CY1110829T1 - Συνδυασμοι περιλαμβανοντες αντιμουσκαρινικους παραγοντες και αναστολεις pde4 - Google Patents

Συνδυασμοι περιλαμβανοντες αντιμουσκαρινικους παραγοντες και αναστολεις pde4

Info

Publication number
CY1110829T1
CY1110829T1 CY20101100905T CY101100905T CY1110829T1 CY 1110829 T1 CY1110829 T1 CY 1110829T1 CY 20101100905 T CY20101100905 T CY 20101100905T CY 101100905 T CY101100905 T CY 101100905T CY 1110829 T1 CY1110829 T1 CY 1110829T1
Authority
CY
Cyprus
Prior art keywords
antimuscarinating
agents
pde4 inhibitors
containers including
anion
Prior art date
Application number
CY20101100905T
Other languages
Greek (el)
English (en)
Inventor
Escardo Jordi Gras
Calvo Jesus Llenas
Hamish Ryder
Diaz Pio Orviz
Original Assignee
Almirall, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES200401312A external-priority patent/ES2257152B1/es
Application filed by Almirall, S.A. filed Critical Almirall, S.A.
Publication of CY1110829T1 publication Critical patent/CY1110829T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CY20101100905T 2004-05-31 2010-10-11 Συνδυασμοι περιλαμβανοντες αντιμουσκαρινικους παραγοντες και αναστολεις pde4 CY1110829T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
ES200401312A ES2257152B1 (es) 2004-05-31 2004-05-31 Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
EP2005001969 2005-02-24
GB2005000722 2005-02-25
GB2005000740 2005-02-25
EP07019646A EP1891974B1 (en) 2004-05-31 2005-05-31 Combinations comprising antimuscarinic agents and PDE4 inhibitors

Publications (1)

Publication Number Publication Date
CY1110829T1 true CY1110829T1 (el) 2015-06-10

Family

ID=34968792

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100905T CY1110829T1 (el) 2004-05-31 2010-10-11 Συνδυασμοι περιλαμβανοντες αντιμουσκαρινικους παραγοντες και αναστολεις pde4

Country Status (21)

Country Link
US (2) US20110224177A1 (forum.php)
EP (5) EP2210614A1 (forum.php)
JP (1) JP2012211183A (forum.php)
AT (3) ATE419011T1 (forum.php)
AU (3) AU2005247104B2 (forum.php)
BE (1) BE2015C012I2 (forum.php)
CA (3) CA2568571C (forum.php)
CY (1) CY1110829T1 (forum.php)
DE (3) DE602005022499D1 (forum.php)
DK (2) DK1905451T3 (forum.php)
ES (2) ES2336144T3 (forum.php)
HR (3) HRP20090106T3 (forum.php)
IL (3) IL179685A (forum.php)
MX (3) MXPA06013850A (forum.php)
NZ (3) NZ551670A (forum.php)
PL (2) PL1905451T3 (forum.php)
PT (3) PT1765404E (forum.php)
RS (3) RS50786B (forum.php)
RU (3) RU2385156C2 (forum.php)
SI (3) SI1765404T1 (forum.php)
WO (3) WO2005115465A1 (forum.php)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
JPWO2006085689A1 (ja) * 2005-02-10 2008-06-26 オンコリスバイオファーマ株式会社 テロメライシン併用抗癌剤
WO2008102128A2 (en) * 2007-02-19 2008-08-28 Cipla Limited Pharmaceutical combinations of at least two bronchodilators or of a bronchodilator with a corticosteroid
EP2080523A1 (en) * 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Compositions comprising an antimuscarinic and a long-acting beta-agonist
EP2080508A1 (en) * 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Dry powder formulation comprising an anticholinergic drug
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
GB0811100D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination
GB0814728D0 (en) * 2008-08-12 2008-09-17 Argenta Discovery Ltd New combination
WO2010097114A1 (en) * 2009-02-26 2010-09-02 Glaxo Group Limited Novel combination of therapeutic agents
DK3578169T3 (da) 2009-02-26 2024-07-22 Glaxo Group Ltd Farmaceutiske formuleringer omfattende 4-{(1R)-2-[(6-{2-[(2,6-dichlorbenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
CN101885731A (zh) 2009-05-14 2010-11-17 天津和美生物技术有限公司 噻吩衍生物
GB0921075D0 (en) * 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
CN104470503A (zh) 2012-04-13 2015-03-25 葛兰素史克知识产权开发有限公司 聚集粒子
GB201222679D0 (en) 2012-12-17 2013-01-30 Glaxo Group Ltd Pharmaceutical combination products
WO2014140647A1 (en) 2013-03-15 2014-09-18 Verona Pharma Plc Drug combination
GB201308933D0 (en) * 2013-05-17 2013-07-03 Diurnal Ltd Paediatric composition
EP3591053A1 (en) * 2013-07-05 2020-01-08 Bioneer Corporation Respiratory disease-related gene specific sirna, double-helical oligo rna structure containing sirna, compositon containing same for preventing or treating respiratory disease
TW201542207A (zh) * 2013-10-03 2015-11-16 Otsuka Pharma Co Ltd 嚴重氣喘治療劑

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT7920688U1 (it) 1979-02-05 1980-08-05 Chiesi Paolo Inalatore per sostanze medicamentose pulverulente, con combinata funzione di dosatore
EP0069715B1 (en) 1981-07-08 1986-11-05 Aktiebolaget Draco Powder inhalator
US4570630A (en) 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
FI69963C (fi) 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
DE3927170A1 (de) 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
IT1237118B (it) 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
US5201308A (en) 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
GB9004781D0 (en) 1990-03-02 1990-04-25 Glaxo Group Ltd Device
SG45171A1 (en) 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
GB9015522D0 (en) 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
WO1992003175A1 (en) 1990-08-11 1992-03-05 Fisons Plc Inhalation device
DE4027391A1 (de) 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
ATE164525T1 (de) 1990-09-26 1998-04-15 Pharmachemie Bv Inhalator mit einem reservoir für mehrere dosierte inhalationsmittel, mit transportvorrichtung und mit wirbelkammer
GB9026025D0 (en) 1990-11-29 1991-01-16 Boehringer Ingelheim Kg Inhalation device
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
DE4239402A1 (de) 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
MY115140A (en) 1992-12-18 2003-04-30 Schering Corp Inhaler for powdered medications
US5837699A (en) * 1994-01-27 1998-11-17 Schering Corporation Use of mometasone furoate for treating upper airway passage diseases
PL180901B1 (pl) 1995-04-14 2001-04-30 Glaxo Wellcome Inc Inhalator z dozymetrem
PT837710E (pt) 1995-06-21 2002-05-31 Sofotec Gmbh & Co Kg Cartucho de po farmaceutico com dispositivo de doseamento integrado e inalador para medicamentos em po
DE19528145A1 (de) * 1995-08-01 1997-02-06 Boehringer Ingelheim Kg Neue Arzneimittel und ihre Verwendung
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB0009592D0 (en) 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
GB0009606D0 (en) 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic combinations
GB0009583D0 (en) 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory formulations
GB0009605D0 (en) 2000-04-18 2000-06-07 Glaxo Group Ltd Medicaments
AU2001290075A1 (en) * 2000-09-22 2002-04-02 Glaxo Group Limited Novel alkanoic acid derivatives
DE10062712A1 (de) 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
WO2002036106A2 (de) 2000-10-31 2002-05-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue arzneimittelkompositionen auf der basis von anticholingergika und corticosteroiden
DE10056104A1 (de) * 2000-11-13 2002-05-23 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Tiotropiumsalzen und Salzen des Salmeterols
EP1353919B1 (en) * 2000-12-28 2006-07-26 Almirall Prodesfarma AG Novel quinuclidine derivatives and medicinal compositions containing the same
ES2276942T3 (es) * 2001-05-25 2007-07-01 BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG Combinacion de un inhibidor de pde4 y tiotropio o un derivado del mismo para tratar vias respiratorias obstructivas y otras enfermedades inflamatorias.
DE10130371A1 (de) * 2001-06-23 2003-01-02 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika
ES2206021B1 (es) * 2002-04-16 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de pirrolidinio.
ES2195785B1 (es) 2002-05-16 2005-03-16 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
KR20100137026A (ko) * 2002-05-17 2010-12-29 노파르티스 아게 레닌 억제제, 칼슘 채널 차단제 및 이뇨제를 포함하는 약제학적 조성물
MXPA04012410A (es) * 2002-06-12 2005-10-19 Epigenesis Pharmaceuticals Inc Composiciones, formulaciones y equipo para el tratamiento de enfermedades pulmonares y respiratorias con deshidroepiandrosteronas, esteroides y agentes antimuscarinicos.
ES2211315B1 (es) 2002-11-12 2005-10-16 Almirall Prodesfarma, S.A. Nuevos compuestos triciclicos.
ES2211344B1 (es) 2002-12-26 2005-10-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
PE20040950A1 (es) * 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
WO2004084897A1 (en) * 2003-03-28 2004-10-07 Altana Pharma Ag Synergistic combination comprising roflumilast and an anticholinergic agent selected from ipratropium, oxitropium and tiotropium salts for the treatment of respiratory diseases
DK1610787T3 (da) * 2003-03-28 2008-06-02 Nycomed Gmbh Synergistisk kombination der omfatter roflumilast og et antikolinergt middel der er valgt blandt tiotropiumsalte til behandling af respiratoriske sygdomme
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.

Also Published As

Publication number Publication date
CA2569074C (en) 2012-12-18
HK1096605A1 (en) 2007-06-08
PL1905451T3 (pl) 2010-05-31
ATE454904T1 (de) 2010-01-15
ES2317245T3 (es) 2009-04-16
RU2379033C2 (ru) 2010-01-20
DK1905451T3 (da) 2010-05-10
AU2005247104B2 (en) 2010-11-11
NZ551670A (en) 2010-07-30
AU2005247106B2 (en) 2010-11-11
AU2005247105B2 (en) 2010-11-11
ES2336144T3 (es) 2010-04-08
US20110224177A1 (en) 2011-09-15
HRP20090106T3 (en) 2009-03-31
CA2569074A1 (en) 2005-12-08
BE2015C012I2 (forum.php) 2024-10-08
CA2568571C (en) 2012-12-18
JP2012211183A (ja) 2012-11-01
CA2568568C (en) 2012-12-18
HRP20100490T1 (hr) 2010-10-31
SI1765404T1 (sl) 2009-04-30
EP1905451B1 (en) 2010-01-13
ATE474601T1 (de) 2010-08-15
SI1891974T1 (sl) 2010-11-30
MXPA06013846A (es) 2007-03-01
AU2005247104A1 (en) 2005-12-08
RS50786B (sr) 2010-08-31
IL179685A0 (en) 2007-05-15
EP2210614A1 (en) 2010-07-28
RU2006146673A (ru) 2008-07-20
NZ551666A (en) 2010-07-30
IL179690A0 (en) 2007-05-15
DE602005022499D1 (de) 2010-09-02
CA2568568A1 (en) 2005-12-08
SI1905451T1 (sl) 2010-05-31
DE602005018969D1 (de) 2010-03-04
NZ551669A (en) 2010-07-30
US20130196961A1 (en) 2013-08-01
DK1891974T3 (da) 2010-11-08
RU2404772C2 (ru) 2010-11-27
EP1761279A1 (en) 2007-03-14
PT1891974E (pt) 2010-09-27
EP1905451A1 (en) 2008-04-02
PT1765404E (pt) 2009-03-31
RS51422B (sr) 2011-02-28
WO2005115465A1 (en) 2005-12-08
WO2005115463A1 (en) 2005-12-08
RU2006147269A (ru) 2008-07-20
CA2568571A1 (en) 2005-12-08
RS51206B (sr) 2010-12-31
IL179690A (en) 2012-10-31
EP1891974A1 (en) 2008-02-27
IL179686A0 (en) 2007-05-15
WO2005115464A1 (en) 2005-12-08
RU2006146813A (ru) 2008-07-20
MXPA06013849A (es) 2007-03-01
MXPA06013850A (es) 2007-03-02
EP1765405A1 (en) 2007-03-28
PT1905451E (pt) 2010-03-31
PL1891974T3 (pl) 2010-12-31
AU2005247105A1 (en) 2005-12-08
DE602005012102D1 (de) 2009-02-12
HRP20100104T1 (hr) 2010-04-30
ATE419011T1 (de) 2009-01-15
IL179685A (en) 2012-01-31
EP1891974B1 (en) 2010-07-21
RU2385156C2 (ru) 2010-03-27
AU2005247106A1 (en) 2005-12-08

Similar Documents

Publication Publication Date Title
CY1110829T1 (el) Συνδυασμοι περιλαμβανοντες αντιμουσκαρινικους παραγοντες και αναστολεις pde4
CY1110798T1 (el) Συνδυασμοι περιλαμβανοντες αντιμουσκαρινικους παραγοντες και αναστολεις pde4
BRPI0415361A (pt) antagonistas do receptor muscarìnico de acetilcolina
CY1116312T1 (el) Κρυσταλλος αλατος 4-(3-χλωρο-4-(κυκλοπροπυλ αμινοκαρβονυλ)αμινο-φαινοξυ)-7-μεθοξυ-6-κινολινοκαρβοξαμιδιου ή διαλυτωματος αυτου και διεργασιες για την παρασκευη αυτων
CY1108725T1 (el) Συνδυασμος ανταγωνιστου-nmda και αναστολεων ακετυλοχολινεστερασης δια την θεραπειαν της νοσου alzheimer
UA95768C2 (ru) Антагонисты мускариновых рецепторов ацетилхолина
ECSP034773A (es) Pirazolopirimmidinas como agentes terapeuticos
EP3569601A3 (en) N-(phenylsulfonyl)benzamides and related compounds as bcl-2 inhibitors
NO20031672D0 (no) Aza- og polyaza-naftalenylkarboksamider for anvendelse som HIV-integraseinhibitorer
CY2014033I1 (el) Παραγωγα κινολινης και η χρηση τους ως μυκοβακτηριακων αναστολεων
MX374412B (es) Una composición que comprende un inhibidor de pde3/pde4 o una sal de adición del mismo y un antagonista del receptor muscarínico.
ECSP034765A (es) Derivados de bipiperidinilo y su uso como inhibidores de receptores de quimiocina
CY1111983T1 (el) Φαρμακευτικη συνθεση και μεθοδος χρησης αντιμυκητιακου παραγοντα σε συνδυασμο
MXPA05007609A (es) Antagonista de un receptor sensible al calcio.
BR0313385A (pt) Derivados de pirimidina-2,4-diona como inibidores de metaloproteinase da matriz
UY27424A1 (es) Agentes antidiabéticos
DK1667668T3 (da) Alfabeta3 og altabeta6-integrinantagonister som antifibrotiske midler
HRP20080313A2 (en) Methods for improving the pharmacokinetics of hiv integrase inhibitors
BRPI0415281A (pt) antagonistas de receptor de acetilcolina muscarìnico
WO2009106599A3 (en) Substituted piperidines as therapeutic compounds
DE60122559D1 (de) Indolderivate als pde5-inhibitoren
EA200601592A1 (ru) Фармацевтическая композиция, содержащая ингибитор pde4 или pde3/4 и антагонист гистаминового рецептора
DE602004013937D1 (de) Kombinationspräparate zur verhinderung von schlagand einen atii antagonisten enthalten
PL369736A1 (en) New medicinal compositions on the basis of anticholinergic agents and egfr kinase inhibitors
TW200738635A (en) New salt