CS241100B2 - Method of diazinethenylphenyloxamic acid preparation - Google Patents

Method of diazinethenylphenyloxamic acid preparation Download PDF

Info

Publication number
CS241100B2
CS241100B2 CS846545A CS654584A CS241100B2 CS 241100 B2 CS241100 B2 CS 241100B2 CS 846545 A CS846545 A CS 846545A CS 654584 A CS654584 A CS 654584A CS 241100 B2 CS241100 B2 CS 241100B2
Authority
CS
Czechoslovakia
Prior art keywords
ethenylphenyl
ethyl
formula
hydrogen
oxamate
Prior art date
Application number
CS846545A
Other languages
Czech (cs)
English (en)
Other versions
CS654584A2 (en
Inventor
Karl G Grozinger
James T Oliver
Original Assignee
Boehringer Ingelheim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd
Publication of CS654584A2 publication Critical patent/CS654584A2/cs
Publication of CS241100B2 publication Critical patent/CS241100B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/08Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/12Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/16Halogen atoms; Nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)
CS846545A 1983-09-01 1984-08-30 Method of diazinethenylphenyloxamic acid preparation CS241100B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52852283A 1983-09-01 1983-09-01

Publications (2)

Publication Number Publication Date
CS654584A2 CS654584A2 (en) 1985-07-16
CS241100B2 true CS241100B2 (en) 1986-03-13

Family

ID=24106021

Family Applications (1)

Application Number Title Priority Date Filing Date
CS846545A CS241100B2 (en) 1983-09-01 1984-08-30 Method of diazinethenylphenyloxamic acid preparation

Country Status (22)

Country Link
EP (1) EP0137979B1 (de)
JP (1) JPS60142968A (de)
KR (1) KR900001217B1 (de)
AT (1) ATE38224T1 (de)
AU (1) AU569541B2 (de)
CA (1) CA1219873A (de)
CS (1) CS241100B2 (de)
DD (1) DD227964A5 (de)
DE (1) DE3474817D1 (de)
DK (1) DK158725C (de)
ES (1) ES8505934A1 (de)
FI (1) FI84477C (de)
GR (1) GR80245B (de)
HU (1) HU192576B (de)
IE (1) IE59035B1 (de)
IL (1) IL72833A (de)
NO (1) NO843477L (de)
NZ (1) NZ209405A (de)
PH (1) PH22753A (de)
PT (1) PT79163B (de)
SU (1) SU1342410A3 (de)
ZA (1) ZA846826B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62145049A (ja) * 1985-12-18 1987-06-29 Mitsubishi Chem Ind Ltd アミノスチリル化合物及びそれを有効成分とするロイコトリエンきつ抗剤
WO1992000963A1 (en) * 1990-07-12 1992-01-23 Yoshitomi Pharmaceutical Industries, Ltd. Styryl compounds and use thereof as medicine
JP2832923B2 (ja) * 1990-07-13 1998-12-09 吉富製薬株式会社 スチリル化合物およびその医薬用途
WO1999035140A1 (en) * 1998-01-12 1999-07-15 Novartis Ag PYRIDINYLPYRIMIDINE AMINES AS IMMUNOGLOBULINE E (IgE) SYNTHESIS INHIBITORS

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1259685A (en) * 1969-04-03 1972-01-12 Soc D Etudes Prod Chimique Amino-pyrimidine derivatives
US3993679A (en) * 1972-12-20 1976-11-23 The Upjohn Company Cyano phenylene dioxamic molecules
US4054666A (en) * 1973-03-23 1977-10-18 American Home Products Corporation Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives
US3953468A (en) * 1974-03-15 1976-04-27 The Upjohn Company 3-Cyano thiophen-2-yl oxamic acid and derivatives
CA1066714A (en) * 1974-06-10 1979-11-20 John B. Wright Pharmaceutical n-phenyloxamic acid derivatives
DE2828091A1 (de) * 1978-06-27 1980-01-10 Boehringer Sohn Ingelheim 4-substituierte thiazoloxamsaeuren sowie ihre salze und ester
JPS5761028A (en) * 1980-09-30 1982-04-13 Sanyo Chem Ind Ltd Formation of heat-insulating primer layer and heat-insulating structure

Also Published As

Publication number Publication date
ATE38224T1 (de) 1988-11-15
IE59035B1 (en) 1993-12-15
KR850002258A (ko) 1985-05-10
CA1219873A (en) 1987-03-31
AU3260084A (en) 1985-03-07
PH22753A (en) 1988-11-28
IE842237L (en) 1985-03-01
EP0137979B1 (de) 1988-10-26
DE3474817D1 (en) 1988-12-01
FI843417A (fi) 1985-03-02
JPS60142968A (ja) 1985-07-29
PT79163A (en) 1984-09-01
IL72833A0 (en) 1984-11-30
SU1342410A3 (ru) 1987-09-30
CS654584A2 (en) 1985-07-16
ES535572A0 (es) 1985-06-16
FI843417A0 (fi) 1984-08-30
HU192576B (en) 1987-06-29
DD227964A5 (de) 1985-10-02
EP0137979A1 (de) 1985-04-24
DK158725B (da) 1990-07-09
NO843477L (no) 1985-03-04
ZA846826B (en) 1986-04-30
KR900001217B1 (ko) 1990-02-28
NZ209405A (en) 1987-05-29
HUT37129A (en) 1985-11-28
PT79163B (en) 1986-11-18
ES8505934A1 (es) 1985-06-16
GR80245B (en) 1985-01-03
AU569541B2 (en) 1988-02-04
FI84477B (fi) 1991-08-30
IL72833A (en) 1987-09-16
FI84477C (fi) 1991-12-10
DK418484A (da) 1985-03-02
DK158725C (da) 1990-12-10
DK418484D0 (da) 1984-08-31

Similar Documents

Publication Publication Date Title
US4886807A (en) Novel pyrimidopyrimidine derivative, process for producing it and pharmaceutical composition
JPH07502742A (ja) Paf−レセプタ拮抗剤としてのアミノ酸誘導体
US4782055A (en) Imidazopyridine compounds useful in the treatment of ulcers
EP3144303B1 (de) 6-substituierte phenoxychromancarboxylsäurederivate
JPH0794455B2 (ja) 双性イオン性二環式化合物およびその塩、溶媒和物、水和物ならびにエステル
GB1588242A (en) N-(tetrazol-5-yl)-salicylamide derivatives
EP0580637A1 (de) Imidazo(4,5-c)pyridoderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende arzneimittel
JPS6216949B2 (de)
US5362744A (en) Tetrazole-substituted urea acat inhibitors
JPS62252780A (ja) 新規なインデノチアゾ−ル誘導体及びその製造法
KR890000487B1 (ko) 비스(피페라지닐 또는 호모피페라지닐)알칸 및 그의 제조방법
CS241100B2 (en) Method of diazinethenylphenyloxamic acid preparation
JPS5829309B2 (ja) コウアレルギ−セイサンカンシキカゴウブツノ セイゾウホウホウ
US4241068A (en) 2-(Pyridyl-amino)-benzoic acids and salts thereof
US4192944A (en) Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents
US4157340A (en) N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives
HUT56340A (en) Process for producing tetrahydronaphthalene derivatives and pharmaceutical compositions comprising such compounds
US4886801A (en) Diazine-ethenylphenyl oxamic acids and esters and salts thereof
US4912135A (en) Amide compounds
US4681884A (en) Diazine-ethenylphenyl oxamic acids and esters and salts thereof
US4788198A (en) Diazine-ethyenylphenyl oxamic acids and esters and salts thereof
US4729995A (en) Pyrimidine 2,4-dioxamate compounds and pharmaceutical compositions
US4720496A (en) Pyridotriazoloquinazolines and triazolopyridoquinazolines useful as antiallergics
US3991188A (en) 3-Alkyl-4-sulfamoyl-aniline therapeutic compositions
KR890004662B1 (ko) 1,8-나프티리딘과 1,5,8-아자나프티리딘 유도체 및 이의 제조방법