CS228920B2 - Method of preparing chloromethylester of penicillanic acid derivative - Google Patents

Method of preparing chloromethylester of penicillanic acid derivative Download PDF

Info

Publication number
CS228920B2
CS228920B2 CS822015A CS201582A CS228920B2 CS 228920 B2 CS228920 B2 CS 228920B2 CS 822015 A CS822015 A CS 822015A CS 201582 A CS201582 A CS 201582A CS 228920 B2 CS228920 B2 CS 228920B2
Authority
CS
Czechoslovakia
Prior art keywords
penicillanic acid
formula
chloromethyl
concentrated
methylene chloride
Prior art date
Application number
CS822015A
Other languages
Czech (cs)
English (en)
Inventor
Vytautas J Jasys
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to CS831991A priority Critical patent/CS228947B2/cs
Priority to CS831992A priority patent/CS228948B2/cs
Publication of CS228920B2 publication Critical patent/CS228920B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
CS822015A 1981-03-23 1982-03-23 Method of preparing chloromethylester of penicillanic acid derivative CS228920B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CS831991A CS228947B2 (cs) 1981-03-23 1983-03-23 Způsob výroby pznicilanoyloxymathylderivátfi 1,1-dioiúdu penicilanové kyseliny
CS831992A CS228948B2 (cs) 1981-03-23 1983-03-23 Způsob výroby penicilanoyloxymethylderivátů 1,1-dioxidu penicilanové kyseliny

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24648281A 1981-03-23 1981-03-23
US06/341,081 US4381263A (en) 1981-03-23 1982-01-25 Process for the preparation of penicillanic acid esters

Publications (1)

Publication Number Publication Date
CS228920B2 true CS228920B2 (en) 1984-05-14

Family

ID=26938011

Family Applications (1)

Application Number Title Priority Date Filing Date
CS822015A CS228920B2 (en) 1981-03-23 1982-03-23 Method of preparing chloromethylester of penicillanic acid derivative

Country Status (27)

Country Link
US (1) US4381263A (fr)
EP (1) EP0061284B1 (fr)
KR (1) KR860001367B1 (fr)
AU (1) AU535417B2 (fr)
BG (2) BG38940A3 (fr)
CA (1) CA1182107A (fr)
CS (1) CS228920B2 (fr)
DD (2) DD202435A5 (fr)
DE (1) DE3270720D1 (fr)
DK (1) DK161969C (fr)
EG (1) EG15908A (fr)
ES (2) ES510658A0 (fr)
FI (1) FI75165C (fr)
GB (1) GB2095665A (fr)
GR (1) GR75939B (fr)
HU (1) HU189124B (fr)
IE (1) IE52813B1 (fr)
IL (1) IL65309A (fr)
IN (1) IN157712B (fr)
MX (1) MX174205B (fr)
NO (2) NO164598C (fr)
NZ (1) NZ200067A (fr)
PH (2) PH18608A (fr)
PL (1) PL130866B1 (fr)
PT (1) PT74622B (fr)
RO (2) RO83707B (fr)
YU (2) YU42762B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704456A (en) * 1985-11-22 1987-11-03 Pfizer Inc. Process for sultamicillin intermediate
JPH01139584A (ja) * 1987-11-25 1989-06-01 Yoshitomi Pharmaceut Ind Ltd ペニシラン酸化合物の製造法
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
ES2057876T3 (es) * 1990-04-13 1994-10-16 Pfizer Procedimiento para la obtencion de un intermedio de sultamicilina.
ES2161602B1 (es) * 1999-04-08 2003-02-16 Asturpharma S A Sintesis de 6-(d-alfa-(bencilidenaminofenilacetamido))penicilanato de 1,1-dioxopenicilanoiloximetilo y analogos. nuevos intermedios para la sintesis de sultamicilina.
CN100384857C (zh) * 2003-11-28 2008-04-30 浙江永宁制药厂 耐β-内酰胺酶的头孢菌素酯化合物及其盐
CN112724162B (zh) * 2020-12-28 2022-06-10 华南农业大学 一种阿莫西林-舒巴坦杂合分子的合成方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5248992B1 (fr) * 1971-07-08 1977-12-14
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
IE49881B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
IE50650B1 (en) * 1979-10-11 1986-06-11 Leo Pharm Prod Ltd Method for producing penicillanic acid derivatives

Also Published As

Publication number Publication date
AU535417B2 (en) 1984-03-22
NO820924L (no) 1982-09-24
PH18487A (en) 1985-08-02
YU42904B (en) 1988-12-31
IL65309A (en) 1985-03-31
FI820993L (fi) 1982-09-24
YU162984A (en) 1985-03-20
NO164598B (no) 1990-07-16
RO87039A2 (fr) 1985-05-20
FI75165B (fi) 1988-01-29
ES519053A0 (es) 1984-03-01
IE820658L (en) 1982-09-23
RO83707A (fr) 1984-03-15
RO87039B1 (ro) 1985-05-31
YU62182A (en) 1985-03-20
BG38940A3 (en) 1986-03-14
CA1182107A (fr) 1985-02-05
PL235577A1 (en) 1983-03-14
NO164598C (no) 1990-10-24
RO83707B (ro) 1984-03-30
DD202435A5 (de) 1983-09-14
DK127282A (da) 1982-09-24
HU189124B (en) 1986-06-30
GR75939B (fr) 1984-08-02
US4381263A (en) 1983-04-26
ES8403133A1 (es) 1984-03-01
BG38938A3 (en) 1986-03-14
YU42762B (en) 1988-12-31
FI75165C (fi) 1988-05-09
DE3270720D1 (en) 1986-05-28
ES8305771A1 (es) 1983-04-16
KR860001367B1 (ko) 1986-09-17
IL65309A0 (en) 1982-05-31
AU8176582A (en) 1982-09-30
IN157712B (fr) 1986-05-24
MX174205B (es) 1994-04-28
PH18608A (en) 1985-08-21
PT74622A (en) 1982-04-01
KR830009111A (ko) 1983-12-17
PL130866B1 (en) 1984-09-29
DK161969B (da) 1991-09-02
ES510658A0 (es) 1983-04-16
NO831057L (no) 1982-09-24
DK161969C (da) 1992-02-03
EG15908A (en) 1990-08-30
EP0061284A1 (fr) 1982-09-29
EP0061284B1 (fr) 1986-04-23
DD209835A5 (de) 1984-05-23
NZ200067A (en) 1985-07-12
PT74622B (en) 1984-11-26
GB2095665A (en) 1982-10-06
IE52813B1 (en) 1988-03-16

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