CS274460B2 - Method of 1-cyclopropyl-7-substituted-6-fluor-4-oxo-1,4-dihydroquinoline-3-carboxylic acid's derivatives production - Google Patents
Method of 1-cyclopropyl-7-substituted-6-fluor-4-oxo-1,4-dihydroquinoline-3-carboxylic acid's derivatives production Download PDFInfo
- Publication number
- CS274460B2 CS274460B2 CS242088A CS242088A CS274460B2 CS 274460 B2 CS274460 B2 CS 274460B2 CS 242088 A CS242088 A CS 242088A CS 242088 A CS242088 A CS 242088A CS 274460 B2 CS274460 B2 CS 274460B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- compound
- salt
- acid
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU871505A HU198709B (en) | 1987-04-08 | 1987-04-08 | Process for producing quinoline-carboxylic acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
CS242088A2 CS242088A2 (en) | 1990-09-12 |
CS274460B2 true CS274460B2 (en) | 1991-04-11 |
Family
ID=10954767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS242088A CS274460B2 (en) | 1987-04-08 | 1988-04-08 | Method of 1-cyclopropyl-7-substituted-6-fluor-4-oxo-1,4-dihydroquinoline-3-carboxylic acid's derivatives production |
Country Status (13)
Country | Link |
---|---|
US (2) | US5091530A (zh) |
EP (1) | EP0309537B1 (zh) |
JP (1) | JP2693987B2 (zh) |
CN (1) | CN1025616C (zh) |
AT (1) | ATE124687T1 (zh) |
AU (1) | AU612648B2 (zh) |
CS (1) | CS274460B2 (zh) |
DD (1) | DD269848A5 (zh) |
DE (1) | DE3854109T2 (zh) |
DK (1) | DK175037B1 (zh) |
HU (1) | HU198709B (zh) |
SU (1) | SU1701110A3 (zh) |
WO (1) | WO1988007993A1 (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU198709B (en) * | 1987-04-08 | 1989-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing quinoline-carboxylic acid derivatives |
HU203746B (en) * | 1988-12-22 | 1991-09-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing quinoline-carboxylic acid derivatives |
JPH0778065B2 (ja) * | 1990-07-06 | 1995-08-23 | 杏林製薬株式会社 | (6,7―置換―8―アルコキシ―1―シクロプロピル―1,4―ジヒドロ―4―オキソ―3―キノリンカルボン酸―o▲上3▼,o▲上4▼)ビス(アシルオキシ―o)ホウ素化合物及びその塩並びにその製造方法 |
GB9118183D0 (en) * | 1991-08-23 | 1991-10-09 | Solanki Kishor K | Imaging of infections |
US5440061A (en) * | 1994-03-29 | 1995-08-08 | The Procter & Gamble Company | Hydrolysis of methyl esters in dimethylsulfoxide for production of fatty acids |
NZ260530A (en) * | 1994-05-16 | 1997-06-24 | Nigel Paul Maynard | Organoborate complexes of divalent metal; use as timber treament agents |
ES2092963B1 (es) * | 1995-04-12 | 1997-12-16 | Sint Quimica Sa | Procedimiento para la preparacion del acido 1-ciclopropil-6-fluoro-1, 4-dihidro-7-(1s,4s)-5-metil-2,5-diazabiciclo(2.2.1) hept-2-il)-4-oxo-3-quinolincarboxilico y sus sales. |
ES2095809B1 (es) * | 1995-07-27 | 1997-12-16 | Sint Quimica Sa | Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales. |
CN101195614B (zh) * | 2006-12-04 | 2011-10-26 | 河南康泰制药集团公司 | 一种巴洛沙星的制备及纯化方法 |
CN101671302B (zh) * | 2008-12-30 | 2011-03-30 | 广东海康兽药有限公司 | 禽畜用抗菌药恩诺沙星的生产工艺 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3033157A1 (de) * | 1980-09-03 | 1982-04-01 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
DE3142854A1 (de) * | 1981-10-29 | 1983-05-11 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
JPS5980683A (ja) * | 1982-10-30 | 1984-05-10 | Koei Chem Co Ltd | 6−フルオロ−1,8−ナフチリジン誘導体およびその製造法 |
JPS59122470A (ja) * | 1982-12-27 | 1984-07-14 | Dai Ichi Seiyaku Co Ltd | キノリン−3−カルボン酸誘導体の製造法 |
JPS6075489A (ja) * | 1983-10-03 | 1985-04-27 | Dai Ichi Seiyaku Co Ltd | ホウ素キレ−ト化合物 |
JPS6078986A (ja) * | 1983-10-07 | 1985-05-04 | Dai Ichi Seiyaku Co Ltd | オキサジン誘導体の製法 |
JPS60126290A (ja) * | 1983-12-13 | 1985-07-05 | Dai Ichi Seiyaku Co Ltd | ホウ素キレ−ト化合物の製造法 |
HU196782B (en) * | 1985-12-09 | 1989-01-30 | Chinoin Gyogyszer Es Vegyeszet | Process for production of quinoline carbonic acid |
HU196218B (en) * | 1985-12-09 | 1988-10-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing quinoline carboxylic acid boric acid anhydrides |
HU196415B (en) * | 1985-12-09 | 1988-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing quinoline carboxylic acid boric acid anhydrides |
US4940710A (en) * | 1986-01-17 | 1990-07-10 | American Cyanamid Company | 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
SI8810667A8 (en) * | 1987-04-08 | 1996-04-30 | Chinoin Gyogyszer Es Vegyeszet | Anhydride of quinoline carboxylic acid of boron acid and process for their production. |
HU198709B (en) * | 1987-04-08 | 1989-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing quinoline-carboxylic acid derivatives |
JP2693988B2 (ja) * | 1987-06-24 | 1997-12-24 | キノイン ギオギスゼル エス ベギエスゼチ テルメケク ギヤラ アールティー. | キノリンカルボン酸誘導体の製造方法 |
JPS6419069A (en) * | 1987-07-14 | 1989-01-23 | Dainippon Pharmaceutical Co | Production of polyhalogenoquinoline derivative |
-
1987
- 1987-04-08 HU HU871505A patent/HU198709B/hu unknown
-
1988
- 1988-04-07 CN CN88101907A patent/CN1025616C/zh not_active Expired - Lifetime
- 1988-04-07 DD DD88314509A patent/DD269848A5/de not_active IP Right Cessation
- 1988-04-08 DE DE3854109T patent/DE3854109T2/de not_active Expired - Lifetime
- 1988-04-08 AU AU15721/88A patent/AU612648B2/en not_active Expired
- 1988-04-08 WO PCT/HU1988/000019 patent/WO1988007993A1/en active IP Right Grant
- 1988-04-08 AT AT88903335T patent/ATE124687T1/de not_active IP Right Cessation
- 1988-04-08 EP EP88903335A patent/EP0309537B1/en not_active Expired - Lifetime
- 1988-04-08 CS CS242088A patent/CS274460B2/cs not_active IP Right Cessation
- 1988-04-08 JP JP63503085A patent/JP2693987B2/ja not_active Expired - Lifetime
- 1988-04-08 US US07/290,105 patent/US5091530A/en not_active Expired - Lifetime
- 1988-12-07 DK DK198806822A patent/DK175037B1/da not_active IP Right Cessation
- 1988-12-07 SU SU884613033A patent/SU1701110A3/ru active
-
1991
- 1991-09-06 US US07/756,345 patent/US5300644A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN1025616C (zh) | 1994-08-10 |
US5091530A (en) | 1992-02-25 |
US5300644A (en) | 1994-04-05 |
DD269848A5 (de) | 1989-07-12 |
EP0309537B1 (en) | 1995-07-05 |
JP2693987B2 (ja) | 1997-12-24 |
DE3854109T2 (de) | 1995-11-30 |
ATE124687T1 (de) | 1995-07-15 |
DK175037B1 (da) | 2004-05-10 |
SU1701110A3 (ru) | 1991-12-23 |
AU1572188A (en) | 1988-11-04 |
DK682288A (da) | 1988-12-07 |
DE3854109D1 (de) | 1995-08-10 |
CS242088A2 (en) | 1990-09-12 |
HUT46686A (en) | 1988-11-28 |
HU198709B (en) | 1989-11-28 |
EP0309537A1 (en) | 1989-04-05 |
JPH01503301A (ja) | 1989-11-09 |
DK682288D0 (da) | 1988-12-07 |
CN88101907A (zh) | 1988-10-26 |
WO1988007993A1 (en) | 1988-10-20 |
AU612648B2 (en) | 1991-07-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0342675B1 (en) | Novel quinolonecarboxylic acid derivatives | |
JP2520549B2 (ja) | フルオロシクロプロピルアミノアクリル酸エステル誘導体 | |
JPH0778065B2 (ja) | (6,7―置換―8―アルコキシ―1―シクロプロピル―1,4―ジヒドロ―4―オキソ―3―キノリンカルボン酸―o▲上3▼,o▲上4▼)ビス(アシルオキシ―o)ホウ素化合物及びその塩並びにその製造方法 | |
CS274460B2 (en) | Method of 1-cyclopropyl-7-substituted-6-fluor-4-oxo-1,4-dihydroquinoline-3-carboxylic acid's derivatives production | |
KR970005911B1 (ko) | 퀴놀린 카복실산 유도체를 제조하는 제조방법 | |
US4981966A (en) | Process for the preparation of quinoline carboxylic acids | |
CS261250B2 (en) | Method of 1-methylaminoquinolinecarboxyl acid's and its derivatives production | |
KR970005910B1 (ko) | 퀴놀린 카복실산의 제조방법 | |
KR0146335B1 (ko) | 퀴놀린 카르복실산 유도체의 제조방법 | |
US5380845A (en) | Process for the preparation of quinoline carboxylic acid derivatives | |
RU2049783C1 (ru) | Способ получения производных хинолинкарбоновых кислот или их фармацевтически приемлемых солей | |
US5284950A (en) | Process for the preparation of quinoline carboxyolic acids | |
RU2044734C1 (ru) | Способ получения хинолинкарбоновой кислоты или ее фармацевтически приемлемых солей и соединение | |
EP0195135B1 (en) | A process for the preparation of quinoline carboxylic acid derivatives | |
KR900000554B1 (ko) | 퀴놀린카르복실산 유도체의 제조방법 | |
IE58031B1 (en) | A process for the preparation of quinoline carboxylic acid derivatives | |
CZ97496A3 (en) | Process for preparing 1-cyclopropyl-6-fluoro-1, 4-dihydro-7-£(1s, 4s)|-5-methyl-2,5-diazabicyclo £2.2.1|hept-2-yl|-4-oxo-3-quinolinecarboxylic acid and salts thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
IF00 | In force as of 2000-06-30 in czech republic | ||
MK4A | Patent expired |
Effective date: 20080408 |