compositions and treatment for diabetic complications |
US6416777B1 (en) | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
-
2001
- 2001-08-10 AR ARP010103847A patent/AR030346A1/es not_active Application Discontinuation
- 2001-08-13 DK DK01959734T patent/DK1309322T3/da active
- 2001-08-13 MX MXPA03001160A patent/MXPA03001160A/es active IP Right Grant
- 2001-08-13 TW TW090119751A patent/TWI286933B/zh not_active IP Right Cessation
- 2001-08-13 JP JP2002518951A patent/JP2004506010A/ja active Pending
- 2001-08-13 BR BRPI0113201-6A patent/BR0113201A/pt not_active Application Discontinuation
- 2001-08-13 DE DE60120990T patent/DE60120990T2/de not_active Expired - Lifetime
- 2001-08-13 AU AU8125801A patent/AU8125801A/xx not_active Withdrawn
- 2001-08-13 EP EP01959734A patent/EP1309322B1/en not_active Expired - Lifetime
- 2001-08-13 WO PCT/US2001/025319 patent/WO2002013805A2/en active IP Right Grant
- 2001-08-13 ES ES01959734T patent/ES2266229T3/es not_active Expired - Lifetime
- 2001-08-13 AT AT01959734T patent/ATE330596T1/de active
- 2001-08-13 CA CA002418059A patent/CA2418059C/en not_active Expired - Fee Related
- 2001-08-13 US US09/929,704 patent/US6638976B2/en not_active Expired - Lifetime
- 2001-08-13 PT PT01959734T patent/PT1309322E/pt unknown
-
2003
- 2003-11-14 HK HK03108334A patent/HK1057332A1/xx not_active IP Right Cessation
-
2006
- 2006-09-08 CY CY20061101289T patent/CY1106155T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE60120990T2 (de) | 2007-03-15 |
CA2418059C (en) | 2009-12-22 |
EP1309322A2 (en) | 2003-05-14 |
PT1309322E (pt) | 2006-11-30 |
MXPA03001160A (es) | 2004-08-02 |
ATE330596T1 (de) | 2006-07-15 |
EP1309322B1 (en) | 2006-06-21 |
AU8125801A (en) | 2002-02-25 |
WO2002013805A3 (en) | 2002-05-30 |
ES2266229T3 (es) | 2007-03-01 |
AR030346A1 (es) | 2003-08-20 |
HK1057332A1 (en) | 2004-04-02 |
DK1309322T3 (da) | 2006-10-23 |
US6638976B2 (en) | 2003-10-28 |
DE60120990D1 (de) | 2006-08-03 |
TWI286933B (en) | 2007-09-21 |
BR0113201A (pt) | 2006-05-09 |
WO2002013805A2 (en) | 2002-02-21 |
JP2004506010A (ja) | 2004-02-26 |
US20020049255A1 (en) | 2002-04-25 |
CA2418059A1 (en) | 2002-02-21 |
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