DK1667668T3 - Alfabeta3 og altabeta6-integrinantagonister som antifibrotiske midler - Google Patents
Alfabeta3 og altabeta6-integrinantagonister som antifibrotiske midlerInfo
- Publication number
- DK1667668T3 DK1667668T3 DK04765296T DK04765296T DK1667668T3 DK 1667668 T3 DK1667668 T3 DK 1667668T3 DK 04765296 T DK04765296 T DK 04765296T DK 04765296 T DK04765296 T DK 04765296T DK 1667668 T3 DK1667668 T3 DK 1667668T3
- Authority
- DK
- Denmark
- Prior art keywords
- altabeta6
- alphabeta3
- integrin antagonists
- antifibrotic agents
- antifibrotic
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title 1
- 230000003510 anti-fibrotic effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 102000006495 integrins Human genes 0.000 title 1
- 108010044426 integrins Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03022048 | 2003-10-01 | ||
| PCT/EP2004/010396 WO2005039547A1 (en) | 2003-10-01 | 2004-09-16 | Alfavbeta3 and alfavbeta6 integrin antagonists as antifibrotic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1667668T3 true DK1667668T3 (da) | 2008-09-15 |
Family
ID=34486055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04765296T DK1667668T3 (da) | 2003-10-01 | 2004-09-16 | Alfabeta3 og altabeta6-integrinantagonister som antifibrotiske midler |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20070117849A1 (da) |
| EP (1) | EP1667668B1 (da) |
| JP (1) | JP4912881B2 (da) |
| KR (1) | KR101191068B1 (da) |
| CN (1) | CN100462068C (da) |
| AR (1) | AR045960A1 (da) |
| AT (1) | ATE399542T1 (da) |
| AU (1) | AU2004283413B2 (da) |
| BR (1) | BRPI0414927A (da) |
| CA (1) | CA2540730C (da) |
| DE (1) | DE602004014795D1 (da) |
| DK (1) | DK1667668T3 (da) |
| ES (1) | ES2308227T3 (da) |
| MX (1) | MXPA06003477A (da) |
| PL (1) | PL1667668T3 (da) |
| RU (1) | RU2388472C2 (da) |
| WO (1) | WO2005039547A1 (da) |
| ZA (1) | ZA200603427B (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2287199B1 (en) | 2002-03-13 | 2017-08-02 | Biogen MA Inc. | Anti-alpha V beta 6 antibodies |
| GB0722650D0 (en) * | 2007-11-19 | 2007-12-27 | Ge Healthcare Ltd | Novel imaging method |
| CN101497656B (zh) * | 2009-03-09 | 2012-08-15 | 东南大学 | 与整合素αvβ3具有高结合活性的多肽及其应用 |
| GB0922014D0 (en) | 2009-12-17 | 2010-02-03 | Ge Healthcare Ltd | Novel integrin binders |
| EP2831104B1 (en) * | 2012-03-29 | 2021-04-21 | Biogen MA Inc. | Biomarkers for use in integrin therapy applications |
| US8716226B2 (en) | 2012-07-18 | 2014-05-06 | Saint Louis University | 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists |
| JP6215324B2 (ja) | 2012-07-18 | 2017-10-18 | セントルイス ユニバーシティ | インテグリンアンタゴニストとしてのβアミノ酸誘導体 |
| PT2953948T (pt) | 2013-02-07 | 2017-12-12 | Scifluor Life Sciences Inc | Antagonistas de integrina fluorada |
| WO2014144466A1 (en) | 2013-03-15 | 2014-09-18 | Biogen Idec Ma Inc. | Anti-alpha v beta 6 antibodies and uses thereof |
| US10035860B2 (en) | 2013-03-15 | 2018-07-31 | Biogen Ma Inc. | Anti-alpha V beta 6 antibodies and uses thereof |
| US9790222B2 (en) | 2015-02-19 | 2017-10-17 | Scifluor Life Sciences, Inc. | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof |
| CA3008023A1 (en) | 2015-12-30 | 2017-07-06 | Saint Louis University | Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists |
| MA46746A (fr) * | 2016-11-08 | 2019-09-18 | Bristol Myers Squibb Co | Amides d'azole et amines en tant qu'inhibiteurs d'intégrine alpha v |
| HUE053620T2 (hu) * | 2016-11-08 | 2021-07-28 | Bristol Myers Squibb Co | Pirrol amidok mint alfa-V integrin inhibitorok |
| EP3551046B1 (en) | 2016-12-07 | 2023-07-19 | Biora Therapeutics, Inc. | Gastrointestinal tract detection methods, devices and systems |
| TW201834710A (zh) | 2016-12-14 | 2018-10-01 | 美商寶珍那提公司 | 以整合素抑制劑治療胃腸道疾病 |
| EP3810085A1 (en) | 2018-06-20 | 2021-04-28 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| KR20210095165A (ko) | 2018-11-19 | 2021-07-30 | 프로제너티, 인크. | 바이오의약품으로 질환을 치료하기 위한 방법 및 디바이스 |
| CN115666704A (zh) | 2019-12-13 | 2023-01-31 | 比奥拉治疗股份有限公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2371824A1 (en) * | 1999-02-20 | 2000-08-24 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | .beta.-alanine derivatives |
| DE19933173A1 (de) * | 1999-07-15 | 2001-01-18 | Merck Patent Gmbh | Cyclische Peptidderivate als Inhibitoren des Integrins alpha¶v¶beta¶6¶ |
| DE10006139A1 (de) * | 2000-02-11 | 2001-08-16 | Merck Patent Gmbh | Indol-3-yl-Derivate |
| DE10063173A1 (de) * | 2000-12-18 | 2002-06-20 | Merck Patent Gmbh | Harnstoff- und Urethanderivate |
| CA2439852A1 (en) * | 2001-03-02 | 2002-09-12 | Christine Dingivan | Methods of preventing or treating inflammatory or autoimmune disorders by administering integrin alphav beta3 antagonists |
| DE10112771A1 (de) * | 2001-03-16 | 2002-09-26 | Merck Patent Gmbh | Inhibitoren des Integrins alpha¶v¶beta¶6¶ |
-
2004
- 2004-09-16 PL PL04765296T patent/PL1667668T3/pl unknown
- 2004-09-16 ES ES04765296T patent/ES2308227T3/es not_active Expired - Lifetime
- 2004-09-16 MX MXPA06003477A patent/MXPA06003477A/es active IP Right Grant
- 2004-09-16 CA CA2540730A patent/CA2540730C/en not_active Expired - Fee Related
- 2004-09-16 KR KR1020067006141A patent/KR101191068B1/ko not_active IP Right Cessation
- 2004-09-16 WO PCT/EP2004/010396 patent/WO2005039547A1/en active IP Right Grant
- 2004-09-16 AT AT04765296T patent/ATE399542T1/de active
- 2004-09-16 JP JP2006529991A patent/JP4912881B2/ja not_active Expired - Fee Related
- 2004-09-16 US US10/574,215 patent/US20070117849A1/en not_active Abandoned
- 2004-09-16 EP EP04765296A patent/EP1667668B1/en not_active Expired - Lifetime
- 2004-09-16 RU RU2006114395/15A patent/RU2388472C2/ru not_active IP Right Cessation
- 2004-09-16 CN CNB2004800286709A patent/CN100462068C/zh not_active Expired - Fee Related
- 2004-09-16 AU AU2004283413A patent/AU2004283413B2/en not_active Ceased
- 2004-09-16 DK DK04765296T patent/DK1667668T3/da active
- 2004-09-16 DE DE602004014795T patent/DE602004014795D1/de not_active Expired - Lifetime
- 2004-09-16 BR BRPI0414927-0A patent/BRPI0414927A/pt active Search and Examination
- 2004-10-01 AR ARP040103571A patent/AR045960A1/es not_active Application Discontinuation
-
2006
- 2006-04-28 ZA ZA200603427A patent/ZA200603427B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR045960A1 (es) | 2005-11-16 |
| ATE399542T1 (de) | 2008-07-15 |
| WO2005039547A1 (en) | 2005-05-06 |
| US20070117849A1 (en) | 2007-05-24 |
| CN1863520A (zh) | 2006-11-15 |
| CA2540730C (en) | 2012-08-21 |
| EP1667668B1 (en) | 2008-07-02 |
| KR20060090818A (ko) | 2006-08-16 |
| ZA200603427B (en) | 2007-09-26 |
| RU2388472C2 (ru) | 2010-05-10 |
| RU2006114395A (ru) | 2007-11-27 |
| PL1667668T3 (pl) | 2008-10-31 |
| AU2004283413B2 (en) | 2010-09-02 |
| EP1667668A1 (en) | 2006-06-14 |
| ES2308227T3 (es) | 2008-12-01 |
| MXPA06003477A (es) | 2006-06-05 |
| BRPI0414927A (pt) | 2006-11-07 |
| JP4912881B2 (ja) | 2012-04-11 |
| DE602004014795D1 (de) | 2008-08-14 |
| CA2540730A1 (en) | 2005-05-06 |
| CN100462068C (zh) | 2009-02-18 |
| AU2004283413A1 (en) | 2005-05-06 |
| KR101191068B1 (ko) | 2012-10-15 |
| JP2007507440A (ja) | 2007-03-29 |
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