CY1107589T1 - Υδροξυλιωση των βητα-δικαρβονυλιων με καταλυτες ζιρκονιου - Google Patents

Υδροξυλιωση των βητα-δικαρβονυλιων με καταλυτες ζιρκονιου

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Publication number
CY1107589T1
CY1107589T1 CY20071100441T CY071100441T CY1107589T1 CY 1107589 T1 CY1107589 T1 CY 1107589T1 CY 20071100441 T CY20071100441 T CY 20071100441T CY 071100441 T CY071100441 T CY 071100441T CY 1107589 T1 CY1107589 T1 CY 1107589T1
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CY
Cyprus
Prior art keywords
hydroxylation
compound
zirconium
dicarbonyls
beta
Prior art date
Application number
CY20071100441T
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English (en)
Inventor
Albert Loren Casalnuovo
Original Assignee
E.I. Du Pont De Nemours And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E.I. Du Pont De Nemours And Company filed Critical E.I. Du Pont De Nemours And Company
Publication of CY1107589T1 publication Critical patent/CY1107589T1/el

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    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/22—Organic complexes
    • B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
    • B01J31/2208—Oxygen, e.g. acetylacetonates
    • B01J31/2226—Anionic ligands, i.e. the overall ligand carries at least one formal negative charge
    • B01J31/2243—At least one oxygen and one nitrogen atom present as complexing atoms in an at least bidentate or bridging ligand
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    • B01J31/2226—Anionic ligands, i.e. the overall ligand carries at least one formal negative charge
    • B01J31/223—At least two oxygen atoms present in one at least bidentate or bridging ligand
    • B01J31/2234—Beta-dicarbonyl ligands, e.g. acetylacetonates
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    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/50—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
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    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
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Abstract

Η παρούσα εφεύρεση αναφέρεται σε μία διεργασία για την παρασκευή μιας ένωσης του Τύπου I η οποία είναι αχειρική, ρακεμική ή εναντιομερικά εμπλουτισμένη στο κέντρο υδροξυλίωσης το οποίο υποδεικνύεται με * η οποία περιλαμβάνει την επαφή μιας ένωσης του Τύπου ΙΙ με ένα οξειδωτικό επιλεγμένο από οξυγόνο, υπεροξείδιο υδρογόνου, υπεροξέα ή αλκυλυπεροξείδια υπό την παρουσία ενός σύμπλοκου ζιρκονίου, όπου τα R1, R2 και R3 είναι όπως ορίζονται στην αποκάλυψη. Αυτή η εφεύρεση επίσης αναφέρεται σε σύμπλoκα ζιρκονίου χρήσιμα σ' αυτήν την διαδικασία τα οποία περιλαμβάνουν ζιρκόνιο και ένα συνδεσμικό του Τύπου III ή το εναντιομερές του όπου τα J, R6 και n είναι όπως ορίζονται στην αποκάλυψη. Αυτή η εφεύρεση περαιτέρω αναφέρεται σε μία ένωση του Τύπου III ή το εναντιομερές της.
CY20071100441T 2001-06-29 2007-03-29 Υδροξυλιωση των βητα-δικαρβονυλιων με καταλυτες ζιρκονιου CY1107589T1 (el)

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US30214801P 2001-06-29 2001-06-29
US33622901P 2001-10-29 2001-10-29
EP02734686A EP1401575B1 (en) 2001-06-29 2002-06-06 Hydroxylation of beta-dicarbonyls with zirconium catalysts

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CN101503358B (zh) * 2009-03-10 2012-01-25 大连理工大学 高乌甲素作为催化剂制备手性α-羟基-β-二羰基化合物的方法
CN106928062B (zh) * 2015-12-31 2020-05-12 江苏扬农化工股份有限公司 一种α-羟基-β-二羰基化合物手性富集的方法
CN109701655B (zh) 2018-06-08 2019-11-19 京博农化科技有限公司 一种s体茚虫威的制备方法
CN109485568B (zh) 2018-06-08 2019-12-13 京博农化科技有限公司 一种高光学茚虫威中间体的制备方法
CN109776338A (zh) * 2019-03-11 2019-05-21 济南大学 Salan配体、金属-Salan配合物及制备手性α-羟基-β-酮酸酯化合物的方法
CN112345663B (zh) * 2020-10-22 2022-10-21 京博农化科技有限公司 一种5-氯-2-甲氧羰基-1-茚酮酯含量的分析方法
CN113121338B (zh) * 2021-03-31 2022-10-28 浙江工业大学 一种α-羟基-β-酮酸酯类化合物的合成方法
CN114082446B (zh) * 2021-11-17 2023-12-22 南开沧州渤海新区绿色化工研究有限公司 用于制备手性α-羟基-β-酮酸酯化合物的手性锆催化剂及其制备方法
CN114249679B (zh) * 2022-01-05 2023-12-01 东北师范大学 一种制备α,α-偕二氟羰基类化合物的方法

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