CS245756B2 - Production method of n-alkylsubstituted amides of cinnamic acid - Google Patents

Production method of n-alkylsubstituted amides of cinnamic acid Download PDF

Info

Publication number
CS245756B2
CS245756B2 CS77695A CS69577A CS245756B2 CS 245756 B2 CS245756 B2 CS 245756B2 CS 77695 A CS77695 A CS 77695A CS 69577 A CS69577 A CS 69577A CS 245756 B2 CS245756 B2 CS 245756B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
acid
process according
alkyl
trans
Prior art date
Application number
CS77695A
Other languages
Czech (cs)
English (en)
Inventor
Eugene Grivsky
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of CS245756B2 publication Critical patent/CS245756B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/618Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
CS77695A 1976-02-03 1977-02-02 Production method of n-alkylsubstituted amides of cinnamic acid CS245756B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB416976 1976-02-03
GB4168/76A GB1568401A (en) 1976-02-03 1976-02-03 Biologically active amides
GB417076 1976-02-03
US71213476A 1976-08-06 1976-08-06
US71213576A 1976-08-06 1976-08-06
US71231876A 1976-08-06 1976-08-06

Publications (1)

Publication Number Publication Date
CS245756B2 true CS245756B2 (en) 1986-10-16

Family

ID=27546490

Family Applications (2)

Application Number Title Priority Date Filing Date
CS77695A CS245756B2 (en) 1976-02-03 1977-02-02 Production method of n-alkylsubstituted amides of cinnamic acid
CS777652A CS245758B2 (en) 1976-02-03 1977-02-02 Production method of n-alkylsubstituted amides of cinnamic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS777652A CS245758B2 (en) 1976-02-03 1977-02-02 Production method of n-alkylsubstituted amides of cinnamic acid

Country Status (20)

Country Link
JP (1) JPS6056700B2 (Direct)
AR (1) AR218865A1 (Direct)
AT (1) AT363926B (Direct)
BE (1) BE851020A (Direct)
CA (1) CA1109076A (Direct)
CH (1) CH634551A5 (Direct)
CS (2) CS245756B2 (Direct)
DD (1) DD130349A5 (Direct)
DE (1) DE2704365C2 (Direct)
DK (1) DK43177A (Direct)
FI (1) FI69625C (Direct)
FR (1) FR2340303A1 (Direct)
GB (1) GB1568401A (Direct)
GR (1) GR66474B (Direct)
HU (1) HU175435B (Direct)
IE (1) IE44862B1 (Direct)
IL (1) IL51373A (Direct)
NL (1) NL7701088A (Direct)
PL (2) PL119314B1 (Direct)
SE (2) SE436870B (Direct)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0714871B2 (ja) * 1989-02-02 1995-02-22 大正製薬株式会社 筋弛緩剤
DE19931116A1 (de) * 1999-07-06 2001-01-11 Bayer Ag Verfahren zur Herstellung von Phenethylaminen und neue chemische Verbindungen
CN104513172B (zh) * 2013-09-30 2018-02-02 天士力医药集团股份有限公司 含有三氟甲基的酰胺生物碱、制备方法及其药物用途
CN104432097B (zh) * 2014-12-16 2016-08-17 广州渔夫堡医药科技有限公司 一种缓解体力疲劳的天然增补剂

Also Published As

Publication number Publication date
FR2340303A1 (fr) 1977-09-02
PL195740A1 (pl) 1979-05-07
SE436870B (sv) 1985-01-28
DE2704365A1 (de) 1977-08-04
DK43177A (da) 1977-08-04
CH634551A5 (en) 1983-02-15
AR218865A1 (es) 1980-07-15
DD130349A5 (de) 1978-03-22
GB1568401A (en) 1980-05-29
PL119716B1 (en) 1982-01-30
FI69625B (fi) 1985-11-29
JPS6056700B2 (ja) 1985-12-11
ATA65277A (de) 1981-02-15
HU175435B (hu) 1980-07-28
SE8300432D0 (sv) 1983-01-28
FI69625C (fi) 1986-03-10
GR66474B (Direct) 1981-03-23
AT363926B (de) 1981-09-10
IL51373A (en) 1981-12-31
SE7701107L (sv) 1977-08-04
PL119314B1 (en) 1981-12-31
NL7701088A (nl) 1977-08-05
JPS52116437A (en) 1977-09-29
DE2704365C2 (de) 1986-03-20
FI770365A7 (Direct) 1977-08-04
IE44862L (en) 1977-08-03
IE44862B1 (en) 1982-04-21
CS245758B2 (en) 1986-10-16
BE851020A (fr) 1977-08-02
SE8300432L (sv) 1983-01-28
CA1109076A (en) 1981-09-15
IL51373A0 (en) 1977-04-29
FR2340303B1 (Direct) 1979-04-13

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