CS33291A2 - Method of 7-amino-3-methoxymethylcef-3-em-4-carboxylic acid's preparation - Google Patents

Method of 7-amino-3-methoxymethylcef-3-em-4-carboxylic acid's preparation Download PDF

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Publication number
CS33291A2
CS33291A2 CS91332A CS33291A CS33291A2 CS 33291 A2 CS33291 A2 CS 33291A2 CS 91332 A CS91332 A CS 91332A CS 33291 A CS33291 A CS 33291A CS 33291 A2 CS33291 A2 CS 33291A2
Authority
CS
Czechoslovakia
Prior art keywords
acid
formula
compound
salt
equivalents
Prior art date
Application number
CS91332A
Other languages
Czech (cs)
English (en)
Inventor
Friedhelm Dr Adam
Walter Dr Durckheimer
Rolf Dr Horlein
Burghard Dr Mencke
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CS33291A2 publication Critical patent/CS33291A2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS91332A 1990-02-13 1991-02-11 Method of 7-amino-3-methoxymethylcef-3-em-4-carboxylic acid's preparation CS33291A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4004370A DE4004370A1 (de) 1990-02-13 1990-02-13 Verfahren zur herstellung von 7-amino-3-methoxymethyl-ceph-3-em-4-carbonsaeure

Publications (1)

Publication Number Publication Date
CS33291A2 true CS33291A2 (en) 1991-09-15

Family

ID=6400034

Family Applications (1)

Application Number Title Priority Date Filing Date
CS91332A CS33291A2 (en) 1990-02-13 1991-02-11 Method of 7-amino-3-methoxymethylcef-3-em-4-carboxylic acid's preparation

Country Status (19)

Country Link
EP (1) EP0442385A3 (no)
JP (1) JPH04211088A (no)
KR (1) KR910015584A (no)
CN (1) CN1054984A (no)
AU (1) AU7095691A (no)
CA (1) CA2036208A1 (no)
CS (1) CS33291A2 (no)
DE (1) DE4004370A1 (no)
FI (1) FI910662A (no)
HU (1) HUT59687A (no)
IE (1) IE910464A1 (no)
IL (1) IL97210A0 (no)
MA (1) MA22061A1 (no)
MY (1) MY105374A (no)
NO (1) NO910556L (no)
NZ (1) NZ237063A (no)
PL (1) PL289034A1 (no)
PT (1) PT96729A (no)
ZA (1) ZA911025B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69110107T2 (de) * 1990-11-07 1996-02-01 Sankyo Co Verfahren zur Herstellung von 3-Alkoxymethyl Cephalosporinderivate.
AT401177B (de) * 1993-10-22 1996-07-25 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3-cephem-4-carbonsäure-derivaten
WO2017153824A1 (en) 2016-03-07 2017-09-14 Dhanuka Laboratories Ltd. A process for alkylating the hydroxymethyl group at position -3 of cephalosporins
CN109956958B (zh) * 2019-04-02 2020-06-16 河北合佳医药科技集团股份有限公司 一种7-氨基-3-甲氧基甲基-3-头孢烯-4-羧酸合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT384222B (de) * 1985-06-03 1987-10-12 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren
EP0262744B1 (en) * 1986-10-02 1994-03-23 Asahi Kasei Kogyo Kabushiki Kaisha A process for preparing 3-alkoxymethylcephalosphorins
JP2612493B2 (ja) * 1988-05-24 1997-05-21 旭化成工業株式会社 ３―置換メチル―３―セフェム―４―カルボン酸類の製造方法

Also Published As

Publication number Publication date
IL97210A0 (en) 1992-05-25
FI910662A0 (fi) 1991-02-11
HU910466D0 (en) 1991-08-28
NZ237063A (en) 1992-04-28
JPH04211088A (ja) 1992-08-03
AU7095691A (en) 1991-08-15
DE4004370A1 (de) 1991-08-14
PL289034A1 (en) 1992-03-23
IE910464A1 (en) 1991-08-14
EP0442385A3 (en) 1992-05-13
NO910556D0 (no) 1991-02-12
EP0442385A2 (de) 1991-08-21
ZA911025B (en) 1991-10-30
MY105374A (en) 1994-09-30
MA22061A1 (fr) 1991-10-01
KR910015584A (ko) 1991-09-30
HUT59687A (en) 1992-06-29
CA2036208A1 (en) 1991-08-14
FI910662A (fi) 1991-08-14
CN1054984A (zh) 1991-10-02
NO910556L (no) 1991-08-14
PT96729A (pt) 1991-10-31

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