IL72833A - (pyrimidinyl,pyridazinyl and pyrazinyl)ethenyl phenyl oxamic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
(pyrimidinyl,pyridazinyl and pyrazinyl)ethenyl phenyl oxamic acid derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL72833A IL72833A IL72833A IL7283384A IL72833A IL 72833 A IL72833 A IL 72833A IL 72833 A IL72833 A IL 72833A IL 7283384 A IL7283384 A IL 7283384A IL 72833 A IL72833 A IL 72833A
- Authority
- IL
- Israel
- Prior art keywords
- carbon atoms
- alkoxy
- hydrogen
- pyridazinyl
- pyrazinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/12—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/16—Halogen atoms; Nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52852283A | 1983-09-01 | 1983-09-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL72833A0 IL72833A0 (en) | 1984-11-30 |
| IL72833A true IL72833A (en) | 1987-09-16 |
Family
ID=24106021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL72833A IL72833A (en) | 1983-09-01 | 1984-08-31 | (pyrimidinyl,pyridazinyl and pyrazinyl)ethenyl phenyl oxamic acid derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0137979B1 (xx) |
| JP (1) | JPS60142968A (xx) |
| KR (1) | KR900001217B1 (xx) |
| AT (1) | ATE38224T1 (xx) |
| AU (1) | AU569541B2 (xx) |
| CA (1) | CA1219873A (xx) |
| CS (1) | CS241100B2 (xx) |
| DD (1) | DD227964A5 (xx) |
| DE (1) | DE3474817D1 (xx) |
| DK (1) | DK158725C (xx) |
| ES (1) | ES8505934A1 (xx) |
| FI (1) | FI84477C (xx) |
| GR (1) | GR80245B (xx) |
| HU (1) | HU192576B (xx) |
| IE (1) | IE59035B1 (xx) |
| IL (1) | IL72833A (xx) |
| NO (1) | NO843477L (xx) |
| NZ (1) | NZ209405A (xx) |
| PH (1) | PH22753A (xx) |
| PT (1) | PT79163B (xx) |
| SU (1) | SU1342410A3 (xx) |
| ZA (1) | ZA846826B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62145049A (ja) * | 1985-12-18 | 1987-06-29 | Mitsubishi Chem Ind Ltd | アミノスチリル化合物及びそれを有効成分とするロイコトリエンきつ抗剤 |
| WO1992000963A1 (en) * | 1990-07-12 | 1992-01-23 | Yoshitomi Pharmaceutical Industries, Ltd. | Styryl compounds and use thereof as medicine |
| JP2832923B2 (ja) * | 1990-07-13 | 1998-12-09 | 吉富製薬株式会社 | スチリル化合物およびその医薬用途 |
| WO1999035140A1 (en) * | 1998-01-12 | 1999-07-15 | Novartis Ag | PYRIDINYLPYRIMIDINE AMINES AS IMMUNOGLOBULINE E (IgE) SYNTHESIS INHIBITORS |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1259685A (en) * | 1969-04-03 | 1972-01-12 | Soc D Etudes Prod Chimique | Amino-pyrimidine derivatives |
| US3993679A (en) * | 1972-12-20 | 1976-11-23 | The Upjohn Company | Cyano phenylene dioxamic molecules |
| US4054666A (en) * | 1973-03-23 | 1977-10-18 | American Home Products Corporation | Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives |
| US3953468A (en) * | 1974-03-15 | 1976-04-27 | The Upjohn Company | 3-Cyano thiophen-2-yl oxamic acid and derivatives |
| CA1066714A (en) * | 1974-06-10 | 1979-11-20 | John B. Wright | Pharmaceutical n-phenyloxamic acid derivatives |
| DE2828091A1 (de) * | 1978-06-27 | 1980-01-10 | Boehringer Sohn Ingelheim | 4-substituierte thiazoloxamsaeuren sowie ihre salze und ester |
| JPS5761028A (en) * | 1980-09-30 | 1982-04-13 | Sanyo Chem Ind Ltd | Formation of heat-insulating primer layer and heat-insulating structure |
-
1984
- 1984-08-23 DE DE8484110036T patent/DE3474817D1/de not_active Expired
- 1984-08-23 EP EP84110036A patent/EP0137979B1/en not_active Expired
- 1984-08-23 AT AT84110036T patent/ATE38224T1/de not_active IP Right Cessation
- 1984-08-29 GR GR80245A patent/GR80245B/el unknown
- 1984-08-29 SU SU843784980A patent/SU1342410A3/ru active
- 1984-08-30 CS CS846545A patent/CS241100B2/cs unknown
- 1984-08-30 PH PH31168A patent/PH22753A/en unknown
- 1984-08-30 FI FI843417A patent/FI84477C/fi not_active IP Right Cessation
- 1984-08-31 ES ES535572A patent/ES8505934A1/es not_active Expired
- 1984-08-31 HU HU843293A patent/HU192576B/hu not_active IP Right Cessation
- 1984-08-31 NZ NZ209405A patent/NZ209405A/en unknown
- 1984-08-31 IL IL72833A patent/IL72833A/xx not_active IP Right Cessation
- 1984-08-31 AU AU32600/84A patent/AU569541B2/en not_active Ceased
- 1984-08-31 PT PT79163A patent/PT79163B/pt not_active IP Right Cessation
- 1984-08-31 DD DD84266851A patent/DD227964A5/de not_active IP Right Cessation
- 1984-08-31 ZA ZA846826A patent/ZA846826B/xx unknown
- 1984-08-31 IE IE223784A patent/IE59035B1/en not_active IP Right Cessation
- 1984-08-31 KR KR1019840005354A patent/KR900001217B1/ko not_active IP Right Cessation
- 1984-08-31 DK DK418484A patent/DK158725C/da not_active IP Right Cessation
- 1984-08-31 CA CA000462219A patent/CA1219873A/en not_active Expired
- 1984-08-31 NO NO843477A patent/NO843477L/no unknown
- 1984-08-31 JP JP59182553A patent/JPS60142968A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0137979A1 (en) | 1985-04-24 |
| FI84477B (fi) | 1991-08-30 |
| PH22753A (en) | 1988-11-28 |
| FI843417A0 (fi) | 1984-08-30 |
| AU569541B2 (en) | 1988-02-04 |
| IE842237L (en) | 1985-03-01 |
| ATE38224T1 (de) | 1988-11-15 |
| AU3260084A (en) | 1985-03-07 |
| HU192576B (en) | 1987-06-29 |
| DK418484D0 (da) | 1984-08-31 |
| NZ209405A (en) | 1987-05-29 |
| KR900001217B1 (ko) | 1990-02-28 |
| KR850002258A (ko) | 1985-05-10 |
| DK158725B (da) | 1990-07-09 |
| SU1342410A3 (ru) | 1987-09-30 |
| HUT37129A (en) | 1985-11-28 |
| IL72833A0 (en) | 1984-11-30 |
| CS654584A2 (en) | 1985-07-16 |
| CA1219873A (en) | 1987-03-31 |
| DK418484A (da) | 1985-03-02 |
| ZA846826B (en) | 1986-04-30 |
| PT79163B (en) | 1986-11-18 |
| FI84477C (fi) | 1991-12-10 |
| NO843477L (no) | 1985-03-04 |
| DK158725C (da) | 1990-12-10 |
| CS241100B2 (en) | 1986-03-13 |
| IE59035B1 (en) | 1993-12-15 |
| DE3474817D1 (en) | 1988-12-01 |
| JPS60142968A (ja) | 1985-07-29 |
| FI843417A (fi) | 1985-03-02 |
| ES535572A0 (es) | 1985-06-16 |
| PT79163A (en) | 1984-09-01 |
| GR80245B (en) | 1985-01-03 |
| ES8505934A1 (es) | 1985-06-16 |
| DD227964A5 (de) | 1985-10-02 |
| EP0137979B1 (en) | 1988-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH | Patent void | ||
| EXP | Patent expired |