ES552858A1 - Un procedimiento para la preparacion de derivados de eritromicina. - Google Patents

Un procedimiento para la preparacion de derivados de eritromicina.

Info

Publication number
ES552858A1
ES552858A1 ES552858A ES552858A ES552858A1 ES 552858 A1 ES552858 A1 ES 552858A1 ES 552858 A ES552858 A ES 552858A ES 552858 A ES552858 A ES 552858A ES 552858 A1 ES552858 A1 ES 552858A1
Authority
ES
Spain
Prior art keywords
optionally substituted
erythromycin derivatives
derivatives
erythromycin
imino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552858A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858506381A external-priority patent/GB8506381D0/en
Priority claimed from GB858507626A external-priority patent/GB8507626D0/en
Priority claimed from GB868600553A external-priority patent/GB8600553D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES552858A1 publication Critical patent/ES552858A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Los derivados 11-éter de eritromicina y los correspondientes derivados 9-(opcionalmente sustituído)amino, 9-imino y 9-(opcionalmente sustituído)oxima son nuevos compuestos antibacterianamente activos y pueden ser preparados por alquilación del grupo 11-hidroxi bajo condiciones suaves.
ES552858A 1985-03-12 1986-03-10 Un procedimiento para la preparacion de derivados de eritromicina. Expired ES552858A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB858506381A GB8506381D0 (en) 1985-03-12 1985-03-12 Chemical compounds
GB858507626A GB8507626D0 (en) 1985-03-23 1985-03-23 Chemical compounds
GB868600553A GB8600553D0 (en) 1986-01-10 1986-01-10 Chemical compounds

Publications (1)

Publication Number Publication Date
ES552858A1 true ES552858A1 (es) 1987-11-01

Family

ID=27262619

Family Applications (1)

Application Number Title Priority Date Filing Date
ES552858A Expired ES552858A1 (es) 1985-03-12 1986-03-10 Un procedimiento para la preparacion de derivados de eritromicina.

Country Status (13)

Country Link
US (1) US4847242A (es)
EP (1) EP0201166B1 (es)
KR (1) KR870007196A (es)
AU (1) AU5448886A (es)
DE (1) DE3668894D1 (es)
DK (1) DK109886A (es)
ES (1) ES552858A1 (es)
FI (1) FI861006A (es)
GR (1) GR860655B (es)
HU (1) HUT42502A (es)
JO (1) JO1484B1 (es)
NO (1) NO860901L (es)
PT (1) PT82162B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260938B1 (en) * 1986-09-18 1992-12-09 Taisho Pharmaceutical Co. Ltd Erythromycin a derivatives and method for preparing the same
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
GB8729369D0 (en) * 1987-12-16 1988-01-27 Beecham Group Plc Chemical compounds
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5872229A (en) 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
US5929219A (en) 1997-09-10 1999-07-27 Abbott Laboratories 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
AR023264A1 (es) * 1999-04-08 2002-09-04 Hokuriku Pharmaceutical Derivados de eritromicina
US6673774B2 (en) 2001-12-03 2004-01-06 Enanta Pharmaceuticals, Inc. 11-O-substituted macrolides and their descladinose derivatives
US6750204B2 (en) * 2002-06-25 2004-06-15 Enanta Pharmaceuticals, Inc. 11-C-substituted ketolides
US6812216B2 (en) 2002-06-25 2004-11-02 Enanta Pharmaceuticals, Inc. 11-C-substituted derivatives of clarithromycin
WO2005067919A1 (en) * 2003-12-24 2005-07-28 Enanta Pharmaceuticals, Inc. 11-csubsituted erythromycin derivatives
PT2782922T (pt) * 2011-11-25 2018-02-05 The Kitasato Inst Derivados antibacterianos de tilosina e processos para a sua preparação

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653899A (en) 1952-04-14 1953-09-29 Lilly Co Eli Erythromycin, its salts, and method of preparation
US2761859A (en) 1953-01-14 1956-09-04 Abbott Lab Aqueous soluble salts of erythromycin
US2852429A (en) 1953-08-03 1958-09-16 Lilly Co Eli Antibiotic salts and preparation thereof
US2862921A (en) 1953-08-13 1958-12-02 Upjohn Co Erythromycin esters
US2993833A (en) 1958-07-02 1961-07-25 Lilly Co Eli Erythromycin esters
GB1100504A (en) 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
GB1341022A (en) * 1970-04-13 1973-12-19 Lilly Industries Ltd Erythromycylamine compounds
US3681326A (en) 1971-01-11 1972-08-01 Abbott Lab 9-substituted erythromycin a and b oximes
US3869445A (en) 1973-05-03 1975-03-04 Abbott Lab 4{41 -O-sulfonyl erythromycin-9-O-oxime derivatives
US3836519A (en) 1973-05-04 1974-09-17 Abbott Lab Sulfonyl derivatives of erythromycin
US3884904A (en) 1973-06-21 1975-05-20 Abbott Lab 11-Substituted erythromycin B derivatives
US3842069A (en) 1973-06-21 1974-10-15 Abbott Lab 4"-deoxy-4"-oxoerythromycin b derivatives
US3884903A (en) 1973-06-21 1975-05-20 Abbott Lab 4{41 -Deoxy-4{41 -oxoerythromycin B derivatives
DK139522C (da) * 1975-04-07 1979-08-20 Thomae Gmbh Dr K Analogifremgangsmaade til fremstilling af 9-iminoalkylamino-erythromyciner eller syreadditionssalte deraf
AT342770B (de) 1975-04-07 1978-04-25 Thomae Gmbh Dr K Verfahren zur herstellung neuer erythromycinderivate
US4063014A (en) 1975-06-12 1977-12-13 Abbott Laboratories 4"-O-sulfonyl erythromycin-9-O-oxime derivatives
US4150220A (en) 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives
FR2473525A1 (fr) 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
JPS5849396A (ja) 1981-09-07 1983-03-23 Toyo Jozo Co Ltd ４″−デオキシ−１４員環マクロライド抗生物質
JPS5896095A (ja) 1981-11-30 1983-06-07 Taisho Pharmaceut Co Ltd １１−ｏ−アルキルエリスロマイシンａ誘導体
JPS5896097A (ja) 1981-12-01 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンｂ誘導体
US4382086A (en) 1982-03-01 1983-05-03 Pfizer Inc. 9-Dihydro-11,12-ketal derivatives of erythromycin A and epi-erythromycin A
JPS60214796A (ja) 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法

Also Published As

Publication number Publication date
KR870007196A (ko) 1987-08-17
FI861006A (fi) 1986-09-13
US4847242A (en) 1989-07-11
GR860655B (en) 1986-07-11
PT82162A (en) 1986-04-01
FI861006A0 (fi) 1986-03-11
HUT42502A (en) 1987-07-28
AU5448886A (en) 1986-09-18
NO860901L (no) 1986-09-15
DE3668894D1 (en) 1990-03-15
EP0201166A1 (en) 1986-11-12
JO1484B1 (en) 1988-03-10
DK109886A (da) 1986-09-13
EP0201166B1 (en) 1990-02-07
DK109886D0 (da) 1986-03-10
PT82162B (en) 1987-08-06

Similar Documents

Publication Publication Date Title
NL300017I2 (nl) Gesubstitueerde androsta-1,4-dieen-3,17-dionen, alsmede farmaceutische preparaten die dergelijke verbindingen bevatten.
NO161140C (no) Stempel, saerlig for forbrenningsmotor.
NL193420B (nl) Antibiotische verbindingen, preparaten die deze bevatten en gebruik ervan.
NO860226L (no) Fremgangsmaate for fremstilling av 1-substituert-aryl-1,4-dihydro-4-oksonaftyridin-derivater.
AU5502386A (en) N,n;-dialkylguanidino dipeptide derivatives
ES552858A1 (es) Un procedimiento para la preparacion de derivados de eritromicina.
AU541679B2 (en) Ergolinyl -n:,n:-diethylurea derivatives
AU1829983A (en) Heteroaryl substituted aminomethyl benzene derivatives
IT8540117A1 (it) Gruppo guarnizione anulare per tenuta frontale
EP0194833A3 (en) Erythromycin derivatives
NO863558D0 (no) Foring for elektrolysecelle.
FI894139A0 (fi) Antibiotiska sulfonylaminokarbonyl aktiverade b-laktamer.
DK551585D0 (da) Gelformet antibiotikum til topisk anvendelse
ES551410A0 (es) Procedimiento de preparar derivados rodaninicos.
IT8521945A0 (it) 2-piridilcarbossammide particolarmente per uso farmaceutico.
ES554832A0 (es) Procedimiento para preparar derivados alquenicos.
FI860449A (fi) Komposition foer behandling av graesmatta.
ES545018A0 (es) Procedimiento de preparar agentes de fluoracion de compuestos organicos.
IL78506A0 (en) Oxadiazinone derivatives,process for the preparation thereof,miticidal and nematocidal compositions containing the same
FI862897A0 (fi) Nytt antitrombosmedel baserat pao glykosaminoglykaner, dess framstaellningsfoerfarande och farmaceutiska kompositioner.
AU5427686A (en) 6h-dibenzo (b,d) thiopyran derivatives
AU1275983A (en) Indolizino(8,7beta)indole derivatives
NO861237L (no) Sammensatt, trebasert plate.
AU1180276A (en) N, n'diphenyl-guanidine derivatives
NO862887D0 (no) Fremgangsmaate for bekjempelse av mikroorganismer.

Legal Events

Date Code Title Description
MC2A Annulment

Effective date: 20170619