HUP0304003A2 - Aromatáz inhibitor alkalmazása meddőség kezelésére alkalmas gyógyszerkészítmény előállítására - Google Patents

Info

Publication number

HUP0304003A2

HUP0304003A2 HU0304003A HUP0304003A HUP0304003A2 HU P0304003 A2 HUP0304003 A2 HU P0304003A2 HU 0304003 A HU0304003 A HU 0304003A HU P0304003 A HUP0304003 A HU P0304003A HU P0304003 A2 HUP0304003 A2 HU P0304003A2

Authority

HU

Hungary

Prior art keywords

group

aromatase inhibitor

administered

single dose

pharmaceutical composition

Prior art date

2001-04-17

Links

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• 239000003886 aromatase inhibitor Substances 0.000 title claims description 99
• 229940122815 Aromatase inhibitor Drugs 0.000 title claims description 70
• 238000011282 treatment Methods 0.000 title claims description 41
• 208000000509 infertility Diseases 0.000 title claims description 22
• 230000036512 infertility Effects 0.000 title claims description 22
• 231100000535 infertility Toxicity 0.000 title claims description 22
• 238000004519 manufacturing process Methods 0.000 title description 6
• 229940126601 medicinal product Drugs 0.000 title 1
• 230000016087 ovulation Effects 0.000 claims description 47
• 108010079345 Follicle Stimulating Hormone Proteins 0.000 claims description 40
• 102000012673 Follicle Stimulating Hormone Human genes 0.000 claims description 40
• 229940028334 follicle stimulating hormone Drugs 0.000 claims description 40
• HPJKCIUCZWXJDR-UHFFFAOYSA-N letrozole Chemical group C1=CC(C#N)=CC=C1C(N1N=CN=C1)C1=CC=C(C#N)C=C1 HPJKCIUCZWXJDR-UHFFFAOYSA-N 0.000 claims description 39
• 229960003881 letrozole Drugs 0.000 claims description 37
• 229940011871 estrogen Drugs 0.000 claims description 28
• 239000000262 estrogen Substances 0.000 claims description 28
• 239000008194 pharmaceutical composition Substances 0.000 claims description 24
• 238000000034 method Methods 0.000 claims description 16
• 230000000624 ovulatory effect Effects 0.000 claims description 14
• 230000027758 ovulation cycle Effects 0.000 claims description 13
• 230000003637 steroidlike Effects 0.000 claims description 11
• YBBLVLTVTVSKRW-UHFFFAOYSA-N anastrozole Chemical compound N#CC(C)(C)C1=CC(C(C)(C#N)C)=CC(CN2N=CN=C2)=C1 YBBLVLTVTVSKRW-UHFFFAOYSA-N 0.000 claims description 10
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• BFYIZQONLCFLEV-DAELLWKTSA-N Aromasine Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=C)C2=C1 BFYIZQONLCFLEV-DAELLWKTSA-N 0.000 claims description 8
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• 125000001425 triazolyl group Chemical group 0.000 description 6
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