CS241484B2 - Method of 3- (4- )2-hydroxy-3-isopropyl-aminopropoxy (phenyl)alkane acids production - Google Patents

Method of 3- (4- )2-hydroxy-3-isopropyl-aminopropoxy (phenyl)alkane acids production Download PDF

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Publication number
CS241484B2
CS241484B2 CS814047A CS404781A CS241484B2 CS 241484 B2 CS241484 B2 CS 241484B2 CS 814047 A CS814047 A CS 814047A CS 404781 A CS404781 A CS 404781A CS 241484 B2 CS241484 B2 CS 241484B2
Authority
CS
Czechoslovakia
Prior art keywords
phenyl
hydroxy
iii
formulas
compounds
Prior art date
Application number
CS814047A
Other languages
Czech (cs)
English (en)
Other versions
CS404781A2 (en
Inventor
Enar I Carlsson
Bill B R Gustafsson
Bo T Lundgren
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of CS404781A2 publication Critical patent/CS404781A2/cs
Publication of CS241484B2 publication Critical patent/CS241484B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
CS814047A 1980-06-02 1981-06-01 Method of 3- (4- )2-hydroxy-3-isopropyl-aminopropoxy (phenyl)alkane acids production CS241484B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8004087A SE8004087L (sv) 1980-06-02 1980-06-02 Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ...

Publications (2)

Publication Number Publication Date
CS404781A2 CS404781A2 (en) 1985-06-13
CS241484B2 true CS241484B2 (en) 1986-03-13

Family

ID=20341101

Family Applications (1)

Application Number Title Priority Date Filing Date
CS814047A CS241484B2 (en) 1980-06-02 1981-06-01 Method of 3- (4- )2-hydroxy-3-isopropyl-aminopropoxy (phenyl)alkane acids production

Country Status (25)

Country Link
EP (1) EP0041491B1 (da)
JP (1) JPS5724335A (da)
KR (1) KR850000869B1 (da)
AT (1) ATE11529T1 (da)
AU (1) AU548290B2 (da)
CS (1) CS241484B2 (da)
DD (1) DD159328A5 (da)
DE (1) DE3168595D1 (da)
DK (1) DK154208C (da)
ES (1) ES8300679A1 (da)
FI (1) FI71725C (da)
GR (1) GR74571B (da)
HU (1) HU184860B (da)
IE (1) IE53801B1 (da)
LU (2) LU88317I2 (da)
MY (1) MY8600219A (da)
NL (1) NL930102I2 (da)
NO (1) NO151282C (da)
NZ (1) NZ197237A (da)
PH (1) PH16135A (da)
PL (1) PL135823B1 (da)
PT (1) PT73111B (da)
SE (1) SE8004087L (da)
SU (1) SU1156592A3 (da)
ZA (1) ZA812981B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4455317A (en) * 1981-06-23 1984-06-19 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4559359A (en) * 1981-06-23 1985-12-17 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4454154A (en) * 1981-06-23 1984-06-12 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4578403A (en) * 1981-06-23 1986-03-25 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4829086A (en) * 1984-03-14 1989-05-09 Bodor Nicholas S Soft β-adrenergic blocking agents
US5135926A (en) * 1984-03-14 1992-08-04 Bodor Nicholas S Soft β-adrenergic blocking agents
DE3579203D1 (de) * 1984-03-14 1990-09-20 Nicholas S Bodor Sanfte beta-adrenergische blockierende agenzien.
US5334601A (en) * 1984-03-14 1994-08-02 Bodor Nicholas S Soft β-adrenergic blocking agents
US5202347A (en) * 1984-03-14 1993-04-13 Bodor Nicholas S Soft β-adrenergic blocking agents
JPH0720861B2 (ja) * 1984-04-09 1995-03-08 ザ デュポン マーク ファーマソウテイカル カンパニー 心臓障害の処置または予防用の医薬組成物および方法
WO1988001614A1 (en) * 1986-09-02 1988-03-10 E.I. Du Pont De Nemours And Company RESOLUTION OF dl-METHYL 3-[4-(2-HYDROXY-3-ISOPROPYLAMINO)PROPOXY]PHENYLPROPIONATE [(dl-ESMOLOL)]
US5274002A (en) * 1987-04-14 1993-12-28 Warner-Lambert Company Trisubstituted phenyl analogs having activity for congestive heart failure
CA2015730C (en) * 1989-05-12 1997-10-07 Sadahiko Iguchi Esters of phenylalkanoic acid
US5232948A (en) * 1990-09-10 1993-08-03 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted monocyclic aryl compounds exhibiting selective leukotriene b4 antagonist activity
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US8404896B2 (en) 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
AU2014255381A1 (en) 2013-04-17 2015-10-08 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2015115270A1 (ja) * 2014-01-29 2015-08-06 住友ベークライト株式会社 ブレーキパッドおよびキャリパ装置
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
MX2021008533A (es) 2019-01-18 2021-08-19 Astrazeneca Ab Inhibidores de la pcsk9 y metodos de uso de los mismos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB673413A (en) * 1950-03-22 1952-06-04 Rhone Poulenc Sa New local anaesthetics which are substituted benzoic esters and processes for making the same
CH512427A (de) * 1967-12-18 1971-09-15 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen
GB1285038A (en) 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives
SE354851B (da) * 1970-02-18 1973-03-26 Haessle Ab
FR2132570B1 (da) 1971-04-09 1974-08-02 Lipha
PT66890B (fr) * 1976-08-21 1979-01-25 Hexachimie Procede pour la preparation des aryloxy-1 amino-3 propanol-2

Also Published As

Publication number Publication date
AU548290B2 (en) 1985-12-05
AU7116681A (en) 1982-12-02
IE53801B1 (en) 1989-03-01
FI811671L (fi) 1981-12-03
ES502656A0 (es) 1982-11-01
NO151282B (no) 1984-12-03
NO151282C (no) 1985-03-13
CS404781A2 (en) 1985-06-13
PT73111B (en) 1983-05-11
ATE11529T1 (de) 1985-02-15
GR74571B (da) 1984-06-29
NL930102I1 (nl) 1993-10-01
DK239581A (da) 1981-12-03
DD159328A5 (de) 1983-03-02
JPS639501B2 (da) 1988-02-29
HU184860B (en) 1984-10-29
PL231450A1 (en) 1983-03-28
IE811217L (en) 1981-12-02
NZ197237A (en) 1985-01-31
PH16135A (en) 1983-07-08
JPS5724335A (en) 1982-02-08
SU1156592A3 (ru) 1985-05-15
ES8300679A1 (es) 1982-11-01
FI71725C (fi) 1987-02-09
DK154208C (da) 1989-03-20
DK154208B (da) 1988-10-24
NL930102I2 (nl) 1994-12-01
NO811799L (no) 1981-12-03
PL135823B1 (en) 1985-12-31
EP0041491B1 (en) 1985-01-30
LU88348I2 (fr) 1994-09-09
FI71725B (fi) 1986-10-31
KR830006177A (ko) 1983-09-20
MY8600219A (en) 1986-12-31
EP0041491A1 (en) 1981-12-09
LU88317I2 (fr) 1994-05-04
ZA812981B (en) 1982-05-26
KR850000869B1 (ko) 1985-06-22
PT73111A (en) 1981-07-01
DE3168595D1 (en) 1985-03-14
SE8004087L (sv) 1981-12-03

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