SI1563307T1 - Tumorski markerski proteini in njihove uporabe - Google Patents

Tumorski markerski proteini in njihove uporabe

Info

Publication number
SI1563307T1
SI1563307T1 SI200331307T SI200331307T SI1563307T1 SI 1563307 T1 SI1563307 T1 SI 1563307T1 SI 200331307 T SI200331307 T SI 200331307T SI 200331307 T SI200331307 T SI 200331307T SI 1563307 T1 SI1563307 T1 SI 1563307T1
Authority
SI
Slovenia
Prior art keywords
cancer
marker proteins
tumour
tumour marker
fluids
Prior art date
Application number
SI200331307T
Other languages
English (en)
Inventor
John Forsyth Russell Robertson
Catherine Rosamund Louise Graves
Original Assignee
Oncimmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncimmune Ltd filed Critical Oncimmune Ltd
Publication of SI1563307T1 publication Critical patent/SI1563307T1/sl

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57473Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/24Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SI200331307T 2002-11-14 2003-11-13 Tumorski markerski proteini in njihove uporabe SI1563307T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0226622A GB2395270B (en) 2002-11-14 2002-11-14 Tumour marker proteins and uses thereof
EP03773863A EP1563307B1 (en) 2002-11-14 2003-11-13 Tumour marker proteins and uses thereof
PCT/GB2003/004950 WO2004044590A1 (en) 2002-11-14 2003-11-13 Tumour marker proteins and uses thereof

Publications (1)

Publication Number Publication Date
SI1563307T1 true SI1563307T1 (sl) 2008-10-31

Family

ID=9947849

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200331307T SI1563307T1 (sl) 2002-11-14 2003-11-13 Tumorski markerski proteini in njihove uporabe

Country Status (14)

Country Link
US (2) US8592169B2 (sl)
EP (2) EP1967856A3 (sl)
JP (1) JP4759267B2 (sl)
AT (1) ATE397217T1 (sl)
AU (1) AU2003282245B2 (sl)
CA (1) CA2545930C (sl)
CY (1) CY1108294T1 (sl)
DE (1) DE60321375D1 (sl)
DK (1) DK1563307T3 (sl)
ES (1) ES2305530T3 (sl)
GB (3) GB2424273B (sl)
PT (1) PT1563307E (sl)
SI (1) SI1563307T1 (sl)
WO (1) WO2004044590A1 (sl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810040D0 (en) 1998-05-11 1998-07-08 Univ Nottingham Blood borne tumour markers
GB9827228D0 (en) * 1998-12-10 1999-02-03 Univ Nottingham Cancer detection method and reagents
US20030232399A1 (en) * 2000-06-14 2003-12-18 Robertson John Forsyth Russell Cancer detection methods and reagents
GB2424273B (en) 2002-11-14 2007-06-27 Univ Nottingham Method for preparing tumour marker protein
US7858323B2 (en) 2004-06-09 2010-12-28 The Regents Of The University Of Michigan Phage microarray profiling of the humoral response to disease
JP2006242869A (ja) * 2005-03-04 2006-09-14 Kyushu Univ 腫瘍マーカーとしての抗nasp抗体及び抗tmf抗体
RU2636532C2 (ru) 2005-05-27 2017-11-23 Онкиммьюн Лимитед Улучшенные способы иммуноанализа
GB2426581A (en) 2005-05-27 2006-11-29 Univ Nottingham Immunoassay methods
WO2006132587A1 (en) * 2005-06-10 2006-12-14 Forskarpatent I Syd Ab Tumour marker in brca2 associated breast cancer
JP5211315B2 (ja) * 2006-07-25 2013-06-12 国立大学法人愛媛大学 腫瘍マーカ、腫瘍診断キットおよび腫瘍マーカの測定方法
CN101632020B (zh) 2006-09-13 2013-11-27 昂西免疫有限公司 改进的免疫测定方法
AU2007297310B2 (en) * 2006-09-13 2013-11-07 Oncimmune Limited Improved immunoassay methods
GB2441824A (en) * 2006-09-13 2008-03-19 Oncimmune Ltd Immunoassay method
CA2679205A1 (en) * 2007-02-23 2008-08-28 Predictive Biosciences Corporation Clinical intervention directed diagnostic methods
WO2008125262A1 (en) 2007-04-12 2008-10-23 Proteosys Ag Autoimmune regulation of prostate cancer by annexin a3
GB0725239D0 (en) * 2007-12-24 2008-02-06 Oncimmune Ltd Calibrator for autoantibody assay
NZ628463A (en) * 2009-01-14 2015-12-24 Us Health Ratio based biomarkers and methods for use thereof
EP3450979A3 (en) 2010-03-17 2019-04-24 The Regents of The University of Michigan Using phage epitopes to profile the immune response
CA3188287A1 (en) 2010-03-26 2011-09-29 Memorial Sloan-Kettering Cancer Center Antibodies to muc16 and methods of use thereof
US20130040839A1 (en) * 2011-06-27 2013-02-14 Ambergen, Inc. Method for Diagnosing or Determining the Prognosis of Colorectal Cancer (CRC) Using Novel Autoantigens: Gene Expression Guided Autoantigen Discovery
EP2737317A2 (en) * 2011-07-28 2014-06-04 The Trustees Of The University Of Pennsylvania Methods for diagnosing cancer by characterization of tumor cells associated with pleural or serous fluids
EP3189332A4 (en) * 2014-09-04 2018-03-21 Provista Diagnostics Inc. Biomarkers for detection of breast cancer
MX2017011822A (es) 2015-03-17 2017-12-07 Memorial Sloan Kettering Cancer Center Anticuerpos anti-muc16 y sus usos.
EP3502701A3 (en) * 2015-12-11 2019-07-10 Sanford Health Reagents and methods for monitoring breast cancer therapy
EP4182693A2 (en) 2020-07-14 2023-05-24 Oncimmune Limited Use of antigen combination for detecting autoantibodies in lung cancer
GB2600701A (en) 2020-11-04 2022-05-11 Oncimmune Ltd Antibody assay
CN113721021B (zh) * 2021-09-16 2023-07-07 郑州大学 Prkcz自身抗体在食管鳞癌辅助诊断中的应用
GB2622246A (en) 2022-09-08 2024-03-13 Oncimmune Germany Gmbh Antibody assay

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ211453A (en) 1984-03-22 1989-01-06 Biotechnology Research Enterpr Aryl azides, their preparation and use in the detection, localisation and isolation of polynucleotides
ATE77700T1 (de) 1986-03-10 1992-07-15 Imre Corp Immunkomplextestverfahren.
AU2253688A (en) 1987-07-24 1989-03-01 Xoma Corporation Methods for breast cancer detection
US4937185A (en) 1987-07-31 1990-06-26 The Ohio State University Research Foundation Detection of circulating antibodies to a cancer marker protein
US5241052A (en) * 1988-03-04 1993-08-31 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses
US7282345B1 (en) 1989-08-04 2007-10-16 Schering Ag C-erbB-2 external domain: GP75
EP0498851B1 (en) * 1989-11-03 1996-01-03 MORTON, Donald L. Urinary tumor associated antigen, antigenic subunits uses and methods of detection
US5157020A (en) 1990-05-24 1992-10-20 Research Corporation Tech., Inc. Synthetic senescent cell antigen
DK9091D0 (da) 1991-01-18 1991-01-18 Novo Nordisk As Fremgangsmaade til fremstilling af antistoffer
DE4120412C1 (sl) 1991-06-20 1993-01-07 Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De
US6322989B1 (en) 1991-11-25 2001-11-27 Yoreh Biotechnologies, Ltd. Whole blood/mitogen assay for the early detection of a subject with ovarian or breast cancer and kit
US6280962B1 (en) 1991-11-25 2001-08-28 Yoreh Biotechnologies Ltd. Whole blood/mitogen assay for the early detection of a subject with cancer and kit
PT1024191E (pt) 1991-12-02 2008-12-22 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
US5753522A (en) * 1991-12-06 1998-05-19 Legacy Good Samaritan Hospital And Medical Center Purified protein for identifying a cancer-associated retinopathy autoantibody
WO1993021529A1 (en) 1992-04-14 1993-10-28 Duke University Method of detecting tumors containing complexes of p53 and hsp70
US5801005A (en) 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US5763164A (en) * 1993-04-16 1998-06-09 Northwestern University Immunogenic cancer proteins and peptides and methods of use
US5747268A (en) * 1993-04-22 1998-05-05 Dade International Inc. Tumor marker control
US5744144A (en) * 1993-07-30 1998-04-28 University Of Pittsburgh University Patent Committee Policy And Procedures Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof
US5721105A (en) 1994-02-20 1998-02-24 B.R.A.H.M.S. Diagnostica Gmbh Method for the immunological determination of proteins and kit for carrying out the method
JPH07294530A (ja) 1994-04-20 1995-11-10 Nippon Igaku Rinshiyou Kensa Kenkyusho:Kk 病原体に対する体液中の抗体検出法
CA2148971A1 (en) 1994-05-26 1995-11-27 Izak Bahar Calibrator matrix
WO1996000084A1 (en) 1994-06-24 1996-01-04 Torchilin Vladimir P Use of autoantibodies for tumor therapy and prophylaxis
IL110464A0 (en) 1994-07-26 1994-10-21 Univ Ramot Novel proteins for the diagnosis, imaging, and therapy of human cancer
US5561049A (en) 1994-09-21 1996-10-01 Behringwerke Ag Method for detecting antibodies
US5876728A (en) 1995-02-15 1999-03-02 Howard David Kass Natural composition extracted from plants used in the treatment of cancer
AUPN568095A0 (en) 1995-09-27 1995-10-26 Austin Research Institute, The Anti-Galalpha(1,3)Gal antibody binding peptides
GB9521544D0 (en) 1995-10-20 1995-12-20 Univ Dundee Activation of P53 protein and therapeutic applications thereof
JPH09189702A (ja) 1996-01-09 1997-07-22 Hitachi Chem Co Ltd 抗ムチン抗体の測定法、癌の測定法及び癌診断薬
JP2001517206A (ja) 1996-08-16 2001-10-02 ザ ジョンズ ホプキンズ ユニヴァーシティ スクール オヴ メディシン 免疫優性な共有黒色腫抗原を発現する黒色腫細胞株およびその使用方法
US8021666B2 (en) * 1997-02-18 2011-09-20 Sloan-Kettering Institute For Cancer Research Method and compositions for stimulation of an immune response to CD20 using a xenogeneic CD20 antigen
AU7713498A (en) 1997-06-03 1998-12-21 Amdl, Inc. Immunoassay for the detection of cancer
AU8267398A (en) * 1997-06-26 1999-01-19 Regents Of The University Of Michigan, The Method for identification of tumor antigens with autoantibodies in serum
DE19805815C1 (de) 1998-02-13 1999-11-11 Ansgar W Lohse Diagnostikum zum Erkennen der autoimmunen Hepatitis
JP4083855B2 (ja) 1998-02-16 2008-04-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 肺癌予後検査方法
GB9810040D0 (en) * 1998-05-11 1998-07-08 Univ Nottingham Blood borne tumour markers
AUPP349098A0 (en) 1998-05-13 1998-06-04 South Eastern Sydney Area Health Service A method of monitoring pancreatic tissue viability
GB9821170D0 (en) * 1998-09-30 1998-11-25 Univ Ulster Marker
JP2002529707A (ja) * 1998-11-03 2002-09-10 セル ジェネシス インコーポレイテッド 癌関連抗原およびそれらの同定の方法
ATE447713T1 (de) * 1998-11-05 2009-11-15 Univ Michigan S100-proteine und -autoantikörper als serummarker für krebs
US6387639B1 (en) 1998-11-10 2002-05-14 Sloan-Kettering Institute For Cancer Research Ma family polypeptides and anti-Ma antibodies
GB9827228D0 (en) 1998-12-10 1999-02-03 Univ Nottingham Cancer detection method and reagents
JP2000281255A (ja) * 1999-03-31 2000-10-10 Seiko Epson Corp 記録装置
US7807810B2 (en) 1999-04-08 2010-10-05 The Ohio State University Research Foundation Nucleic acids encoding the major outer membrane protein of the causative agent of human granulocytic ehrlichiosis and peptides encoded thereby
US6645465B2 (en) * 1999-08-06 2003-11-11 Michigan, University Of The Regents Annexin proteins and autoantibodies as serum markers for cancer
US20020064801A1 (en) 1999-12-01 2002-05-30 Ryan Jeffrey R. Novel and practical serological assay for the clinical diagnosis of leishmaniasis
US6667160B2 (en) 2000-03-15 2003-12-23 Kenneth D. Fine Method for diagnosing immunologic food sensitivity
US20030232399A1 (en) 2000-06-14 2003-12-18 Robertson John Forsyth Russell Cancer detection methods and reagents
US20030138860A1 (en) * 2000-06-14 2003-07-24 Robertson John Forsyth Russell Cancer detection methods and reagents
US6379550B1 (en) * 2000-07-24 2002-04-30 Health Research, Inc. Method for detecting PSA and its molecular forms using thiophilic gel
CA2431201A1 (en) 2000-12-13 2002-08-01 Bio-Rad Laboratories, Inc. Standard diluent for multiplex assays
US7745141B2 (en) 2001-06-21 2010-06-29 New York University Mycobacterial proteins as early antigens for serodiagnosis and vaccines
US20030199464A1 (en) * 2002-04-23 2003-10-23 Silviu Itescu Regeneration of endogenous myocardial tissue by induction of neovascularization
US20030049692A1 (en) 2002-09-16 2003-03-13 Norman Latov Detection of anti-glycolipid antibodies by latex agglutination assay
GB2424273B (en) 2002-11-14 2007-06-27 Univ Nottingham Method for preparing tumour marker protein
JP2005352771A (ja) 2004-06-10 2005-12-22 Hitachi Software Eng Co Ltd 発現プロファイルによるパターン認識システム
US20060141547A1 (en) 2004-11-16 2006-06-29 Das Hasi R Novel diagnostic marker, a diagnostic kit and a method for diagnosis of rheumatoid arthritis
GB2426581A (en) 2005-05-27 2006-11-29 Univ Nottingham Immunoassay methods
EP1789435B1 (en) 2005-09-12 2010-02-24 Industry Foundation of Chonnam National University A method for production of mature natural killer cell
TWI304443B (en) 2005-12-30 2008-12-21 Nat Health Research Institutes Alpha-enolase specific antibody and method of use
CN101632020B (zh) 2006-09-13 2013-11-27 昂西免疫有限公司 改进的免疫测定方法
AU2007297310B2 (en) 2006-09-13 2013-11-07 Oncimmune Limited Improved immunoassay methods
GB0725239D0 (en) * 2007-12-24 2008-02-06 Oncimmune Ltd Calibrator for autoantibody assay

Also Published As

Publication number Publication date
GB2395270B (en) 2006-08-16
EP1563307B1 (en) 2008-05-28
PT1563307E (pt) 2008-07-16
US8592169B2 (en) 2013-11-26
US20140080736A1 (en) 2014-03-20
EP1967856A2 (en) 2008-09-10
EP1563307A1 (en) 2005-08-17
AU2003282245B2 (en) 2010-05-20
JP2006506612A (ja) 2006-02-23
DK1563307T3 (da) 2008-09-29
CY1108294T1 (el) 2014-02-12
CA2545930C (en) 2016-07-12
GB2395270A (en) 2004-05-19
DE60321375D1 (de) 2008-07-10
WO2004044590A1 (en) 2004-05-27
US20060094069A1 (en) 2006-05-04
ES2305530T3 (es) 2008-11-01
GB2424070B (en) 2007-06-27
JP4759267B2 (ja) 2011-08-31
EP1967856A3 (en) 2009-04-15
GB2424273B (en) 2007-06-27
GB2424070A (en) 2006-09-13
GB0226622D0 (en) 2002-12-24
GB2424273A (en) 2006-09-20
GB0604694D0 (en) 2006-04-19
ATE397217T1 (de) 2008-06-15
CA2545930A1 (en) 2004-05-27
GB0604693D0 (en) 2006-04-19
AU2003282245A1 (en) 2004-06-03

Similar Documents

Publication Publication Date Title
GB2395270B (en) Tumour marker proteins and uses thereof
DE602006018578D1 (de) Diagnose- und prognoseverfahren von blasenkrebs.
DE69930666D1 (de) Krebsnachweisverfahren und reagenzien
CY1105129T1 (el) Οπτικος αισθητηρας για την επι τοπου μετρηση αναλυομενων ουσιων
PT1078264E (pt) Marcadores de tumores
ATE529161T1 (de) Tumorbehandlungs-identifikationssystem
EP3640341A3 (en) Assays to determine dna methylation and dna methylation markers of cancer
WO2007089911A3 (en) Methods for detection of circulating tumor cells and methods of diagnosis of cancer in a mammalian subject
WO2009019367A3 (fr) Procede de dosage de l'apolipoproteine ai pour le diagnostic in vitro du cancer colorectal
DE60304300D1 (de) Fahrzeugsensor zur Bestimmung von Abstand und Richtung eines Objektes
FI20050501L (fi) Etätunnistinjärjestelmä ja -menetelmä sekä etätunnistimen käyttö
WO2009019369A3 (fr) Procede de dosage de la plastine-i pour le diagnostic in vitro du cancer colorectal
WO2003031942A8 (en) Reagents and methods useful for detecting diseases of the breast
WO2009019366A3 (fr) Procede de dosage de l'aminoacylase 1 pour le diagnostic in vitro du cancer colorectal
WO2005116850A3 (en) Polynucleotides and polypeptides of ovarian cancer
ATE303451T1 (de) Nanopartikeln für optische sensoren
WO2005106039A8 (en) Ibc-1 (invasive breast cancer-1), a putative oncogene amplified in breast cancer
WO2005078126A3 (en) Means for detecting and treating cancer cells resistant to therapeutic agents
WO2005111610A3 (en) Method of assessing the risk of atherosclerosis
ATE394994T1 (de) Vorrichtungen zur sammlung von material aus einem brustmilchkanal
CA3114923A1 (en) Cancer detection utilizing normal tissue adjacent to breast tumors with genetic ancestry-mapping
DE112007003238A5 (de) Prognostische Marker für die Vorhersage des fünfjährigen progressionsfreien Überlebens von Patienten mit kolorektalen Karzinomen basierend auf Expressionsprofilen von biologischen Proben
RU2018105621A (ru) Способ диагностики рака предстательной железы
FR2868433B1 (fr) Procede pour le pronostic et/ou le diagnostic d'un cancer
GB0308270D0 (en) Diagnostic sensor for the accurate evaluation and analysis of bodily fluids