CY1106685T1 - Κρυσταλλος παραγωγου πυριμιδινο νουκλεοζιτη - Google Patents
Κρυσταλλος παραγωγου πυριμιδινο νουκλεοζιτηInfo
- Publication number
- CY1106685T1 CY1106685T1 CY20071100860T CY071100860T CY1106685T1 CY 1106685 T1 CY1106685 T1 CY 1106685T1 CY 20071100860 T CY20071100860 T CY 20071100860T CY 071100860 T CY071100860 T CY 071100860T CY 1106685 T1 CY1106685 T1 CY 1106685T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pyrimidine
- nucleosite
- derivative crystal
- crystal
- derivative
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 2
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003833 nucleoside derivatives Chemical class 0.000 abstract 1
- 239000002718 pyrimidine nucleoside Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Η παρούσα εφεύρεση παρέχει κρυσταλλικές μορφές ενός παραγώγου πυριμιδινο νουκλεοζίτη που έχει εξαιρετική δραστικότητα έναντι νεοπλασιών. Κρυσταλλικές μορφές της ένωσης του ακόλουθου τύπου (Ι):
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001033128 | 2001-02-09 | ||
| PCT/JP2002/000986 WO2002064609A1 (fr) | 2001-02-09 | 2002-02-06 | Cristaux de derive de nucleoside de pyrimidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1106685T1 true CY1106685T1 (el) | 2012-05-23 |
Family
ID=18896929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20071100860T CY1106685T1 (el) | 2001-02-09 | 2007-07-02 | Κρυσταλλος παραγωγου πυριμιδινο νουκλεοζιτη |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1364959B1 (el) |
| JP (2) | JP3748536B2 (el) |
| KR (1) | KR100679904B1 (el) |
| CN (1) | CN100408591C (el) |
| AT (1) | ATE361929T1 (el) |
| AU (1) | AU2002230164B2 (el) |
| BR (2) | BR0207102A (el) |
| CA (1) | CA2437994C (el) |
| CY (1) | CY1106685T1 (el) |
| CZ (1) | CZ303241B6 (el) |
| DE (1) | DE60220024T2 (el) |
| DK (1) | DK1364959T3 (el) |
| ES (1) | ES2286237T3 (el) |
| HU (1) | HU229294B1 (el) |
| IL (2) | IL157216A0 (el) |
| MX (1) | MXPA03007123A (el) |
| NZ (1) | NZ527393A (el) |
| PT (1) | PT1364959E (el) |
| RU (1) | RU2256666C2 (el) |
| WO (1) | WO2002064609A1 (el) |
| ZA (1) | ZA200306121B (el) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101232779B (zh) | 1999-09-02 | 2013-03-27 | 揖斐电株式会社 | 印刷布线板 |
| GB0526419D0 (en) * | 2005-12-23 | 2006-02-08 | Cyclacel Ltd | Formulation |
| GB0625283D0 (en) | 2006-12-19 | 2007-01-24 | Cyclacel Ltd | Combination |
| JP5066737B2 (ja) * | 2007-04-06 | 2012-11-07 | 大鵬薬品工業株式会社 | シチジン誘導体を含有する持続静脈内投与用抗腫瘍剤 |
| US8124593B2 (en) | 2007-11-05 | 2012-02-28 | Cyclacel Limited | Methods of treatment using sapacitabine |
| GB0808357D0 (en) * | 2008-05-08 | 2008-06-18 | Cyclacel Ltd | Process |
| CN102088969B (zh) | 2008-06-09 | 2013-06-12 | 西克拉塞尔有限公司 | 沙帕他滨或cndac与dna甲基转移酶抑制剂如地西他滨和普鲁卡因的组合 |
| PL2696878T3 (pl) | 2011-04-14 | 2020-01-31 | Cyclacel Limited | Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowej |
| CN104302178B (zh) | 2012-03-15 | 2018-07-13 | 西建卡尔有限责任公司 | 表皮生长因子受体激酶抑制剂的固体形式 |
| KR102629310B1 (ko) | 2015-03-09 | 2024-01-24 | 더블유.알. 그레이스 앤드 캄파니-콘. | 니코틴아미드 리보사이드의 결정 형태 |
| CA3086535A1 (en) | 2017-12-22 | 2019-06-27 | Elysium Health, Inc. | Crystalline forms of nicotinamide riboside chloride |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI105556B (fi) * | 1991-09-30 | 2000-09-15 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten pyrimidiiniukleosidijohdannaisten valmistamiseksi, joilla on kasvaimen vastaista vaikutusta |
-
2002
- 2002-02-04 JP JP2002026232A patent/JP3748536B2/ja not_active Expired - Lifetime
- 2002-02-06 MX MXPA03007123A patent/MXPA03007123A/es active IP Right Grant
- 2002-02-06 AT AT02711347T patent/ATE361929T1/de active
- 2002-02-06 HU HU0303159A patent/HU229294B1/hu unknown
- 2002-02-06 KR KR1020037010308A patent/KR100679904B1/ko active IP Right Grant
- 2002-02-06 BR BR0207102-9A patent/BR0207102A/pt not_active Application Discontinuation
- 2002-02-06 BR BRPI0207102A patent/BRPI0207102A8/pt unknown
- 2002-02-06 DE DE60220024T patent/DE60220024T2/de not_active Expired - Lifetime
- 2002-02-06 NZ NZ527393A patent/NZ527393A/en not_active IP Right Cessation
- 2002-02-06 EP EP02711347A patent/EP1364959B1/en not_active Expired - Lifetime
- 2002-02-06 RU RU2003124648/04A patent/RU2256666C2/ru active
- 2002-02-06 CN CNB028079337A patent/CN100408591C/zh not_active Expired - Lifetime
- 2002-02-06 IL IL15721602A patent/IL157216A0/xx active IP Right Grant
- 2002-02-06 AU AU2002230164A patent/AU2002230164B2/en not_active Expired
- 2002-02-06 PT PT02711347T patent/PT1364959E/pt unknown
- 2002-02-06 CZ CZ20032111A patent/CZ303241B6/cs not_active IP Right Cessation
- 2002-02-06 ES ES02711347T patent/ES2286237T3/es not_active Expired - Lifetime
- 2002-02-06 DK DK02711347T patent/DK1364959T3/da active
- 2002-02-06 CA CA2437994A patent/CA2437994C/en not_active Expired - Lifetime
- 2002-02-06 WO PCT/JP2002/000986 patent/WO2002064609A1/ja active IP Right Grant
-
2003
- 2003-08-04 IL IL157216A patent/IL157216A/en unknown
- 2003-08-07 ZA ZA2003/06121A patent/ZA200306121B/en unknown
-
2005
- 2005-08-09 JP JP2005230800A patent/JP4356998B2/ja not_active Expired - Lifetime
-
2007
- 2007-07-02 CY CY20071100860T patent/CY1106685T1/el unknown
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