CY1107534T1 - Αναμειξιμα με νepο διαλυματα αζαλιδων - Google Patents

Αναμειξιμα με νepο διαλυματα αζαλιδων

Info

Publication number
CY1107534T1
CY1107534T1 CY20071100087T CY071100087T CY1107534T1 CY 1107534 T1 CY1107534 T1 CY 1107534T1 CY 20071100087 T CY20071100087 T CY 20071100087T CY 071100087 T CY071100087 T CY 071100087T CY 1107534 T1 CY1107534 T1 CY 1107534T1
Authority
CY
Cyprus
Prior art keywords
azalide
solutions
mixed
macrolide
water
Prior art date
Application number
CY20071100087T
Other languages
English (en)
Inventor
Lowell R Macy
Raymond E Hopponen
Roger A Wilson
James B Williams
Original Assignee
Merial, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/112,690 external-priority patent/US5958888A/en
Application filed by Merial, Inc. filed Critical Merial, Inc.
Publication of CY1107534T1 publication Critical patent/CY1107534T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Αναμείξιμες με νερό φαρμακευτικές συνθέσεις οι οποίες περιέχουν έως περίπου 40% μιας μακρολίδης όπως ένα αζαλιδικό αντιβιοτικό παρασκευάζονται με αντίδραση της μακρολίδης με οξύ σε ένα μη-υδατικό αναμείξιμο με νερό σύστημα οργανικών διαλυτών.
CY20071100087T 1998-07-09 2007-01-25 Αναμειξιμα με νepο διαλυματα αζαλιδων CY1107534T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/112,690 US5958888A (en) 1996-07-02 1998-07-09 Water miscible macrolide solutions
US09/346,905 US6239112B1 (en) 1998-07-09 1999-07-02 Water miscible macrolide solutions
EP99930886A EP1094822B1 (en) 1998-07-09 1999-07-07 Water miscible azalide solutions

Publications (1)

Publication Number Publication Date
CY1107534T1 true CY1107534T1 (el) 2013-03-13

Family

ID=26810240

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100087T CY1107534T1 (el) 1998-07-09 2007-01-25 Αναμειξιμα με νepο διαλυματα αζαλιδων

Country Status (11)

Country Link
US (1) US6239112B1 (el)
EP (1) EP1094822B1 (el)
JP (1) JP4987187B2 (el)
AU (1) AU4732599A (el)
CA (1) CA2336809C (el)
CY (1) CY1107534T1 (el)
DE (1) DE69934892T2 (el)
DK (1) DK1094822T3 (el)
ES (1) ES2281180T3 (el)
PT (1) PT1094822E (el)
WO (1) WO2000002567A1 (el)

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DE60138876D1 (de) * 2000-03-28 2009-07-16 Sandoz Ag Geschmackmaskierte granulierte teilchen
OA12257A (en) * 2000-04-27 2003-11-06 Pfizer Prod Inc the use of azalide antibiotic compositions for treating or preventing a bacterial or protozoal infection in mammals.
KR100431431B1 (ko) * 2001-04-25 2004-05-14 한미약품 주식회사 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물
JP2003040782A (ja) * 2001-05-31 2003-02-13 Pfizer Prod Inc アザリド抗生物質組成物
US6642276B2 (en) * 2001-10-01 2003-11-04 M/S Ind-Swift Limited Controlled release macrolide pharmaceutical formulations
DE60232005D1 (de) 2001-10-18 2009-05-28 Teva Pharma Stabilisierte azithromycin-zusammensetzungen
US20080149521A9 (en) * 2001-10-18 2008-06-26 Michael Pesachovich Methods of stabilizing azithromycin
CN101785861B (zh) * 2001-10-19 2014-08-13 爱德士实验室公司 用于药理活性化合物的可控释放的可注射组合物
US6946137B2 (en) * 2001-10-19 2005-09-20 Idexx Laboratories, Inc. Methods for the controlled delivery of pharmacologically active compounds
US20040037869A1 (en) * 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
US20040151759A1 (en) * 2002-08-16 2004-08-05 Douglas Cleverly Non-animal product containing veterinary formulations
MXPA05010659A (es) 2003-04-04 2005-12-12 Merial Ltd Formulaciones veterinarias antihelminticas topicas.
US7439268B2 (en) * 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
US20050049210A1 (en) * 2003-08-27 2005-03-03 Idexx Laboratories, Inc. Methods for the controlled delivery of pharmacologically active compounds
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US7683162B2 (en) * 2004-08-30 2010-03-23 Taro Pharmaceutical Industries Limited Process of preparing a crystalline azithromycin monohydrate
BRPI0515917A (pt) 2004-09-23 2008-08-12 Schering Plough Ltd controle de parasitas em animais pelo uso de novos derivados de éter de oxima de trifluorometanossulfonanilida
US7282487B2 (en) * 2004-10-28 2007-10-16 Idexx Laboratories Method for treating bacterial infections in horses or pigs with tilmicosin
JP4750126B2 (ja) * 2004-11-19 2011-08-17 シェーリング−プラウ・リミテッド 殺寄生虫薬２−フェニル−３−（１ｈ−ピロール−２−イル）アクリロニトリル誘導体の使用による動物における寄生虫の制御
AR054380A1 (es) * 2005-06-09 2007-06-20 Schering Plough Ltd Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
MX2009006282A (es) * 2006-12-13 2009-06-23 Schering Plough Ltd Profarmacos solubles en agua de florfenicol y sus analogos.
US8044230B2 (en) * 2006-12-13 2011-10-25 Intervet Inc. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
US7550625B2 (en) * 2007-10-19 2009-06-23 Idexx Laboratories Esters of florfenicol
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
EP2321269B1 (en) * 2008-07-30 2018-09-19 Intervet International B.V. Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
AU2010279587A1 (en) 2009-08-05 2012-02-09 E. I. Du Pont De Nemours And Company Mesoionic pesticides
EP2461684A2 (en) 2009-08-05 2012-06-13 E. I. du Pont de Nemours and Company Mesoionic pesticides
MY156670A (en) 2010-05-27 2016-03-15 Du Pont Crystalline form of 4-[5-[3-chloro-5-(trifluoromethly)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl) amino]ethyl]-1-naphthalenecarboxamide
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
MX2013014326A (es) 2011-06-20 2014-01-23 Du Pont Compuestos heterociclicos para tratar infecciones por helmintos.
JP2015502936A (ja) 2011-11-28 2015-01-29 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ スルホンアミド駆虫薬
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
RU2512683C2 (ru) * 2012-06-08 2014-04-10 Общество с ограниченной ответственностью "ВИК-здоровье животных" Антибактериальная инъекционная фармацевтическая композиция
WO2014099837A1 (en) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anthelmintics
CN103462884B (zh) * 2013-08-21 2015-08-19 天津市中升挑战生物科技有限公司 一种加米霉素注射液及其制备方法
WO2021195126A1 (en) 2020-03-24 2021-09-30 Burnet Michael W Anti-infective and anti-viral compounds and compositions

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AU529422B2 (en) * 1978-10-20 1983-06-09 Eli Lilly And Company Stable erythromycin solution
EP0425443A1 (de) * 1989-10-27 1991-05-02 Ciba-Geigy Ag Injizierbares parasitizides Mittel
AU7957994A (en) * 1993-10-01 1995-05-01 Procter & Gamble Company, The Use of azithromycin for the treatment of adult periodontitis and topical compositions for this use
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
GB9413873D0 (en) * 1994-07-09 1994-08-31 Norbrook Lab Ltd Long-acting oxytetracycline composition
CN1123279A (zh) * 1995-06-15 1996-05-29 沈家祥 阿奇霉素水溶性盐、其注射剂型以及它们的用途
US5723447A (en) * 1996-07-02 1998-03-03 Rhone Merieux, Inc. Water miscible erythromycin solutions
US5958888A (en) * 1996-07-02 1999-09-28 Merial, Inc. Water miscible macrolide solutions

Also Published As

Publication number Publication date
WO2000002567A1 (en) 2000-01-20
CA2336809A1 (en) 2000-01-20
US6239112B1 (en) 2001-05-29
DE69934892T2 (de) 2007-06-14
CA2336809C (en) 2009-06-23
EP1094822A1 (en) 2001-05-02
JP2003522108A (ja) 2003-07-22
EP1094822B1 (en) 2007-01-17
JP4987187B2 (ja) 2012-07-25
DE69934892D1 (de) 2007-03-08
PT1094822E (pt) 2007-03-30
EP1094822A4 (en) 2004-03-31
ES2281180T3 (es) 2007-09-16
DK1094822T3 (da) 2007-05-21
AU4732599A (en) 2000-02-01

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