CY1107271T1 - Μεθοδος για αντιβιοτικη επικαλυψη σωματων με συγκοινωνουσες μικροκοιλοτητες, σωματα επικαλυμμενα με τον τροπο αυτο και χρηση αυτων - Google Patents
Μεθοδος για αντιβιοτικη επικαλυψη σωματων με συγκοινωνουσες μικροκοιλοτητες, σωματα επικαλυμμενα με τον τροπο αυτο και χρηση αυτωνInfo
- Publication number
- CY1107271T1 CY1107271T1 CY081100074T CY081100074T CY1107271T1 CY 1107271 T1 CY1107271 T1 CY 1107271T1 CY 081100074 T CY081100074 T CY 081100074T CY 081100074 T CY081100074 T CY 081100074T CY 1107271 T1 CY1107271 T1 CY 1107271T1
- Authority
- CY
- Cyprus
- Prior art keywords
- gentamycin
- dodekylotheiiki
- tetrakis
- pentakis
- coated
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000011248 coating agent Substances 0.000 title 1
- 238000000576 coating method Methods 0.000 title 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 abstract 8
- 229930182566 Gentamicin Natural products 0.000 abstract 8
- NFHFRUOZVGFOOS-UHFFFAOYSA-N palladium;triphenylphosphane Chemical compound [Pd].C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 NFHFRUOZVGFOOS-UHFFFAOYSA-N 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 229960002518 gentamicin Drugs 0.000 abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- LDMOEFOXLIZJOW-UHFFFAOYSA-N 1-dodecanesulfonic acid Chemical compound CCCCCCCCCCCCS(O)(=O)=O LDMOEFOXLIZJOW-UHFFFAOYSA-N 0.000 abstract 1
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 229910000394 calcium triphosphate Inorganic materials 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 238000007598 dipping method Methods 0.000 abstract 1
- 230000008020 evaporation Effects 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 239000012456 homogeneous solution Substances 0.000 abstract 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- RFWLACFDYFIVMC-UHFFFAOYSA-D pentacalcium;[oxido(phosphonatooxy)phosphoryl] phosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O RFWLACFDYFIVMC-UHFFFAOYSA-D 0.000 abstract 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 abstract 1
- 229920000728 polyester Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/249921—Web or sheet containing structurally defined element or component
- Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
- Laminated Bodies (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10142465A DE10142465A1 (de) | 2001-08-31 | 2001-08-31 | Verfahren zur antibiotischen Beschichtung von nichtmetallischen Körpern mit interkonnektierenden Mikrohohlräumen, nichtmetallischer Körper sowie seine Verwendung |
DE10204307 | 2002-02-01 | ||
EP20020018322 EP1287818B1 (de) | 2001-08-31 | 2002-08-14 | Verfahren zur antibiotischen Beschichtung von Körpern mit interkonnektierenden Mikrohohlräumen, so beschichtete Körper sowie deren Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1107271T1 true CY1107271T1 (el) | 2012-11-21 |
Family
ID=26010028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY081100074T CY1107271T1 (el) | 2001-08-31 | 2008-01-18 | Μεθοδος για αντιβιοτικη επικαλυψη σωματων με συγκοινωνουσες μικροκοιλοτητες, σωματα επικαλυμμενα με τον τροπο αυτο και χρηση αυτων |
Country Status (29)
Country | Link |
---|---|
US (1) | US6984410B2 (en, 2012) |
EP (1) | EP1287818B1 (en, 2012) |
JP (1) | JP3740449B2 (en, 2012) |
CN (1) | CN1203903C (en, 2012) |
AU (1) | AU2002300656B2 (en, 2012) |
BG (1) | BG65774B1 (en, 2012) |
BR (1) | BR0203427A (en, 2012) |
CA (1) | CA2396146C (en, 2012) |
CY (1) | CY1107271T1 (en, 2012) |
CZ (1) | CZ301740B6 (en, 2012) |
DE (1) | DE50211246D1 (en, 2012) |
DK (1) | DK1287818T3 (en, 2012) |
EE (1) | EE200200491A (en, 2012) |
ES (1) | ES2295268T3 (en, 2012) |
GE (1) | GEP20043333B (en, 2012) |
HR (1) | HRP20020680B1 (en, 2012) |
HU (1) | HUP0202916A3 (en, 2012) |
IL (1) | IL150999A0 (en, 2012) |
IS (1) | IS6390A (en, 2012) |
MD (1) | MD2633C2 (en, 2012) |
MX (1) | MXPA02008326A (en, 2012) |
NO (1) | NO20024101L (en, 2012) |
NZ (1) | NZ521043A (en, 2012) |
PL (1) | PL206972B1 (en, 2012) |
PT (1) | PT1287818E (en, 2012) |
RU (1) | RU2236261C2 (en, 2012) |
SA (1) | SA02230286B1 (en, 2012) |
SK (1) | SK9852002A3 (en, 2012) |
YU (1) | YU51902A (en, 2012) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10262176B4 (de) * | 2002-06-21 | 2007-10-04 | Heraeus Kulzer Gmbh | Verfahren zur Herstellung von antibiotisch beschichteten porösen Körpern sowie Verwendung |
ITFI20030105A1 (it) * | 2003-04-14 | 2004-10-15 | Italmed Di Galli Giovanna E Pacini Gigliola S N C | Composizione ad uso odontoiatrico per la rigenerazione ossea |
US20070134287A1 (en) * | 2005-12-09 | 2007-06-14 | Biomet Manufacturing Corp | Method for coating biocompatible substrates with antibiotics |
DE102006016598A1 (de) * | 2006-04-06 | 2007-11-15 | Heraeus Kulzer Gmbh | Beschichtete Vaskulärimplantate |
JP5161452B2 (ja) | 2006-10-03 | 2013-03-13 | 日本コヴィディエン株式会社 | 医療用具の製造方法、医療用具の表面に抗生物質を付与する方法および医療用具 |
CN101721750B (zh) * | 2009-12-25 | 2013-08-07 | 安徽医科大学 | 一种抗菌可降解活性纳米复合仿生骨组织修复材料的制备方法 |
DE102010055560B4 (de) | 2010-12-23 | 2017-02-23 | Heraeus Medical Gmbh | Beschichtungsvorrichtung |
DE102012002209A1 (de) * | 2012-02-07 | 2013-08-08 | Carl Freudenberg Kg | Biodegradierbares Vlies für medizinische Zwecke |
JP6720312B2 (ja) | 2016-09-27 | 2020-07-08 | ワッカー ケミー アクチエンゲゼルシャフトWacker Chemie AG | 球状ポリシルセスキオキサン粒子の製造方法 |
WO2018065058A1 (de) | 2016-10-06 | 2018-04-12 | Wacker Chemie Ag | Verfahren zur herstellung sphärischer polysilsesquioxanpartikel |
EP3700339B1 (en) * | 2017-10-24 | 2025-08-20 | University of Cincinnati | Implant coatings and process for manufacturing implant coatings |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA950831A (en) * | 1972-04-25 | 1974-07-09 | Leonard D. Kurtz | Biocidal salts |
FR2272680B1 (en, 2012) * | 1974-05-29 | 1978-07-21 | Hosbon Sa Lab | |
DE2843963A1 (de) * | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
DE2807132C2 (de) * | 1978-02-20 | 1983-11-03 | Battelle-Institut E.V., 6000 Frankfurt | Implantierbares Pharmaka-Depot |
DE3206725A1 (de) | 1981-05-13 | 1982-12-02 | Merck Patent Gmbh, 6100 Darmstadt | Schwer loesliche salze von aminoglykosidantibiotika |
DE3206726A1 (de) | 1982-02-25 | 1983-09-01 | Merck Patent Gmbh, 6100 Darmstadt | Pharmakadepot |
AU683044B2 (en) * | 1992-12-23 | 1997-10-30 | Saitec S.R.L. | Process for preparing controlled release pharmaceutical forms and the forms thus obtained |
DE4314871A1 (de) | 1993-05-05 | 1994-11-10 | Merck Patent Gmbh | Lösungsmittel für ein schwerlösliches Gentamicin-Salz |
DE4404018A1 (de) | 1994-02-09 | 1995-08-10 | Merck Patent Gmbh | Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat |
US5624704A (en) * | 1995-04-24 | 1997-04-29 | Baylor College Of Medicine | Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent |
WO1997038698A1 (en) | 1996-04-18 | 1997-10-23 | University Technology Corporation | Methods for treating middle and inner ear disorders |
US6417293B1 (en) * | 2000-12-04 | 2002-07-09 | Dow Corning Corporation | Thermoplastic silicone elastomers formed from polyester resins |
DE10114245A1 (de) | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
-
2002
- 2002-05-17 IS IS6390A patent/IS6390A/is unknown
- 2002-06-03 MD MDA20020153A patent/MD2633C2/ro not_active IP Right Cessation
- 2002-06-27 BG BG106881A patent/BG65774B1/bg unknown
- 2002-07-02 CZ CZ20022322A patent/CZ301740B6/cs not_active IP Right Cessation
- 2002-07-04 SK SK985-2002A patent/SK9852002A3/sk unknown
- 2002-07-05 YU YUP51902 patent/YU51902A/sh unknown
- 2002-07-29 CA CA 2396146 patent/CA2396146C/en not_active Expired - Fee Related
- 2002-07-31 IL IL15099902A patent/IL150999A0/xx not_active IP Right Cessation
- 2002-08-12 GE GEAP2002004867 patent/GEP20043333B/en unknown
- 2002-08-13 US US10/217,788 patent/US6984410B2/en not_active Expired - Fee Related
- 2002-08-14 EP EP20020018322 patent/EP1287818B1/de not_active Expired - Lifetime
- 2002-08-14 ES ES02018322T patent/ES2295268T3/es not_active Expired - Lifetime
- 2002-08-14 PT PT02018322T patent/PT1287818E/pt unknown
- 2002-08-14 DK DK02018322T patent/DK1287818T3/da active
- 2002-08-14 DE DE50211246T patent/DE50211246D1/de not_active Expired - Lifetime
- 2002-08-19 AU AU2002300656A patent/AU2002300656B2/en not_active Ceased
- 2002-08-20 HR HR20020680A patent/HRP20020680B1/xx not_active IP Right Cessation
- 2002-08-27 MX MXPA02008326A patent/MXPA02008326A/es active IP Right Grant
- 2002-08-27 NZ NZ521043A patent/NZ521043A/en not_active IP Right Cessation
- 2002-08-28 JP JP2002249580A patent/JP3740449B2/ja not_active Expired - Fee Related
- 2002-08-28 NO NO20024101A patent/NO20024101L/no not_active Application Discontinuation
- 2002-08-28 BR BR0203427A patent/BR0203427A/pt not_active IP Right Cessation
- 2002-08-29 PL PL355778A patent/PL206972B1/pl not_active IP Right Cessation
- 2002-08-30 CN CNB02141503XA patent/CN1203903C/zh not_active Expired - Fee Related
- 2002-08-30 EE EEP200200491A patent/EE200200491A/xx unknown
- 2002-08-30 HU HU0202916A patent/HUP0202916A3/hu unknown
- 2002-08-30 RU RU2002123420A patent/RU2236261C2/ru not_active IP Right Cessation
- 2002-09-03 SA SA02230286A patent/SA02230286B1/ar unknown
-
2008
- 2008-01-18 CY CY081100074T patent/CY1107271T1/el unknown
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