BR0208920A - Inibidor de aromatase em dose única para tratamento de infertilidade - Google Patents

Inibidor de aromatase em dose única para tratamento de infertilidade

Info

Publication number
BR0208920A
BR0208920A BR0208920-3A BR0208920A BR0208920A BR 0208920 A BR0208920 A BR 0208920A BR 0208920 A BR0208920 A BR 0208920A BR 0208920 A BR0208920 A BR 0208920A
Authority
BR
Brazil
Prior art keywords
aromatase inhibitor
single dose
infertility
medicament
fsh
Prior art date
Application number
BR0208920-3A
Other languages
English (en)
Inventor
Robert F Casper
Mohamed F M Mitwally
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of BR0208920A publication Critical patent/BR0208920A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"INIBIDOR DE AROMATASE EM DOSE úNICA PARA TRATAMENTO DE INFERTILIDADE". Uso de um inibidor de aromatase (Ais) na preparação de um medicamento para ser usado para induzir a ovulação em fêmeas sofrendo de infertilidade anovulatória que compreende administrar às referidas fêmeas uma dose única de pelo menos um inibidor de aromatase. Uso de um inibidor de aromatase (AI) na preparação de um medicamento compreendendo uma dose única de pelo menos um inibidor de aromatase (AI) para ser administrado a uma fêmea ovulatória sofrendo de infertilidade inexplicada ou outros tipos de infertilidade ovulatória no início de um ou mais ciclos menstruais. Tal medicamento também pode ser administrado a uma fêmea anovulatória em combinação com uma pluralidade de doses diárias de hormónio foliculoestimulante (FSH), pelo que os níveis de dosagem do FSH podem ser reduzidos. Também está descrito o uso de um Al na preparação de um medicamento para ser administrado a uma fêmea que seja pouco sensível a FSH, que compreende uma combinação de uma dose única de Al com uma pluralidade de doses diárias de FSH. Também estão descritas preparações e embalagens farmacêuticas relacionadas.
BR0208920-3A 2001-04-17 2002-04-17 Inibidor de aromatase em dose única para tratamento de infertilidade BR0208920A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28428201P 2001-04-17 2001-04-17
PCT/CA2002/000527 WO2002083241A1 (en) 2001-04-17 2002-04-17 Single dose aromatase inhibitor for treating infertility

Publications (1)

Publication Number Publication Date
BR0208920A true BR0208920A (pt) 2004-04-20

Family

ID=23089583

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208920-3A BR0208920A (pt) 2001-04-17 2002-04-17 Inibidor de aromatase em dose única para tratamento de infertilidade

Country Status (32)

Country Link
US (1) US8008333B2 (pt)
EP (1) EP1383578B1 (pt)
JP (1) JP2004529924A (pt)
KR (1) KR20040025916A (pt)
CN (1) CN1551789A (pt)
AR (1) AR034036A1 (pt)
AT (1) ATE409066T1 (pt)
AU (1) AU2002249043B2 (pt)
BG (1) BG108323A (pt)
BR (1) BR0208920A (pt)
CA (1) CA2444980C (pt)
CY (1) CY1108648T1 (pt)
CZ (1) CZ20033107A3 (pt)
DE (1) DE60229047D1 (pt)
DK (1) DK1383578T3 (pt)
EA (1) EA011310B1 (pt)
EE (1) EE200300505A (pt)
ES (1) ES2311599T3 (pt)
HR (1) HRP20030839A2 (pt)
HU (1) HUP0304003A2 (pt)
IL (1) IL158396A0 (pt)
MX (1) MXPA03009447A (pt)
NO (1) NO20034246L (pt)
NZ (1) NZ552873A (pt)
PL (1) PL366744A1 (pt)
PT (1) PT1383578E (pt)
SI (1) SI1383578T1 (pt)
SK (1) SK14242003A3 (pt)
UA (1) UA82648C2 (pt)
WO (1) WO2002083241A1 (pt)
YU (1) YU81203A (pt)
ZA (1) ZA200307516B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004004634A2 (en) * 2002-07-02 2004-01-15 Pharmacia & Upjohn Company Llc Infertility treatment with exemestane
WO2007000056A1 (en) * 2005-06-28 2007-01-04 Casper Robert F Aromatase inhibitors for emergency contraception
AU2007204969A1 (en) * 2006-01-10 2007-07-19 Cortendo Invest Ab Methods and compositions for treating prostate cancer
US9144569B2 (en) 2010-05-20 2015-09-29 University Of Saskatchewan Methods of administering an aromatase inhibitor, prostaglandin and GnRH for regulating ovulation in cattle
US10004723B2 (en) 2013-04-19 2018-06-26 University Of Saskatchewan Aromatase inhibitor-releasing intravaginal device
US20160022644A1 (en) * 2014-07-22 2016-01-28 Tsu-I Catherine Wang Oral Transmucosal Compositions Including Aromatase Inhibitors for Treating Female Infertility

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728645A (en) * 1982-12-21 1988-03-01 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
US4845227A (en) * 1984-06-18 1989-07-04 Eli Lilly And Company Aromatase inhibitors from azoles
US4602025A (en) * 1984-06-18 1986-07-22 Eli Lilly And Company Aromatase inhibitors
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
GB8726505D0 (en) * 1987-11-12 1987-12-16 Ici Plc Naphtho(2 1-b)furan derivatives
DE4330237C2 (de) 1993-09-02 1995-11-30 Schering Ag 1-Methylsubstituierte Androsta-1,4-dien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
EP0906115A1 (en) * 1996-04-30 1999-04-07 Takeda Chemical Industries, Ltd. COMBINED USE OF GnRH AGONIST AND ANTAGONIST
DE19622457A1 (de) 1996-05-24 1997-11-27 Schering Ag 7alpha-(5-Methylaminopentyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha-(5-Methylaminopentyl)-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln
US6953774B2 (en) * 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation

Also Published As

Publication number Publication date
UA82648C2 (uk) 2008-05-12
YU81203A (sh) 2006-05-25
ES2311599T3 (es) 2009-02-16
KR20040025916A (ko) 2004-03-26
US20040171660A1 (en) 2004-09-02
ZA200307516B (en) 2004-09-27
EE200300505A (et) 2004-02-16
NO20034246D0 (no) 2003-09-23
US8008333B2 (en) 2011-08-30
NZ552873A (en) 2008-05-30
EP1383578A1 (en) 2004-01-28
ATE409066T1 (de) 2008-10-15
CA2444980A1 (en) 2002-10-24
AR034036A1 (es) 2004-01-21
PL366744A1 (en) 2005-02-07
IL158396A0 (en) 2004-05-12
AU2002249043B2 (en) 2008-01-10
EP1383578B1 (en) 2008-09-24
HUP0304003A2 (hu) 2004-04-28
JP2004529924A (ja) 2004-09-30
DE60229047D1 (de) 2008-11-06
SK14242003A3 (sk) 2004-03-02
HRP20030839A2 (en) 2005-08-31
WO2002083241A1 (en) 2002-10-24
EA011310B1 (ru) 2009-02-27
CY1108648T1 (el) 2014-04-09
CZ20033107A3 (en) 2004-03-17
SI1383578T1 (sl) 2008-12-31
DK1383578T3 (da) 2008-11-03
BG108323A (bg) 2004-12-30
CN1551789A (zh) 2004-12-01
PT1383578E (pt) 2008-10-08
CA2444980C (en) 2010-08-17
EA200301128A1 (ru) 2004-04-29
NO20034246L (no) 2003-12-15
MXPA03009447A (es) 2004-05-24

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 8A E 9A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.

B15K Others concerning applications: alteration of classification

Ipc: A61K 31/56 (2006.01), A61P 15/00 (2006.01), A61P 5