CY1109487T1 - Ανταγωνιστες τυπου ουριας του υποδοχεα p2y1 χρησιμοι στην αγωγη θρομβωτικων καταστασεων - Google Patents

Ανταγωνιστες τυπου ουριας του υποδοχεα p2y1 χρησιμοι στην αγωγη θρομβωτικων καταστασεων

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Publication number
CY1109487T1
CY1109487T1 CY20091101048T CY091101048T CY1109487T1 CY 1109487 T1 CY1109487 T1 CY 1109487T1 CY 20091101048 T CY20091101048 T CY 20091101048T CY 091101048 T CY091101048 T CY 091101048T CY 1109487 T1 CY1109487 T1 CY 1109487T1
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CY
Cyprus
Prior art keywords
receptor
treatment
urea
antagonists useful
thrombotic conditions
Prior art date
Application number
CY20091101048T
Other languages
English (en)
Inventor
Huji Tuerdi
Hannguang J. Chao
Jennifer X. Qiao
Tammy C. Wang
Timur Gungor
Original Assignee
Bristol-Myers Squibb Company
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35169638&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1109487(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of CY1109487T1 publication Critical patent/CY1109487T1/el

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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

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  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Η παρούσα εφεύρεση παρέχει νέες ουρίες που περιέχουν Ν-αρυλο ή Ν-ετεροαρυλο υποκατεστημένους ετερόκυκλους και ανάλογα αυτών, οι οποίες είναι εκλεκτικοί αναστολείς του ανθρώπινου υποδοχέα P2Y1. Η εφεύρεση επίσης προσφέρει διάφορες φαρμακευτικές συνθέσεις αυτών και μεθόδους για την αγωγή παθήσεων που αποκρίνονται σε διαμόρφωση της ενεργότητας του υποδοχέα P2Y1.
CY20091101048T 2004-05-12 2009-10-13 Ανταγωνιστες τυπου ουριας του υποδοχεα p2y1 χρησιμοι στην αγωγη θρομβωτικων καταστασεων CY1109487T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US57028804P 2004-05-12 2004-05-12
US66573505P 2005-03-28 2005-03-28
US11/126,567 US7550499B2 (en) 2004-05-12 2005-05-10 Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
PCT/US2005/016525 WO2005113537A2 (en) 2004-05-12 2005-05-11 Urea antagonists of p2y1 receptor useful in the treatment of thrombotic conditions

Publications (1)

Publication Number Publication Date
CY1109487T1 true CY1109487T1 (el) 2012-05-23

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CY20091101048T CY1109487T1 (el) 2004-05-12 2009-10-13 Ανταγωνιστες τυπου ουριας του υποδοχεα p2y1 χρησιμοι στην αγωγη θρομβωτικων καταστασεων

Country Status (17)

Country Link
US (1) US7550499B2 (el)
EP (1) EP1750704B1 (el)
JP (1) JP4795336B2 (el)
KR (1) KR20070011479A (el)
CN (2) CN1984655B (el)
AU (1) AU2005245400A1 (el)
CY (1) CY1109487T1 (el)
DE (1) DE602005015577D1 (el)
DK (1) DK1750704T3 (el)
ES (1) ES2328716T3 (el)
HR (1) HRP20090468T1 (el)
MX (1) MXPA06013024A (el)
NO (1) NO20065544L (el)
PL (1) PL1750704T3 (el)
PT (1) PT1750704E (el)
SI (1) SI1750704T1 (el)
WO (1) WO2005113537A2 (el)

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US7550499B2 (en) 2009-06-23
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JP2007537273A (ja) 2007-12-20
PT1750704E (pt) 2009-10-06
JP4795336B2 (ja) 2011-10-19
KR20070011479A (ko) 2007-01-24
MXPA06013024A (es) 2006-12-20
US20050261244A1 (en) 2005-11-24
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CN1984655A (zh) 2007-06-20
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HRP20090468T1 (hr) 2009-09-30
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