CY1108130T1 - Σταθεροποιηση των δραστικων παραγοντων μεσω τυποποιημενης παρασκευης σε μορφη νανοσυσσωματωματος - Google Patents

Σταθεροποιηση των δραστικων παραγοντων μεσω τυποποιημενης παρασκευης σε μορφη νανοσυσσωματωματος

Info

Publication number
CY1108130T1
CY1108130T1 CY20081100617T CY081100617T CY1108130T1 CY 1108130 T1 CY1108130 T1 CY 1108130T1 CY 20081100617 T CY20081100617 T CY 20081100617T CY 081100617 T CY081100617 T CY 081100617T CY 1108130 T1 CY1108130 T1 CY 1108130T1
Authority
CY
Cyprus
Prior art keywords
agents
subscribe
stabilization
nano
active factors
Prior art date
Application number
CY20081100617T
Other languages
English (en)
Inventor
Elaine Merisko-Liversidge
Linden Wei
Original Assignee
Elan Pharma International Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25492513&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1108130(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Elan Pharma International Limited filed Critical Elan Pharma International Limited
Publication of CY1108130T1 publication Critical patent/CY1108130T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Περιγράφονται μέθοδοι για την σταθεροποίηση δραστικών παραγόντων, ειδικότερα δε φαρμακευτικών παραγόντων. Η μέθοδος περιλαμβάνει τον σχηματισμό δραστικών παραγόντων μέσα σε μία σύνθεση νανοσυσσωματώματος, περιλαμβάνοντας το δραστικό παράγοντα και έναν τουλάχιστον σταθεροποιητή επιφανείας. Ο συστατικός δραστικός παράγων εκδηλώνει χημική σταθερότητα, ακόμη και μετά από έκθεση, για παράδειγμα, σε μία παρατεταμένη χρονική περίοδο φύλαξης, μία αυξημένη θερμοκρασία, φως, ακτινοβολία, ακτινοβολία που προκαλεί φωτόλυση, μη-φυσιολογικό pΗ, ένζυμα ή άλλους καταλύτες, ύδωρ ή άλλα μόρια διαλυτών, οξειδωτικούς παράγοντες ή άλλες ελεύθερες ρίζες, ή κατάψυξη.
CY20081100617T 2001-09-14 2008-06-10 Σταθεροποιηση των δραστικων παραγοντων μεσω τυποποιημενης παρασκευης σε μορφη νανοσυσσωματωματος CY1108130T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/952,032 US20030054042A1 (en) 2001-09-14 2001-09-14 Stabilization of chemical compounds using nanoparticulate formulations
EP02775709A EP1427395B1 (en) 2001-09-14 2002-09-13 Stabilization of active agents by formulation into nanoparticulate form

Publications (1)

Publication Number Publication Date
CY1108130T1 true CY1108130T1 (el) 2014-02-12

Family

ID=25492513

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100617T CY1108130T1 (el) 2001-09-14 2008-06-10 Σταθεροποιηση των δραστικων παραγοντων μεσω τυποποιημενης παρασκευης σε μορφη νανοσυσσωματωματος

Country Status (11)

Country Link
US (4) US20030054042A1 (el)
EP (2) EP1427395B1 (el)
JP (2) JP2005505568A (el)
AT (1) ATE388690T1 (el)
CA (1) CA2460436C (el)
CY (1) CY1108130T1 (el)
DE (1) DE60225571T2 (el)
DK (1) DK1427395T3 (el)
ES (1) ES2303553T3 (el)
PT (1) PT1427395E (el)
WO (1) WO2003024424A1 (el)

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CA2460436A1 (en) 2003-03-27
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US20090175951A1 (en) 2009-07-09
EP1427395A1 (en) 2004-06-16
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JP2010280687A (ja) 2010-12-16
EP1829530A2 (en) 2007-09-05
US20030054042A1 (en) 2003-03-20
DK1427395T3 (da) 2008-06-30
EP1427395B1 (en) 2008-03-12
JP2005505568A (ja) 2005-02-24
ATE388690T1 (de) 2008-03-15
PT1427395E (pt) 2008-05-20
DE60225571T2 (de) 2009-04-23
CA2460436C (en) 2011-05-10
DE60225571D1 (de) 2008-04-24
WO2003024424A1 (en) 2003-03-27

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