HUP0303159A2 - Pirimidin-nukleozid-származék kristályos formái - Google Patents

Pirimidin-nukleozid-származék kristályos formái

Info

Publication number
HUP0303159A2
HUP0303159A2 HU0303159A HUP0303159A HUP0303159A2 HU P0303159 A2 HUP0303159 A2 HU P0303159A2 HU 0303159 A HU0303159 A HU 0303159A HU P0303159 A HUP0303159 A HU P0303159A HU P0303159 A2 HUP0303159 A2 HU P0303159A2
Authority
HU
Hungary
Prior art keywords
crystalline form
relates
pyrimidine nucleoside
nucleoside derivative
medicinal preparations
Prior art date
Application number
HU0303159A
Other languages
English (en)
Inventor
Susumu Harashima
Eiji Numagami
Keiichi Ohtsuka
Takashi Takita
Original Assignee
Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Company, Limited filed Critical Sankyo Company, Limited
Publication of HUP0303159A2 publication Critical patent/HUP0303159A2/hu
Publication of HUP0303159A3 publication Critical patent/HUP0303159A3/hu
Publication of HU229294B1 publication Critical patent/HU229294B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A találmány az (I) képletű pirimidin-nukleozid-származék kristályosformáira vonatkozik, amelynek kiváló tumor elleni aktivitása van. Atalálmány továbbá gyógyászati készítményekre, előnyösen tumor ellenihatású gyógyászati készítményekre vonatkozik, amelyek hatóanyagként azemlített kristályos formát tartalmazzák. A találmány továbbá azemlített kristályos forma alkalmazására vonatkozik az említettgyógyászati készítmény előállítására. A találmány szerinti gyógyászatikészítményekkel különböző megbetegedések, előnyösen tumorok kezelhetőkmegelőzés vagy gyógyítás céljából, e kezelés során egy, ilyen kezeléstvagy megelőzést igénylő melegvérűnek, előnyösen embernek az említettkristályos forma farmakológiailag hatásos mennyiségben kerül beadásra. Ó
HU0303159A 2001-02-09 2002-02-06 Crystal of pyrimidine nucleoside derivative HU229294B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001033128 2001-02-09
PCT/JP2002/000986 WO2002064609A1 (fr) 2001-02-09 2002-02-06 Cristaux de derive de nucleoside de pyrimidine

Publications (3)

Publication Number Publication Date
HUP0303159A2 true HUP0303159A2 (hu) 2003-12-29
HUP0303159A3 HUP0303159A3 (en) 2007-06-28
HU229294B1 HU229294B1 (en) 2013-10-28

Family

ID=18896929

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303159A HU229294B1 (en) 2001-02-09 2002-02-06 Crystal of pyrimidine nucleoside derivative

Country Status (21)

Country Link
EP (1) EP1364959B1 (hu)
JP (2) JP3748536B2 (hu)
KR (1) KR100679904B1 (hu)
CN (1) CN100408591C (hu)
AT (1) ATE361929T1 (hu)
AU (1) AU2002230164B2 (hu)
BR (2) BR0207102A (hu)
CA (1) CA2437994C (hu)
CY (1) CY1106685T1 (hu)
CZ (1) CZ303241B6 (hu)
DE (1) DE60220024T2 (hu)
DK (1) DK1364959T3 (hu)
ES (1) ES2286237T3 (hu)
HU (1) HU229294B1 (hu)
IL (2) IL157216A0 (hu)
MX (1) MXPA03007123A (hu)
NZ (1) NZ527393A (hu)
PT (1) PT1364959E (hu)
RU (1) RU2256666C2 (hu)
WO (1) WO2002064609A1 (hu)
ZA (1) ZA200306121B (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101232779B (zh) 1999-09-02 2013-03-27 揖斐电株式会社 印刷布线板
GB0526419D0 (en) * 2005-12-23 2006-02-08 Cyclacel Ltd Formulation
GB0625283D0 (en) 2006-12-19 2007-01-24 Cyclacel Ltd Combination
JP5066737B2 (ja) * 2007-04-06 2012-11-07 大鵬薬品工業株式会社 シチジン誘導体を含有する持続静脈内投与用抗腫瘍剤
US8124593B2 (en) 2007-11-05 2012-02-28 Cyclacel Limited Methods of treatment using sapacitabine
GB0808357D0 (en) * 2008-05-08 2008-06-18 Cyclacel Ltd Process
CN102088969B (zh) 2008-06-09 2013-06-12 西克拉塞尔有限公司 沙帕他滨或cndac与dna甲基转移酶抑制剂如地西他滨和普鲁卡因的组合
PL2696878T3 (pl) 2011-04-14 2020-01-31 Cyclacel Limited Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowej
CN104302178B (zh) 2012-03-15 2018-07-13 西建卡尔有限责任公司 表皮生长因子受体激酶抑制剂的固体形式
KR102629310B1 (ko) 2015-03-09 2024-01-24 더블유.알. 그레이스 앤드 캄파니-콘. 니코틴아미드 리보사이드의 결정 형태
CA3086535A1 (en) 2017-12-22 2019-06-27 Elysium Health, Inc. Crystalline forms of nicotinamide riboside chloride

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI105556B (fi) * 1991-09-30 2000-09-15 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten pyrimidiiniukleosidijohdannaisten valmistamiseksi, joilla on kasvaimen vastaista vaikutusta

Also Published As

Publication number Publication date
ZA200306121B (en) 2005-01-26
HU229294B1 (en) 2013-10-28
BR0207102A (pt) 2004-01-27
MXPA03007123A (es) 2003-11-18
HUP0303159A3 (en) 2007-06-28
DE60220024T2 (de) 2007-11-22
JP4356998B2 (ja) 2009-11-04
DK1364959T3 (da) 2007-06-04
RU2256666C2 (ru) 2005-07-20
CZ20032111A3 (cs) 2003-12-17
ES2286237T3 (es) 2007-12-01
CZ303241B6 (cs) 2012-06-13
EP1364959A4 (en) 2004-03-24
CN1501939A (zh) 2004-06-02
EP1364959A1 (en) 2003-11-26
IL157216A (en) 2008-03-20
JP2002308895A (ja) 2002-10-23
BRPI0207102A8 (pt) 2018-02-27
KR100679904B1 (ko) 2007-02-07
AU2002230164B2 (en) 2005-04-07
WO2002064609A1 (fr) 2002-08-22
KR20030081424A (ko) 2003-10-17
JP2006008699A (ja) 2006-01-12
ATE361929T1 (de) 2007-06-15
CA2437994C (en) 2011-05-17
IL157216A0 (en) 2004-02-19
DE60220024D1 (en) 2007-06-21
CN100408591C (zh) 2008-08-06
CY1106685T1 (el) 2012-05-23
CA2437994A1 (en) 2002-08-22
EP1364959B1 (en) 2007-05-09
JP3748536B2 (ja) 2006-02-22
RU2003124648A (ru) 2005-02-27
PT1364959E (pt) 2007-07-23
NZ527393A (en) 2004-07-30

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