CS258492B2 - Method of new dihydropyridine-lactols production - Google Patents

Method of new dihydropyridine-lactols production Download PDF

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Publication number
CS258492B2
CS258492B2 CS867923A CS792386A CS258492B2 CS 258492 B2 CS258492 B2 CS 258492B2 CS 867923 A CS867923 A CS 867923A CS 792386 A CS792386 A CS 792386A CS 258492 B2 CS258492 B2 CS 258492B2
Authority
CS
Czechoslovakia
Prior art keywords
alkyl
opt
alkyl group
substd
carbon atoms
Prior art date
Application number
CS867923A
Other languages
Czech (cs)
English (en)
Other versions
CS792386A2 (en
Inventor
Siegfried Goldmann
Friedrich Bossert
Hans J Ahr
Hilmar Bischoff
Walter Puls
Dieter Petzinna
Klaus Schlossmann
Joachim Bender
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Priority to CS873846A priority Critical patent/CS258499B2/cs
Publication of CS792386A2 publication Critical patent/CS792386A2/cs
Publication of CS258492B2 publication Critical patent/CS258492B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
CS867923A 1986-01-17 1986-11-03 Method of new dihydropyridine-lactols production CS258492B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS873846A CS258499B2 (cs) 1986-01-17 1987-05-27 Způsob výroby nových dihydropyridinlaktolů

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863601226 DE3601226A1 (de) 1986-01-17 1986-01-17 Dihydropyridinlactole, verfahren zur herstellung und ihre verwendung in arzneimitteln

Publications (2)

Publication Number Publication Date
CS792386A2 CS792386A2 (en) 1988-01-15
CS258492B2 true CS258492B2 (en) 1988-08-16

Family

ID=6292033

Family Applications (1)

Application Number Title Priority Date Filing Date
CS867923A CS258492B2 (en) 1986-01-17 1986-11-03 Method of new dihydropyridine-lactols production

Country Status (25)

Country Link
US (1) US4721719A (xx)
EP (1) EP0235347B1 (xx)
JP (1) JPH0762018B2 (xx)
KR (1) KR870007179A (xx)
CN (2) CN1019488B (xx)
AT (1) ATE68184T1 (xx)
AU (1) AU587068B2 (xx)
CA (1) CA1293508C (xx)
CS (1) CS258492B2 (xx)
DD (1) DD268945A5 (xx)
DE (2) DE3601226A1 (xx)
DK (1) DK161252C (xx)
EG (1) EG18031A (xx)
ES (1) ES2009209A6 (xx)
FI (1) FI870151A (xx)
GR (1) GR862107B (xx)
HU (1) HU196804B (xx)
IL (1) IL81258A (xx)
NO (1) NO164597C (xx)
NZ (1) NZ217308A (xx)
PH (1) PH23676A (xx)
PL (2) PL149694B1 (xx)
PT (1) PT84120B (xx)
SU (1) SU1440345A3 (xx)
ZA (1) ZA865968B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3410645A1 (de) * 1984-03-23 1985-09-26 Bayer Ag, 5090 Leverkusen L-alkylsubstituierte 1,4-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
JP2594809B2 (ja) * 1988-04-02 1997-03-26 日本ゼオン株式会社 タイヤトレッド用ゴム組成物
JP4860050B2 (ja) * 2001-04-23 2012-01-25 富士重工業株式会社 溶断装置による穿孔方法及び溶断装置
AU2004272078A1 (en) * 2003-09-10 2005-03-24 Synta Pharmaceuticals Corp. Dihydropyridine compounds for treating or preventing metabolic disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0080220B1 (en) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
EP0111455A3 (de) * 1982-12-10 1984-07-25 Ciba-Geigy Ag Ungesättigte Lactone
DE3343658A1 (de) * 1983-12-02 1985-06-13 Bayer Ag, 5090 Leverkusen Hydroxy-tetrahydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
HUT45255A (en) 1988-06-28
GR862107B (en) 1986-12-30
ATE68184T1 (de) 1991-10-15
EP0235347A3 (en) 1987-11-19
ES2009209A6 (es) 1989-09-16
IL81258A (en) 1991-06-10
DK161252B (da) 1991-06-17
US4721719A (en) 1988-01-26
NZ217308A (en) 1988-11-29
DE3681913D1 (de) 1991-11-14
JPH0762018B2 (ja) 1995-07-05
EP0235347A2 (de) 1987-09-09
IL81258A0 (en) 1987-08-31
CN86106735A (zh) 1987-07-29
DD268945A5 (de) 1989-06-14
DK372586A (da) 1987-07-18
PT84120B (pt) 1989-07-31
CA1293508C (en) 1991-12-24
PL149184B1 (en) 1990-01-31
CN1019488B (zh) 1992-12-16
KR870007179A (ko) 1987-08-17
DK161252C (da) 1992-01-06
NO164597B (no) 1990-07-16
PH23676A (en) 1989-09-27
DK372586D0 (da) 1986-08-05
EG18031A (en) 1991-11-30
NO865324L (no) 1987-07-20
PL271190A1 (en) 1989-01-23
HU196804B (en) 1989-01-30
PT84120A (en) 1987-02-01
FI870151A (fi) 1987-07-18
PL149694B1 (en) 1990-03-31
FI870151A0 (fi) 1987-01-15
AU587068B2 (en) 1989-08-03
NO164597C (no) 1990-10-24
JPS62169790A (ja) 1987-07-25
SU1440345A3 (ru) 1988-11-23
AU6323386A (en) 1987-07-23
ZA865968B (en) 1987-03-25
EP0235347B1 (de) 1991-10-09
CS792386A2 (en) 1988-01-15
CN1061528A (zh) 1992-06-03
PL261050A1 (en) 1988-07-07
DE3601226A1 (de) 1987-07-23

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