CS221810B2 - Method of making the new isochinoline derivatives with contanets of sulphur - Google Patents

Method of making the new isochinoline derivatives with contanets of sulphur Download PDF

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Publication number
CS221810B2
CS221810B2 CS804727A CS472780A CS221810B2 CS 221810 B2 CS221810 B2 CS 221810B2 CS 804727 A CS804727 A CS 804727A CS 472780 A CS472780 A CS 472780A CS 221810 B2 CS221810 B2 CS 221810B2
Authority
CS
Czechoslovakia
Prior art keywords
carbon atoms
hydrogen
formula
phenyl
alkoxy
Prior art date
Application number
CS804727A
Other languages
Czech (cs)
English (en)
Inventor
Kalman Takacs
Maria H Pap
Gabor Kovacs
Ilona K Ajzert
Antal Simay
Nagy Peter Literati
Marian E Puskas
Gyula Sebestyen
Istvan Stadler
Zoltan Sumeghy
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS221810B2 publication Critical patent/CS221810B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS804727A 1979-07-02 1980-07-02 Method of making the new isochinoline derivatives with contanets of sulphur CS221810B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1944A HU178454B (en) 1979-07-02 1979-07-02 Process for preparing new isoquinoline derivatives containing sulphur

Publications (1)

Publication Number Publication Date
CS221810B2 true CS221810B2 (en) 1983-04-29

Family

ID=10994753

Family Applications (2)

Application Number Title Priority Date Filing Date
CS804727A CS221810B2 (en) 1979-07-02 1980-07-02 Method of making the new isochinoline derivatives with contanets of sulphur
CS82941A CS221811B2 (en) 1979-07-02 1980-07-02 Method of making the new isochimoline derivatives with contents of sulphur

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS82941A CS221811B2 (en) 1979-07-02 1980-07-02 Method of making the new isochimoline derivatives with contents of sulphur

Country Status (26)

Country Link
US (1) US4373104A (xx)
JP (1) JPS5649365A (xx)
AT (1) AT376664B (xx)
AU (1) AU534697B2 (xx)
BE (1) BE884101A (xx)
BG (2) BG36934A3 (xx)
CH (1) CH651554A5 (xx)
CS (2) CS221810B2 (xx)
DD (1) DD151751A5 (xx)
DE (1) DE3023717A1 (xx)
DK (1) DK160422C (xx)
ES (1) ES8105715A1 (xx)
FI (1) FI76324C (xx)
FR (1) FR2460934A1 (xx)
GB (1) GB2053914B (xx)
GR (1) GR69299B (xx)
HU (1) HU178454B (xx)
IL (1) IL60408A (xx)
IN (1) IN151448B (xx)
NL (1) NL190700C (xx)
NO (1) NO155539C (xx)
PL (2) PL124602B1 (xx)
PT (1) PT71472A (xx)
SE (1) SE455701B (xx)
SU (2) SU936809A3 (xx)
YU (1) YU170480A (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
HU189765B (en) * 1983-10-25 1986-07-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing n-substituted 1-(bis (hydroxy-metiol)-methyl)-isoquinoline-derivatives
HU189764B (en) * 1983-10-25 1986-07-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing 1-(bis (substituted methyl)-methyl)-isoquinoline-derivatives
US4584379A (en) * 1985-01-22 1986-04-22 Merrell Dow Pharmaceuticals Inc. Isoquinoline thromboxane synthetase inhibitors
JPS63236994A (ja) * 1987-03-26 1988-10-03 株式会社三協精機製作所 シ−ルド部材
HU209930B (en) * 1990-11-14 1994-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing of 2-mercapto-2-(1-isoquinolylidene)-acetonitrile derivatives and pharmaceutical compositions comprising them
DE4343683A1 (de) * 1993-12-21 1995-06-22 Boehringer Ingelheim Kg Anellierte Dihydropyridine und deren Verwendung für die Herstellung von pharmazeutischen Zubereitungen
HUP0000920A3 (en) * 2000-02-28 2002-03-28 Sanofi Synthelabo Pde4 inhibitor isoquinolinylidene derivatives, process for their preparation and medicaments containing them

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985649A (en) * 1959-09-17 1961-05-23 Pfizer & Co C Derivatives of thiabenzopyrrocoline, thiabenzopyridocoline and thiazepine
GB1145254A (en) * 1965-03-18 1969-03-12 Bristol Myers Co Novel tetrahydroisoquinoline derivatives and a process for the preparation thereof
GB1127525A (en) * 1966-04-01 1968-09-18 Pfizer Ltd Di- and tetrahydroisoquinoline derivatives
US3389141A (en) * 1966-05-16 1968-06-18 Bristol Myers Co 1-beta-aryloxyethyltetrahydro-isoquinolines
US3389140A (en) * 1966-05-16 1968-06-18 Bristol Myers Co 1-beta-arylaminoethyl-2-methyl-6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinolines
US3455933A (en) * 1966-11-15 1969-07-15 American Home Prod Thiazolo and thiazino isoquinoline derivatives
FR2119989B1 (xx) * 1970-12-29 1975-10-10 Fujisawa Pharmaceutical Co
JPS5516138B2 (xx) * 1971-11-17 1980-04-30
AT333763B (de) * 1972-06-20 1976-12-10 Fujisawa Pharmaceutical Co Verfahren zur herstellung von neuen 1,2,3,4-tetrahydroisochinolinen und deren salzen
HU170680B (xx) * 1973-05-30 1977-08-28
AT351540B (de) * 1974-07-17 1979-07-25 Fujisawa Pharmaceutical Co Verfahren zur herstellung von neuen tetrahydro- isochinolinderivaten und deren salzen

Also Published As

Publication number Publication date
SU936809A3 (ru) 1982-06-15
NL190700C (nl) 1994-07-01
DK160422B (da) 1991-03-11
FI802093A (fi) 1981-01-03
CS221811B2 (en) 1983-04-29
PT71472A (en) 1980-07-01
AU6000180A (en) 1981-02-05
DE3023717C2 (xx) 1991-03-21
NL190700B (nl) 1994-02-01
CH651554A5 (de) 1985-09-30
SE455701B (sv) 1988-08-01
DK160422C (da) 1991-08-19
FR2460934A1 (fr) 1981-01-30
YU170480A (en) 1983-06-30
GB2053914B (en) 1983-04-27
IN151448B (xx) 1983-04-23
SU1047389A3 (ru) 1983-10-07
DD151751A5 (de) 1981-11-04
BE884101A (fr) 1980-11-03
SE8004869L (sv) 1981-01-03
IL60408A (en) 1984-11-30
ES8105715A1 (es) 1981-09-01
ES493569A0 (es) 1981-07-01
AT376664B (de) 1984-12-27
DK284880A (da) 1981-01-03
JPH0131502B2 (xx) 1989-06-26
FI76324B (fi) 1988-06-30
FI76324C (fi) 1988-10-10
JPS5649365A (en) 1981-05-02
PL230938A1 (xx) 1982-03-15
GB2053914A (en) 1981-02-11
GR69299B (xx) 1982-05-13
HU178454B (en) 1982-05-28
ATA334880A (de) 1984-05-15
DE3023717A1 (de) 1981-01-29
PL124602B1 (en) 1983-02-28
NO155539C (no) 1987-04-15
PL126804B1 (en) 1983-08-31
US4373104A (en) 1983-02-08
NL8003803A (nl) 1981-01-06
BG36631A3 (en) 1984-12-16
PL225380A1 (xx) 1981-10-02
NO801982L (no) 1981-01-05
NO155539B (no) 1987-01-05
AU534697B2 (en) 1984-02-09
FR2460934B1 (xx) 1984-12-21
BG36934A3 (en) 1985-02-15

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