FR2368277A1 - Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique - Google Patents
Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytiqueInfo
- Publication number
- FR2368277A1 FR2368277A1 FR7631658A FR7631658A FR2368277A1 FR 2368277 A1 FR2368277 A1 FR 2368277A1 FR 7631658 A FR7631658 A FR 7631658A FR 7631658 A FR7631658 A FR 7631658A FR 2368277 A1 FR2368277 A1 FR 2368277A1
- Authority
- FR
- France
- Prior art keywords
- isoquinoleine
- vasoactive
- new hydrogen
- spasmolytic activity
- hydrogen derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
Composés représentés par la formule générale :
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7631658A FR2368277A1 (fr) | 1976-10-21 | 1976-10-21 | Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique |
DE19782817083 DE2817083A1 (de) | 1976-10-21 | 1978-04-19 | Benzylisochinolin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate |
AT284478A AT356110B (de) | 1976-10-21 | 1978-04-20 | Verfahren zur herstellung von neuen benzyliso- chinolinderivaten und ihren saeureadditions- salzen |
JP4678578A JPS54141786A (en) | 1976-10-21 | 1978-04-20 | Hydrogenated benzylisoquinoline derivatives* their manufacture*medical composition containing them and intermediate compounds for their manufacture |
BE186976A BE866208A (fr) | 1976-10-21 | 1978-04-20 | Derives de l'isoquinoleine hydrogenee |
NL7804202A NL7804202A (nl) | 1976-10-21 | 1978-04-20 | Gehydrogeneerde benzylisochinoline derivaten met spas- molytische en bloeddrukverlagende werking, werkwijze ter bereiding van deze verbindingen alsmede farmaceu- tisch preparaat dat een zodanige verbinding bevat. |
CH425478A CH642632A5 (de) | 1976-10-21 | 1978-04-20 | Benzylisochinolin-derivate, verfahren zu ihrer herstellung und die verwendung dieser verbindungen in arzneipraeparaten. |
US06/300,957 US4442108A (en) | 1976-10-21 | 1981-09-10 | Hydrogenated isoquinolines and peripheral vascular disease treating compositions thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7631658A FR2368277A1 (fr) | 1976-10-21 | 1976-10-21 | Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2368277A1 true FR2368277A1 (fr) | 1978-05-19 |
FR2368277B1 FR2368277B1 (fr) | 1979-02-23 |
Family
ID=9179024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7631658A Granted FR2368277A1 (fr) | 1976-10-21 | 1976-10-21 | Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique |
Country Status (8)
Country | Link |
---|---|
US (1) | US4442108A (fr) |
JP (1) | JPS54141786A (fr) |
AT (1) | AT356110B (fr) |
BE (1) | BE866208A (fr) |
CH (1) | CH642632A5 (fr) |
DE (1) | DE2817083A1 (fr) |
FR (1) | FR2368277A1 (fr) |
NL (1) | NL7804202A (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0142070A1 (fr) * | 1983-10-25 | 1985-05-22 | BASF Aktiengesellschaft | Procédé de préparation de N-méthyl-homovératryl-amine |
EP0617022A1 (fr) * | 1993-02-25 | 1994-09-28 | Banyu Pharmaceutical Co., Ltd. | 6,7-dialkyl-3,4-dihydroisoquinolin-3-ol, procédé pour sa préparation et procédé utilisant ce composé pour la préparation de 6,7-dialkyl1,2,3,4-tétrahydroisoquinolin-8-ol |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU183479B (en) * | 1981-06-16 | 1984-05-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing new 6,7-diethoxy-1-aracket-4-ethoxy-3-hydroxy-benzyl-bracket closed-3,4-dihydroisoquinolin |
US4956371A (en) * | 1989-09-19 | 1990-09-11 | Euroceltique, S.A. | Substituted isoquinolines and methods of using same |
EP1023269A4 (fr) * | 1997-09-30 | 2001-06-27 | Molecular Design Int | Agonistes de beta3-adrenorecepteurs, compositions d'agonistes et procedes d'utilisation |
US6846492B2 (en) | 2000-02-23 | 2005-01-25 | Ciba Specialty Chemicals Corporation | Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces |
AU2001233760A1 (en) * | 2000-02-23 | 2001-09-03 | Ciba Specialty Chemicals Holding Inc. | Use of phenylethylamine derivatives for the anitmicrobial treatment of surfaces |
US6593341B2 (en) | 2001-03-29 | 2003-07-15 | Molecular Design International, Inc. | β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same |
US6596734B1 (en) | 2002-10-11 | 2003-07-22 | Molecular Design International, Inc. | Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2928769A (en) * | 1957-07-22 | 1960-03-15 | Strong Cobb And Company Inc | Production of controlled release medicaments |
IL33480A (en) * | 1968-12-10 | 1973-03-30 | Tanabe Seiyaku Co | 6,7-diacyloxy-tetrahydro-isoquinolines and their preparation |
HU167246B (fr) * | 1973-01-25 | 1975-09-27 | ||
JPS5734275B2 (fr) * | 1973-07-30 | 1982-07-22 |
-
1976
- 1976-10-21 FR FR7631658A patent/FR2368277A1/fr active Granted
-
1978
- 1978-04-19 DE DE19782817083 patent/DE2817083A1/de active Granted
- 1978-04-20 JP JP4678578A patent/JPS54141786A/ja active Granted
- 1978-04-20 CH CH425478A patent/CH642632A5/de not_active IP Right Cessation
- 1978-04-20 NL NL7804202A patent/NL7804202A/xx not_active Application Discontinuation
- 1978-04-20 BE BE186976A patent/BE866208A/fr not_active IP Right Cessation
- 1978-04-20 AT AT284478A patent/AT356110B/de not_active IP Right Cessation
-
1981
- 1981-09-10 US US06/300,957 patent/US4442108A/en not_active Expired - Lifetime
Non-Patent Citations (1)
Title |
---|
NEANT * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0142070A1 (fr) * | 1983-10-25 | 1985-05-22 | BASF Aktiengesellschaft | Procédé de préparation de N-méthyl-homovératryl-amine |
EP0617022A1 (fr) * | 1993-02-25 | 1994-09-28 | Banyu Pharmaceutical Co., Ltd. | 6,7-dialkyl-3,4-dihydroisoquinolin-3-ol, procédé pour sa préparation et procédé utilisant ce composé pour la préparation de 6,7-dialkyl1,2,3,4-tétrahydroisoquinolin-8-ol |
US5498717A (en) * | 1993-02-25 | 1996-03-12 | Banyu Pharmaceutical Co., Ltd. | 6,7-dialkoxy-3,4-diydroisoquinolin-8-yl compounds |
Also Published As
Publication number | Publication date |
---|---|
ATA284478A (de) | 1979-09-15 |
FR2368277B1 (fr) | 1979-02-23 |
JPS54141786A (en) | 1979-11-05 |
JPS64394B2 (fr) | 1989-01-06 |
DE2817083A1 (de) | 1979-11-15 |
US4442108A (en) | 1984-04-10 |
BE866208A (fr) | 1978-10-20 |
CH642632A5 (de) | 1984-04-30 |
AT356110B (de) | 1980-04-10 |
NL7804202A (nl) | 1979-10-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2384751A1 (fr) | Nouveaux derives de la taurine a activite neuro-musculaire renforcee | |
FR2367741A1 (fr) | Nouveaux mercaptoacylamino-acides | |
FR2372803A1 (fr) | Derives acyles substitues d'amino-acides, a activite anti-hypertensive | |
FI833918A0 (fi) | -karboliner, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska preparat | |
FR2354338A1 (fr) | Acides n-phosphonomethylene-monoaminoalcane-mono- et polyphosphoniques et acides n-phosphonomethylene-diaminoalcane-polyphosphoniques, et leur preparation | |
FR2372817A1 (fr) | Derives d'acides thiazolidinecarboxyliques et d'acides apparentes, utiles comme agents anti-hypertension | |
FR2368277A1 (fr) | Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique | |
FR2387950A1 (fr) | Nouveaux derives de cyclohexene, leur preparation et leur application a la preparation de canthaxanthine | |
FR2369259A1 (fr) | Derives de 3,3-dichloro-2-azetidinone ayant une activite anti-inflammatoire | |
FR2370741A1 (fr) | Nouveaux derives de tetrahydrofuranne a proprietes herbicides | |
FR2375234A1 (fr) | 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylates et leur obtention | |
FR2356650A1 (fr) | Nouveaux derives de pyrazolo(1,5-c)quinazoline et composes apparentes, utiles comme agents anti-allergiques | |
FR2434167A1 (fr) | Derives de l'hexahydro-1,2,3,3a,8,8a pyrrolo indole (2,3,-b) | |
FR2365341A1 (fr) | Derives de l'acide l-(phenyl-3 amino-2 propionyloxy)-2 acetique | |
FR2367742A1 (fr) | Derives d'a-thio-alcanoiques, leur preparation et leur utilisation | |
FR2357558A1 (fr) | 2,6-methano-2h-1-benzoxocines | |
FR2376846A1 (fr) | Nouveaux derives de la piperidine | |
FR2430943A1 (fr) | Nouveaux derives disulfures | |
FR2377999A1 (fr) | Nouveaux derives de cycloalcanecarboxanilide a activite herbicide | |
FR2372839A1 (fr) | Derives d'oxazolidinedione des alcaloides de vinca, a activite antitumorale | |
FR2381030A1 (fr) | Phenylaminomethyl-2 imidazolines et leur preparation | |
FR2362125A1 (fr) | Spiro(cyclopropane-1,2'-indolin)-3'-ones | |
FR2368489A1 (fr) | Derives de la clavuline, leur procede de preparation et leur application en therapeutique | |
FR2354312A2 (fr) | Nouveaux derives de substitution du 1,3-diphenoxypropanol-(2) ainsi que leur procede de fabrication et leur application therapeutique | |
FR2367767A1 (fr) | Nouveaux composes de rifamycine |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |