CS226744B2 - Method of preparing 6,7-diethoxy-1-(4-ethoxy-3-hydroxybenzyl)-3,4-dihydro-isoquinoline - Google Patents

Method of preparing 6,7-diethoxy-1-(4-ethoxy-3-hydroxybenzyl)-3,4-dihydro-isoquinoline Download PDF

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Publication number
CS226744B2
CS226744B2 CS824477A CS447782A CS226744B2 CS 226744 B2 CS226744 B2 CS 226744B2 CS 824477 A CS824477 A CS 824477A CS 447782 A CS447782 A CS 447782A CS 226744 B2 CS226744 B2 CS 226744B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compound
acid
salt
physiologically acceptable
Prior art date
Application number
CS824477A
Other languages
Czech (cs)
English (en)
Inventor
Csaba Dr Szantay
Gyoergy Dr Kalaus
Agoston Dr David
Peter Dr Gyoery
Laszlo Dr Szekeres
Gyula Dr Papp
Va Dr Udvary
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS226744B2 publication Critical patent/CS226744B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS824477A 1981-06-16 1982-06-16 Method of preparing 6,7-diethoxy-1-(4-ethoxy-3-hydroxybenzyl)-3,4-dihydro-isoquinoline CS226744B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811768A HU183479B (en) 1981-06-16 1981-06-16 Process for producing new 6,7-diethoxy-1-aracket-4-ethoxy-3-hydroxy-benzyl-bracket closed-3,4-dihydroisoquinolin

Publications (1)

Publication Number Publication Date
CS226744B2 true CS226744B2 (en) 1984-04-16

Family

ID=10956093

Family Applications (1)

Application Number Title Priority Date Filing Date
CS824477A CS226744B2 (en) 1981-06-16 1982-06-16 Method of preparing 6,7-diethoxy-1-(4-ethoxy-3-hydroxybenzyl)-3,4-dihydro-isoquinoline

Country Status (14)

Country Link
EP (1) EP0067711B1 (hu)
JP (1) JPS584768A (hu)
AT (1) ATE22556T1 (hu)
CA (1) CA1182118A (hu)
CS (1) CS226744B2 (hu)
DD (1) DD202545A5 (hu)
DE (1) DE3273544D1 (hu)
DK (1) DK270282A (hu)
ES (1) ES8304939A1 (hu)
FI (1) FI822133L (hu)
HU (1) HU183479B (hu)
PL (1) PL129718B1 (hu)
SU (1) SU1097621A1 (hu)
YU (1) YU131482A (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579866A (en) * 1984-05-29 1986-04-01 Usv Pharmaceutical Corp. Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents
US4956371A (en) * 1989-09-19 1990-09-11 Euroceltique, S.A. Substituted isoquinolines and methods of using same
GB9322828D0 (en) * 1993-11-05 1993-12-22 Sandoz Ltd Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2368277A1 (fr) * 1976-10-21 1978-05-19 Sobio Lab Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique

Also Published As

Publication number Publication date
YU131482A (en) 1984-12-31
SU1097621A1 (ru) 1984-06-15
PL236951A1 (en) 1983-02-14
ES514256A0 (es) 1983-04-16
JPS584768A (ja) 1983-01-11
ES8304939A1 (es) 1983-04-16
EP0067711A2 (en) 1982-12-22
FI822133L (fi) 1982-12-17
CA1182118A (en) 1985-02-05
FI822133A0 (fi) 1982-06-14
PL129718B1 (en) 1984-06-30
EP0067711A3 (en) 1983-02-23
DE3273544D1 (de) 1986-11-06
ATE22556T1 (de) 1986-10-15
HU183479B (en) 1984-05-28
EP0067711B1 (en) 1986-10-01
DD202545A5 (de) 1983-09-21
DK270282A (da) 1982-12-17

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