ATE555385T1 - N1,n12-diacetylspermin als tumormarker - Google Patents
N1,n12-diacetylspermin als tumormarkerInfo
- Publication number
- ATE555385T1 ATE555385T1 AT04719642T AT04719642T ATE555385T1 AT E555385 T1 ATE555385 T1 AT E555385T1 AT 04719642 T AT04719642 T AT 04719642T AT 04719642 T AT04719642 T AT 04719642T AT E555385 T1 ATE555385 T1 AT E555385T1
- Authority
- AT
- Austria
- Prior art keywords
- diacetylspermine
- tumor marker
- tumor
- evaluating
- state
- Prior art date
Links
- 239000000439 tumor marker Substances 0.000 title abstract 2
- NPDTUDWGJMBVEP-UHFFFAOYSA-N N(1),N(12)-diacetylspermine Chemical compound CC(=O)NCCCNCCCCNCCCNC(C)=O NPDTUDWGJMBVEP-UHFFFAOYSA-N 0.000 title 1
- NQNXERHVLXYXRO-UHFFFAOYSA-N Diacetylspermine Chemical compound Cl.Cl.CC(=O)NCCCNCCCCNCCCNC(C)=O NQNXERHVLXYXRO-UHFFFAOYSA-N 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003065562 | 2003-03-11 | ||
| JP2003367568 | 2003-10-28 | ||
| PCT/JP2004/003211 WO2004081569A1 (ja) | 2003-03-11 | 2004-03-11 | 腫瘍マーカーとしてのn1,n12-ジアセチルスペルミン |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE555385T1 true ATE555385T1 (de) | 2012-05-15 |
Family
ID=32992951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04719642T ATE555385T1 (de) | 2003-03-11 | 2004-03-11 | N1,n12-diacetylspermin als tumormarker |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20070161059A1 (de) |
| EP (1) | EP1610127B1 (de) |
| JP (2) | JP4608432B2 (de) |
| AT (1) | ATE555385T1 (de) |
| WO (1) | WO2004081569A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7687231B2 (en) * | 2006-01-30 | 2010-03-30 | Yamasa Corporation | Method for determining degree of negative effect of macrophages on vertebrate |
| JP4678785B2 (ja) * | 2006-01-30 | 2011-04-27 | ヤマサ醤油株式会社 | 動物へのマクロファージの悪影響の度合いを検出する方法 |
| JP5166259B2 (ja) * | 2006-06-22 | 2013-03-21 | キッコーマン株式会社 | ポリアミンオキシダーゼの安定化方法と基質特異性の改良方法 |
| JP4947725B2 (ja) * | 2008-03-28 | 2012-06-06 | ヤマサ醤油株式会社 | ジアセチルポリアミンの分解防止法 |
| WO2011136343A1 (ja) * | 2010-04-28 | 2011-11-03 | 財団法人東京都医学総合研究所 | がんの検出方法 |
| EP2572193B1 (de) | 2010-05-21 | 2017-11-01 | The Governors Of The University Of Alberta | Verfahren zur prüfung auf darmkrebs und darmpolypen durch messung von metaboliten im urin |
| CN104678003A (zh) * | 2013-11-29 | 2015-06-03 | 沈阳药科大学 | 尿液用于评估肝癌症疾病的生物标记物 |
| CA3029063C (en) * | 2015-06-26 | 2023-09-05 | Biomark Cancer Systems Inc. | Method of detecting lung cancer |
| CN105527434B (zh) * | 2015-12-31 | 2017-12-19 | 辽宁迈迪生物科技有限公司 | 一种用于二乙酰精胺(das)检测的试剂盒 |
| CN108226483B (zh) * | 2018-01-19 | 2020-06-26 | 辽宁迈迪生物科技股份有限公司 | 一种das检测试剂盒及其制备方法和应用 |
| CN109651503A (zh) * | 2018-11-28 | 2019-04-19 | 天津国际生物医药联合研究院 | 一种人工抗原的制备方法及应用 |
| US11840720B2 (en) | 2019-12-23 | 2023-12-12 | Metabolomic Technologies Inc. | Urinary metabolomic biomarkers for detecting colorectal cancer and polyps |
| EP4222287A4 (de) * | 2020-10-02 | 2024-12-18 | Board of Regents, The University of Texas System | Verfahren zum nachweis und zur behandlung von lungenkrebs |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4663831B2 (ja) * | 1997-07-09 | 2011-04-06 | 日本化薬株式会社 | モノクローナル抗体、細胞株及びn1,n12−ジアセチルスペルミンの測定法 |
| US6673914B1 (en) * | 1998-01-22 | 2004-01-06 | John Wayne Cancer Institute | Human tumor-associated gene |
| US6355623B2 (en) * | 1998-09-24 | 2002-03-12 | Hopital-Sainte-Justine | Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage |
-
2004
- 2004-03-11 AT AT04719642T patent/ATE555385T1/de active
- 2004-03-11 JP JP2005503580A patent/JP4608432B2/ja not_active Expired - Lifetime
- 2004-03-11 US US10/548,658 patent/US20070161059A1/en not_active Abandoned
- 2004-03-11 WO PCT/JP2004/003211 patent/WO2004081569A1/ja not_active Ceased
- 2004-03-11 EP EP04719642A patent/EP1610127B1/de not_active Expired - Lifetime
-
2009
- 2009-06-09 US US12/480,983 patent/US9134313B2/en not_active Expired - Fee Related
-
2010
- 2010-08-09 JP JP2010178388A patent/JP5586368B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2004081569A1 (ja) | 2006-06-15 |
| JP4608432B2 (ja) | 2011-01-12 |
| EP1610127A1 (de) | 2005-12-28 |
| WO2004081569A1 (ja) | 2004-09-23 |
| US20070161059A1 (en) | 2007-07-12 |
| EP1610127B1 (de) | 2012-04-25 |
| JP2011027742A (ja) | 2011-02-10 |
| JP5586368B2 (ja) | 2014-09-10 |
| US9134313B2 (en) | 2015-09-15 |
| EP1610127A4 (de) | 2006-06-14 |
| US20090298098A1 (en) | 2009-12-03 |
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