CU24326B1 - COMPOSICIÓN FARMACÉUTICA QUE INCLUYE UN INHIBIDOR DE LA HMG-Coa REDUCTASA QUE MINIMIZA LA INTERACCIÓN DEL ÁCIDO ACETILSALICÍLICO CON LA ESTATINA - Google Patents
COMPOSICIÓN FARMACÉUTICA QUE INCLUYE UN INHIBIDOR DE LA HMG-Coa REDUCTASA QUE MINIMIZA LA INTERACCIÓN DEL ÁCIDO ACETILSALICÍLICO CON LA ESTATINAInfo
- Publication number
- CU24326B1 CU24326B1 CUP2015000173A CU20150173A CU24326B1 CU 24326 B1 CU24326 B1 CU 24326B1 CU P2015000173 A CUP2015000173 A CU P2015000173A CU 20150173 A CU20150173 A CU 20150173A CU 24326 B1 CU24326 B1 CU 24326B1
- Authority
- CU
- Cuba
- Prior art keywords
- statin
- hmg
- interaction
- pharmaceutical composition
- inhibitor
- Prior art date
Links
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title abstract 4
- 230000003993 interaction Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 2
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13170909.9A EP2810644A1 (en) | 2013-06-06 | 2013-06-06 | Oral formulation for the treatment of cardiovascular diseases |
| PCT/EP2014/061735 WO2014195421A1 (en) | 2013-06-06 | 2014-06-05 | Oral formulation for the treatment of cardiovascular diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20150173A7 CU20150173A7 (es) | 2016-06-29 |
| CU24326B1 true CU24326B1 (es) | 2018-03-13 |
Family
ID=48569993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2015000173A CU24326B1 (es) | 2013-06-06 | 2014-06-05 | COMPOSICIÓN FARMACÉUTICA QUE INCLUYE UN INHIBIDOR DE LA HMG-Coa REDUCTASA QUE MINIMIZA LA INTERACCIÓN DEL ÁCIDO ACETILSALICÍLICO CON LA ESTATINA |
Country Status (42)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018514523A (ja) * | 2015-04-16 | 2018-06-07 | ノバルティス アーゲー | リボシクリブ錠剤 |
| CN111135149B (zh) * | 2018-11-04 | 2021-05-11 | 张家港市中医医院 | 一种瑞舒伐他汀钙片及其制备方法 |
| CN110693929A (zh) * | 2019-09-09 | 2020-01-17 | 安徽中医药大学 | 复方药物组份在治疗脑梗死恢复期中的应用 |
| HUE066396T2 (hu) | 2022-06-30 | 2024-08-28 | Ferrer Int | Orális kapszulák, amelyek atorvasztatin tablettákat tartalmaznak, amelyek megfelelõ oldódási profilt és biológiai hozzáférhetõséget mutatnak |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4231938A (en) | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
| WO1984002131A1 (fr) | 1982-11-22 | 1984-06-07 | Sandoz Ag | Produits analogues de mevalolactone et leurs derives, leurs procedes de production, compositions pharmaceutiques les contenant ainsi que leur utilisation en tant que produits pharmaceutiques |
| MY119161A (en) | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
| EP0904082A4 (en) | 1996-04-17 | 2001-09-26 | Merck & Co Inc | COMBINATION THERAPY TO REDUCE THE RISKS OF HEART CIRCULAR DISEASES |
| US6235311B1 (en) * | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
| US6376672B1 (en) | 1999-04-27 | 2002-04-23 | Hoffmann-La Roche Inc. | Naphthalenylmethoxypiperidines as renin inhibitors |
| US6197959B1 (en) | 1999-04-27 | 2001-03-06 | Hoffmann-La Roche Inc. | Piperidine derivatives |
| US6448323B1 (en) | 1999-07-09 | 2002-09-10 | Bpsi Holdings, Inc. | Film coatings and film coating compositions based on polyvinyl alcohol |
| PL202884B1 (pl) | 2000-02-10 | 2009-07-31 | Bpsi Holdings | Nietoksyczna, jadalna, powłokotwórcza kompozycja proszkowa zabezpieczająca przed działaniem soku żołądkowego, sposób sporządzania wodnego układu dyspersyjnego oraz sposób powlekania substratów |
| US6576256B2 (en) * | 2001-08-28 | 2003-06-10 | The Brigham And Women's Hospital, Inc. | Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
| US6669955B2 (en) * | 2001-08-28 | 2003-12-30 | Longwood Pharmaceutical Research, Inc. | Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
| US20040115265A1 (en) * | 2002-12-11 | 2004-06-17 | Loutfy Benkerrour | Multilayered tablet containing pravastatin and aspirin and method |
| WO2004080488A2 (de) | 2003-03-10 | 2004-09-23 | Bayer Healthcare Ag | Kombinationspräparate von acetylsalicylsäure mit einem hmg-coa-reduktase |
| WO2005011586A2 (en) | 2003-07-28 | 2005-02-10 | Dr. Reddy's Laboratories, Inc. | Treatment and preventi0n of cardiovascular events |
| WO2005019286A1 (ja) | 2003-08-20 | 2005-03-03 | Shionogi & Co., Ltd. | 新規コーティング組成物 |
| CN1882528A (zh) | 2003-11-26 | 2006-12-20 | 诺瓦提斯公司 | 有机化合物 |
| WO2006000052A1 (en) * | 2004-06-28 | 2006-01-05 | Howard J Smith & Associates Pty Ltd | Composition and method for treatment and prevention of atherosclerosis |
| TW200700358A (en) | 2005-03-11 | 2007-01-01 | Speedel Experimenta Ag | Organic compounds |
| US20070009591A1 (en) | 2005-07-07 | 2007-01-11 | Trivedi Jay S | ACE inhibitor formulation |
| US20070116756A1 (en) | 2005-11-23 | 2007-05-24 | Dr. Reddy's Laboratories Limited | Stable pharmaceutical compositions |
| US7427414B2 (en) | 2006-01-18 | 2008-09-23 | Astron Research Limited | Modified release oral dosage form using co-polymer of polyvinyl acetate |
| CN101176725A (zh) * | 2006-07-14 | 2008-05-14 | 兰贝克赛实验室有限公司 | 辛伐他汀和阿司匹林的稳定剂型 |
| HRP20141008T1 (hr) * | 2007-02-09 | 2015-01-02 | Alphapharm Pty Ltd | Oblik doziranja koji sadrži dva aktivna farmaceutska sastojka u razliäśitim fizikalnim oblicima |
| KR100955669B1 (ko) | 2007-08-13 | 2010-05-06 | 한올바이오파마주식회사 | ＨＭＧＣｏＡ 환원효소 저해제와 아스피린을 포함하는 복합제제 및 그의 제조방법 |
| US20090076062A1 (en) | 2007-09-13 | 2009-03-19 | Juergen Klaus Maibaum | Organic Compounds |
| WO2009118359A2 (en) * | 2008-03-28 | 2009-10-01 | Ferrer Internacional S.A. | Capsule for the prevention of cardiovascular diseases |
| CA2754134C (en) * | 2009-02-11 | 2018-09-18 | Cadila Pharmaceuticals Ltd. | Stable pharmaceutical composition for atherosclerosis |
| AU2010242938A1 (en) * | 2009-04-30 | 2011-11-17 | Dr. Reddy's Laboratories Ltd. | Fixed dose drug combination formulations |
| KR20120130078A (ko) | 2009-11-09 | 2012-11-28 | 메디비르 아베 | 신규한 1,3-옥사졸리딘 화합물 및 이의 레닌 억제제로서의 용도 |
| KR101193493B1 (ko) * | 2010-02-02 | 2012-10-22 | 한미사이언스 주식회사 | 소수성 첨가제가 함유된 분리막으로 코팅된 아스피린 및 ＨＭＧ?ＣｏＡ 환원효소 억제제를 포함하는 복합제제 |
| CN102049049A (zh) * | 2010-11-27 | 2011-05-11 | 王定豪 | 包含阿司匹林盐和他汀类药物的药物组合物 |
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2013
- 2013-06-06 EP EP13170909.9A patent/EP2810644A1/en not_active Withdrawn
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2014
- 2014-05-20 AR ARP140101992A patent/AR096350A1/es not_active Application Discontinuation
- 2014-06-04 TW TW103119340A patent/TWI630928B/zh active
- 2014-06-05 BR BR112015030350-1A patent/BR112015030350B1/pt not_active IP Right Cessation
- 2014-06-05 PL PL14728940T patent/PL2986281T3/pl unknown
- 2014-06-05 AP AP2015008882A patent/AP2015008882A0/xx unknown
- 2014-06-05 NZ NZ714707A patent/NZ714707A/en unknown
- 2014-06-05 JP JP2016517607A patent/JP6151854B2/ja active Active
- 2014-06-05 MA MA38699A patent/MA38699B1/fr unknown
- 2014-06-05 MD MDA20160001A patent/MD4475C1/ro active IP Right Grant
- 2014-06-05 WO PCT/EP2014/061735 patent/WO2014195421A1/en not_active Ceased
- 2014-06-05 ES ES14728940.9T patent/ES2620078T3/es active Active
- 2014-06-05 PT PT147289409T patent/PT2986281T/pt unknown
- 2014-06-05 SI SI201430175A patent/SI2986281T1/sl unknown
- 2014-06-05 TN TN2015000501A patent/TN2015000501A1/en unknown
- 2014-06-05 KR KR1020157033956A patent/KR101839665B1/ko not_active Expired - Fee Related
- 2014-06-05 HU HUE14728940A patent/HUE033458T2/en unknown
- 2014-06-05 AU AU2014276883A patent/AU2014276883B2/en active Active
- 2014-06-05 RS RS20170286A patent/RS55786B1/sr unknown
- 2014-06-05 MY MYPI2015704409A patent/MY181272A/en unknown
- 2014-06-05 SG SG11201509353QA patent/SG11201509353QA/en unknown
- 2014-06-05 EA EA201600012A patent/EA028969B1/ru unknown
- 2014-06-05 MX MX2015015753A patent/MX347801B/es active IP Right Grant
- 2014-06-05 EP EP14728940.9A patent/EP2986281B1/en active Active
- 2014-06-05 GE GEAP201414027A patent/GEP201706743B/en unknown
- 2014-06-05 CU CUP2015000173A patent/CU24326B1/es unknown
- 2014-06-05 DK DK14728940.9T patent/DK2986281T3/en active
- 2014-06-05 CA CA2912350A patent/CA2912350C/en active Active
- 2014-06-05 PE PE2015002519A patent/PE20160051A1/es unknown
- 2014-06-05 US US14/893,902 patent/US10617699B2/en active Active
- 2014-06-05 EP EP16204436.6A patent/EP3175849A1/en not_active Withdrawn
- 2014-06-05 UA UAA201512002A patent/UA113806C2/uk unknown
- 2014-06-06 CN CN202110259129.4A patent/CN113143888A/zh active Pending
- 2014-06-06 CN CN201410249657.1A patent/CN104224804A/zh active Pending
-
2015
- 2015-05-28 HK HK15105100.9A patent/HK1204562A1/xx unknown
- 2015-11-12 IL IL242569A patent/IL242569B/en active IP Right Grant
- 2015-11-16 ZA ZA2015/08452A patent/ZA201508452B/en unknown
- 2015-12-01 EC ECIEPI201550273A patent/ECSP15050273A/es unknown
- 2015-12-03 CR CR20150635A patent/CR20150635A/es unknown
- 2015-12-04 NI NI201500171A patent/NI201500171A/es unknown
- 2015-12-04 CL CL2015003561A patent/CL2015003561A1/es unknown
- 2015-12-04 PH PH12015502706A patent/PH12015502706A1/en unknown
- 2015-12-05 SA SA515370243A patent/SA515370243B1/ar unknown
- 2015-12-08 DO DO2015000296A patent/DOP2015000296A/es unknown
-
2017
- 2017-03-17 CY CY20171100340T patent/CY1118766T1/el unknown
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