CY1108294T1 - Πρωτεϊνες καρκινικων δεικτων και οι χρησεις τους - Google Patents
Πρωτεϊνες καρκινικων δεικτων και οι χρησεις τουςInfo
- Publication number
- CY1108294T1 CY1108294T1 CY20081100911T CY081100911T CY1108294T1 CY 1108294 T1 CY1108294 T1 CY 1108294T1 CY 20081100911 T CY20081100911 T CY 20081100911T CY 081100911 T CY081100911 T CY 081100911T CY 1108294 T1 CY1108294 T1 CY 1108294T1
- Authority
- CY
- Cyprus
- Prior art keywords
- cancer
- tumour
- fluids
- marker proteins
- preparation
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57473—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Η εφεύρεση αναφέρεται στις πρωτεΐνες των καρκινικών δεικτών και στην παρασκευή τους από υγρά ενός ή περισσότερων ασθενών με καρκίνο, όπου τα υγρά που αναφέρθηκαν είναι εκείνα τα οποία συλλέγονται σε μια σωματική κοιλότητα ή χώρο, ο οποίος υπάρχει φυσιολογικά ή είναι αποτέλεσμα της ύπαρξης καρκίνου ή κάποιας ιατρικής παρέμβασης στον καρκίνο. Η εφεύρεση αναφέρεται επίσης στην παρασκευή πρωτεϊνών καρκινικών δεικτών από τις εκκρίσεις των ασθενών με καρκίνο. Οι πρωτεΐνες των καρκινικών δεικτών μπορούν να χρησιμοποιηθούν ως αντιδραστήρια ανοσολογικών προσδιορισμών αναφορικά με την ανίχνευση των δεικτών των αυτοαντισωμάτων που σχετίζονται με την ύπαρξη καρκίνου.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0226622A GB2395270B (en) | 2002-11-14 | 2002-11-14 | Tumour marker proteins and uses thereof |
EP03773863A EP1563307B1 (en) | 2002-11-14 | 2003-11-13 | Tumour marker proteins and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108294T1 true CY1108294T1 (el) | 2014-02-12 |
Family
ID=9947849
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20081100911T CY1108294T1 (el) | 2002-11-14 | 2008-08-25 | Πρωτεϊνες καρκινικων δεικτων και οι χρησεις τους |
Country Status (14)
Country | Link |
---|---|
US (2) | US8592169B2 (el) |
EP (2) | EP1967856A3 (el) |
JP (1) | JP4759267B2 (el) |
AT (1) | ATE397217T1 (el) |
AU (1) | AU2003282245B2 (el) |
CA (1) | CA2545930C (el) |
CY (1) | CY1108294T1 (el) |
DE (1) | DE60321375D1 (el) |
DK (1) | DK1563307T3 (el) |
ES (1) | ES2305530T3 (el) |
GB (3) | GB2424070B (el) |
PT (1) | PT1563307E (el) |
SI (1) | SI1563307T1 (el) |
WO (1) | WO2004044590A1 (el) |
Families Citing this family (28)
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GB9810040D0 (en) | 1998-05-11 | 1998-07-08 | Univ Nottingham | Blood borne tumour markers |
GB9827228D0 (en) * | 1998-12-10 | 1999-02-03 | Univ Nottingham | Cancer detection method and reagents |
US20030232399A1 (en) * | 2000-06-14 | 2003-12-18 | Robertson John Forsyth Russell | Cancer detection methods and reagents |
GB2424070B (en) | 2002-11-14 | 2007-06-27 | Univ Nottingham | Methods for preparing tumour marker proteins |
US7858323B2 (en) | 2004-06-09 | 2010-12-28 | The Regents Of The University Of Michigan | Phage microarray profiling of the humoral response to disease |
JP2006242869A (ja) * | 2005-03-04 | 2006-09-14 | Kyushu Univ | 腫瘍マーカーとしての抗nasp抗体及び抗tmf抗体 |
RU2636532C2 (ru) | 2005-05-27 | 2017-11-23 | Онкиммьюн Лимитед | Улучшенные способы иммуноанализа |
GB2426581A (en) | 2005-05-27 | 2006-11-29 | Univ Nottingham | Immunoassay methods |
WO2006132587A1 (en) * | 2005-06-10 | 2006-12-14 | Forskarpatent I Syd Ab | Tumour marker in brca2 associated breast cancer |
JP5211315B2 (ja) * | 2006-07-25 | 2013-06-12 | 国立大学法人愛媛大学 | 腫瘍マーカ、腫瘍診断キットおよび腫瘍マーカの測定方法 |
GB2441824A (en) * | 2006-09-13 | 2008-03-19 | Oncimmune Ltd | Immunoassay method |
US8574848B2 (en) | 2006-09-13 | 2013-11-05 | Oncimmune Ltd. | Immunoassay methods |
CA2663154C (en) * | 2006-09-13 | 2016-02-23 | Oncimmune Ltd | Improved immunoassay methods |
JP2010519529A (ja) * | 2007-02-23 | 2010-06-03 | プレディクティブ バイオサイエンシーズ コーポレイション | 臨床的介入を指向する診断方法 |
JP2010523990A (ja) * | 2007-04-12 | 2010-07-15 | プロテオシス アクチエンゲゼルシャフト | アネキシンa3による前立腺癌の自己免疫制御 |
GB0725239D0 (en) * | 2007-12-24 | 2008-02-06 | Oncimmune Ltd | Calibrator for autoantibody assay |
AU2010204741B2 (en) * | 2009-01-14 | 2016-01-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Ratio based biomarkers and methods of use thereof |
WO2011116209A2 (en) | 2010-03-17 | 2011-09-22 | The Regents Of The University Of Michigan | Using phage epitopes to profile the immune response |
PT2552959T (pt) | 2010-03-26 | 2017-04-21 | Memorial Sloan Kettering Cancer Center | Anticorpos para muc16 e métodos de utilização dos mesmos |
US20130040839A1 (en) * | 2011-06-27 | 2013-02-14 | Ambergen, Inc. | Method for Diagnosing or Determining the Prognosis of Colorectal Cancer (CRC) Using Novel Autoantigens: Gene Expression Guided Autoantigen Discovery |
TW201312117A (zh) * | 2011-07-28 | 2013-03-16 | Univ Pennsylvania | 用以診斷與漿液相關之腫瘤細胞的症狀及特性的方法及試劑 |
AU2015311679A1 (en) * | 2014-09-04 | 2017-03-23 | Provista Diagnostics, Inc. | Biomarkers for detection of breast cancer |
EP3271398B1 (en) | 2015-03-17 | 2022-08-31 | Memorial Sloan Kettering Cancer Center | Anti-muc16 antibodies and uses thereof |
EP3502701A3 (en) * | 2015-12-11 | 2019-07-10 | Sanford Health | Reagents and methods for monitoring breast cancer therapy |
WO2022013321A2 (en) | 2020-07-14 | 2022-01-20 | Oncimmune Limited | Antibody assay |
GB2600701A (en) | 2020-11-04 | 2022-05-11 | Oncimmune Ltd | Antibody assay |
CN113721021B (zh) * | 2021-09-16 | 2023-07-07 | 郑州大学 | Prkcz自身抗体在食管鳞癌辅助诊断中的应用 |
GB2622246A (en) | 2022-09-08 | 2024-03-13 | Oncimmune Germany Gmbh | Antibody assay |
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2002
- 2002-11-14 GB GB0604694A patent/GB2424070B/en not_active Expired - Fee Related
- 2002-11-14 GB GB0226622A patent/GB2395270B/en not_active Expired - Fee Related
- 2002-11-14 GB GB0604693A patent/GB2424273B/en not_active Expired - Fee Related
-
2003
- 2003-11-13 ES ES03773863T patent/ES2305530T3/es not_active Expired - Lifetime
- 2003-11-13 US US10/534,773 patent/US8592169B2/en not_active Expired - Lifetime
- 2003-11-13 EP EP08007680A patent/EP1967856A3/en not_active Withdrawn
- 2003-11-13 AU AU2003282245A patent/AU2003282245B2/en not_active Ceased
- 2003-11-13 DE DE60321375T patent/DE60321375D1/de not_active Expired - Lifetime
- 2003-11-13 EP EP03773863A patent/EP1563307B1/en not_active Expired - Lifetime
- 2003-11-13 PT PT03773863T patent/PT1563307E/pt unknown
- 2003-11-13 WO PCT/GB2003/004950 patent/WO2004044590A1/en active IP Right Grant
- 2003-11-13 DK DK03773863T patent/DK1563307T3/da active
- 2003-11-13 SI SI200331307T patent/SI1563307T1/sl unknown
- 2003-11-13 JP JP2004550841A patent/JP4759267B2/ja not_active Expired - Fee Related
- 2003-11-13 AT AT03773863T patent/ATE397217T1/de active
- 2003-11-13 CA CA2545930A patent/CA2545930C/en not_active Expired - Fee Related
-
2008
- 2008-08-25 CY CY20081100911T patent/CY1108294T1/el unknown
-
2013
- 2013-11-19 US US14/083,874 patent/US20140080736A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2545930C (en) | 2016-07-12 |
AU2003282245B2 (en) | 2010-05-20 |
GB2395270B (en) | 2006-08-16 |
CA2545930A1 (en) | 2004-05-27 |
DE60321375D1 (de) | 2008-07-10 |
GB0604694D0 (en) | 2006-04-19 |
US8592169B2 (en) | 2013-11-26 |
GB2424070B (en) | 2007-06-27 |
EP1967856A2 (en) | 2008-09-10 |
ATE397217T1 (de) | 2008-06-15 |
EP1967856A3 (en) | 2009-04-15 |
GB2424273B (en) | 2007-06-27 |
US20140080736A1 (en) | 2014-03-20 |
DK1563307T3 (da) | 2008-09-29 |
US20060094069A1 (en) | 2006-05-04 |
AU2003282245A1 (en) | 2004-06-03 |
ES2305530T3 (es) | 2008-11-01 |
GB0226622D0 (en) | 2002-12-24 |
EP1563307B1 (en) | 2008-05-28 |
JP4759267B2 (ja) | 2011-08-31 |
EP1563307A1 (en) | 2005-08-17 |
GB2395270A (en) | 2004-05-19 |
PT1563307E (pt) | 2008-07-16 |
JP2006506612A (ja) | 2006-02-23 |
GB2424070A (en) | 2006-09-13 |
SI1563307T1 (sl) | 2008-10-31 |
GB0604693D0 (en) | 2006-04-19 |
GB2424273A (en) | 2006-09-20 |
WO2004044590A1 (en) | 2004-05-27 |
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