CY1108648T1 - Αναστολεας της αρωματασης σε μια δοση για την θεραπευτικη αντιμετωπιση της υπογόνιμοτήτας - Google Patents
Αναστολεας της αρωματασης σε μια δοση για την θεραπευτικη αντιμετωπιση της υπογόνιμοτήταςInfo
- Publication number
- CY1108648T1 CY1108648T1 CY20081101446T CY081101446T CY1108648T1 CY 1108648 T1 CY1108648 T1 CY 1108648T1 CY 20081101446 T CY20081101446 T CY 20081101446T CY 081101446 T CY081101446 T CY 081101446T CY 1108648 T1 CY1108648 T1 CY 1108648T1
- Authority
- CY
- Cyprus
- Prior art keywords
- woman
- fsh
- aromatase inhibitor
- inhibitor
- medicament
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 abstract 5
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 abstract 5
- 239000003814 drug Substances 0.000 abstract 5
- 229940028334 follicle stimulating hormone Drugs 0.000 abstract 5
- 229940122815 Aromatase inhibitor Drugs 0.000 abstract 4
- 239000003886 aromatase inhibitor Substances 0.000 abstract 4
- 230000016087 ovulation Effects 0.000 abstract 3
- 206010061428 decreased appetite Diseases 0.000 abstract 2
- 208000000509 infertility Diseases 0.000 abstract 2
- 230000036512 infertility Effects 0.000 abstract 2
- 231100000535 infertility Toxicity 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 208000022531 anorexia Diseases 0.000 abstract 1
- 230000000578 anorexic effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000027758 ovulation cycle Effects 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28428201P | 2001-04-17 | 2001-04-17 | |
| EP02717919A EP1383578B1 (en) | 2001-04-17 | 2002-04-17 | Single dose aromatase inhibitor for treating infertility |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108648T1 true CY1108648T1 (el) | 2014-04-09 |
Family
ID=23089583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081101446T CY1108648T1 (el) | 2001-04-17 | 2008-12-12 | Αναστολεας της αρωματασης σε μια δοση για την θεραπευτικη αντιμετωπιση της υπογόνιμοτήτας |
Country Status (32)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003247404A1 (en) * | 2002-07-02 | 2004-01-23 | Pharmacia & Upjohn Company Llc | Infertility treatment with exemestane |
| JP2006522151A (ja) | 2003-04-01 | 2006-09-28 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 不妊症におけるホスホジエステラーゼ阻害剤 |
| WO2007000056A1 (en) * | 2005-06-28 | 2007-01-04 | Casper Robert F | Aromatase inhibitors for emergency contraception |
| US20100280046A1 (en) * | 2006-01-10 | 2010-11-04 | Diobex, Inc. | Methods and Compositions for Treating Prostate Cancer, Benign Prostatic Hypertrophy, Polycystic Ovary Syndrome and Other Conditions |
| AU2011256088B2 (en) * | 2010-05-20 | 2015-03-26 | University Of Saskatchewan | Use of aromatase inhibitors for synchronizing ovulation, inducing superovulation or double ovulation and improving twinning and fertility in a mammal |
| US10004723B2 (en) | 2013-04-19 | 2018-06-26 | University Of Saskatchewan | Aromatase inhibitor-releasing intravaginal device |
| US20160022644A1 (en) * | 2014-07-22 | 2016-01-28 | Tsu-I Catherine Wang | Oral Transmucosal Compositions Including Aromatase Inhibitors for Treating Female Infertility |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4728645A (en) * | 1982-12-21 | 1988-03-01 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors |
| US4602025A (en) * | 1984-06-18 | 1986-07-22 | Eli Lilly And Company | Aromatase inhibitors |
| US4845227A (en) * | 1984-06-18 | 1989-07-04 | Eli Lilly And Company | Aromatase inhibitors from azoles |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| GB8726505D0 (en) * | 1987-11-12 | 1987-12-16 | Ici Plc | Naphtho(2 1-b)furan derivatives |
| DE4330237C2 (de) | 1993-09-02 | 1995-11-30 | Schering Ag | 1-Methylsubstituierte Androsta-1,4-dien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate |
| AU2407997A (en) * | 1996-04-30 | 1997-11-19 | Takeda Chemical Industries Ltd. | Combined use of gnrh agonist and antagonist |
| DE19622457A1 (de) | 1996-05-24 | 1997-11-27 | Schering Ag | 7alpha-(5-Methylaminopentyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha-(5-Methylaminopentyl)-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln |
| US6953774B2 (en) * | 2000-08-11 | 2005-10-11 | Applied Research Systems Ars Holding N.V. | Methods of inducing ovulation |
-
2002
- 2002-04-17 JP JP2002581041A patent/JP2004529924A/ja active Pending
- 2002-04-17 SI SI200230747T patent/SI1383578T1/sl unknown
- 2002-04-17 WO PCT/CA2002/000527 patent/WO2002083241A1/en not_active Ceased
- 2002-04-17 US US10/475,101 patent/US8008333B2/en not_active Expired - Fee Related
- 2002-04-17 BR BR0208920-3A patent/BR0208920A/pt not_active IP Right Cessation
- 2002-04-17 AU AU2002249043A patent/AU2002249043B2/en not_active Ceased
- 2002-04-17 PL PL02366744A patent/PL366744A1/xx not_active Application Discontinuation
- 2002-04-17 AT AT02717919T patent/ATE409066T1/de active
- 2002-04-17 MX MXPA03009447A patent/MXPA03009447A/es not_active Application Discontinuation
- 2002-04-17 AR ARP020101399A patent/AR034036A1/es unknown
- 2002-04-17 DE DE60229047T patent/DE60229047D1/de not_active Expired - Lifetime
- 2002-04-17 EA EA200301128A patent/EA011310B1/ru not_active IP Right Cessation
- 2002-04-17 SK SK1424-2003A patent/SK14242003A3/sk unknown
- 2002-04-17 YU YU81203A patent/YU81203A/sh unknown
- 2002-04-17 KR KR10-2003-7013484A patent/KR20040025916A/ko not_active Ceased
- 2002-04-17 PT PT02717919T patent/PT1383578E/pt unknown
- 2002-04-17 IL IL15839602A patent/IL158396A0/xx unknown
- 2002-04-17 HU HU0304003A patent/HUP0304003A2/hu unknown
- 2002-04-17 CA CA2444980A patent/CA2444980C/en not_active Expired - Fee Related
- 2002-04-17 EP EP02717919A patent/EP1383578B1/en not_active Expired - Lifetime
- 2002-04-17 DK DK02717919T patent/DK1383578T3/da active
- 2002-04-17 ES ES02717919T patent/ES2311599T3/es not_active Expired - Lifetime
- 2002-04-17 EE EEP200300505A patent/EE200300505A/xx unknown
- 2002-04-17 CZ CZ20033107A patent/CZ20033107A3/cs unknown
- 2002-04-17 NZ NZ552873A patent/NZ552873A/en not_active IP Right Cessation
- 2002-04-17 UA UA20031110268A patent/UA82648C2/uk unknown
- 2002-04-17 CN CNA028120825A patent/CN1551789A/zh active Pending
- 2002-04-17 HR HR20030839A patent/HRP20030839A2/hr not_active Application Discontinuation
-
2003
- 2003-09-23 NO NO20034246A patent/NO20034246L/no not_active Application Discontinuation
- 2003-09-26 ZA ZA200307516A patent/ZA200307516B/en unknown
- 2003-11-07 BG BG108323A patent/BG108323A/bg unknown
-
2008
- 2008-12-12 CY CY20081101446T patent/CY1108648T1/el unknown
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