DK1383578T3 - Enkeltdosis aromataseinhibitor til behandling af ufrugtbarhed - Google Patents

Enkeltdosis aromataseinhibitor til behandling af ufrugtbarhed

Info

Publication number
DK1383578T3
DK1383578T3 DK02717919T DK02717919T DK1383578T3 DK 1383578 T3 DK1383578 T3 DK 1383578T3 DK 02717919 T DK02717919 T DK 02717919T DK 02717919 T DK02717919 T DK 02717919T DK 1383578 T3 DK1383578 T3 DK 1383578T3
Authority
DK
Denmark
Prior art keywords
single dose
aromatase inhibitor
treat infertility
dose aromatase
infertility
Prior art date
Application number
DK02717919T
Other languages
Danish (da)
English (en)
Inventor
Robert F Casper
Mohamed F M Mitwally
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of DK1383578T3 publication Critical patent/DK1383578T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK02717919T 2001-04-17 2002-04-17 Enkeltdosis aromataseinhibitor til behandling af ufrugtbarhed DK1383578T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28428201P 2001-04-17 2001-04-17
PCT/CA2002/000527 WO2002083241A1 (en) 2001-04-17 2002-04-17 Single dose aromatase inhibitor for treating infertility

Publications (1)

Publication Number Publication Date
DK1383578T3 true DK1383578T3 (da) 2008-11-03

Family

ID=23089583

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02717919T DK1383578T3 (da) 2001-04-17 2002-04-17 Enkeltdosis aromataseinhibitor til behandling af ufrugtbarhed

Country Status (32)

Country Link
US (1) US8008333B2 (enExample)
EP (1) EP1383578B1 (enExample)
JP (1) JP2004529924A (enExample)
KR (1) KR20040025916A (enExample)
CN (1) CN1551789A (enExample)
AR (1) AR034036A1 (enExample)
AT (1) ATE409066T1 (enExample)
AU (1) AU2002249043B2 (enExample)
BG (1) BG108323A (enExample)
BR (1) BR0208920A (enExample)
CA (1) CA2444980C (enExample)
CY (1) CY1108648T1 (enExample)
CZ (1) CZ20033107A3 (enExample)
DE (1) DE60229047D1 (enExample)
DK (1) DK1383578T3 (enExample)
EA (1) EA011310B1 (enExample)
EE (1) EE200300505A (enExample)
ES (1) ES2311599T3 (enExample)
HR (1) HRP20030839A2 (enExample)
HU (1) HUP0304003A2 (enExample)
IL (1) IL158396A0 (enExample)
MX (1) MXPA03009447A (enExample)
NO (1) NO20034246L (enExample)
NZ (1) NZ552873A (enExample)
PL (1) PL366744A1 (enExample)
PT (1) PT1383578E (enExample)
SI (1) SI1383578T1 (enExample)
SK (1) SK14242003A3 (enExample)
UA (1) UA82648C2 (enExample)
WO (1) WO2002083241A1 (enExample)
YU (1) YU81203A (enExample)
ZA (1) ZA200307516B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003247404A1 (en) * 2002-07-02 2004-01-23 Pharmacia & Upjohn Company Llc Infertility treatment with exemestane
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
WO2007000056A1 (en) * 2005-06-28 2007-01-04 Casper Robert F Aromatase inhibitors for emergency contraception
US20100280046A1 (en) * 2006-01-10 2010-11-04 Diobex, Inc. Methods and Compositions for Treating Prostate Cancer, Benign Prostatic Hypertrophy, Polycystic Ovary Syndrome and Other Conditions
AU2011256088B2 (en) * 2010-05-20 2015-03-26 University Of Saskatchewan Use of aromatase inhibitors for synchronizing ovulation, inducing superovulation or double ovulation and improving twinning and fertility in a mammal
US10004723B2 (en) 2013-04-19 2018-06-26 University Of Saskatchewan Aromatase inhibitor-releasing intravaginal device
US20160022644A1 (en) * 2014-07-22 2016-01-28 Tsu-I Catherine Wang Oral Transmucosal Compositions Including Aromatase Inhibitors for Treating Female Infertility

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728645A (en) * 1982-12-21 1988-03-01 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
US4602025A (en) * 1984-06-18 1986-07-22 Eli Lilly And Company Aromatase inhibitors
US4845227A (en) * 1984-06-18 1989-07-04 Eli Lilly And Company Aromatase inhibitors from azoles
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
GB8726505D0 (en) * 1987-11-12 1987-12-16 Ici Plc Naphtho(2 1-b)furan derivatives
DE4330237C2 (de) 1993-09-02 1995-11-30 Schering Ag 1-Methylsubstituierte Androsta-1,4-dien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
AU2407997A (en) * 1996-04-30 1997-11-19 Takeda Chemical Industries Ltd. Combined use of gnrh agonist and antagonist
DE19622457A1 (de) 1996-05-24 1997-11-27 Schering Ag 7alpha-(5-Methylaminopentyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha-(5-Methylaminopentyl)-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln
US6953774B2 (en) * 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation

Also Published As

Publication number Publication date
WO2002083241A1 (en) 2002-10-24
MXPA03009447A (es) 2004-05-24
NO20034246L (no) 2003-12-15
DE60229047D1 (de) 2008-11-06
HUP0304003A2 (hu) 2004-04-28
US20040171660A1 (en) 2004-09-02
SI1383578T1 (sl) 2008-12-31
ES2311599T3 (es) 2009-02-16
CN1551789A (zh) 2004-12-01
IL158396A0 (en) 2004-05-12
SK14242003A3 (sk) 2004-03-02
BG108323A (bg) 2004-12-30
NO20034246D0 (no) 2003-09-23
CA2444980C (en) 2010-08-17
US8008333B2 (en) 2011-08-30
PL366744A1 (en) 2005-02-07
ATE409066T1 (de) 2008-10-15
EA011310B1 (ru) 2009-02-27
JP2004529924A (ja) 2004-09-30
BR0208920A (pt) 2004-04-20
YU81203A (sh) 2006-05-25
KR20040025916A (ko) 2004-03-26
NZ552873A (en) 2008-05-30
EE200300505A (et) 2004-02-16
HRP20030839A2 (en) 2005-08-31
EP1383578A1 (en) 2004-01-28
EP1383578B1 (en) 2008-09-24
PT1383578E (pt) 2008-10-08
CZ20033107A3 (en) 2004-03-17
UA82648C2 (uk) 2008-05-12
EA200301128A1 (ru) 2004-04-29
AU2002249043B2 (en) 2008-01-10
ZA200307516B (en) 2004-09-27
CA2444980A1 (en) 2002-10-24
AR034036A1 (es) 2004-01-21
CY1108648T1 (el) 2014-04-09

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