CS219950B2 - Method of making the derivatives of the n-phenoxypiperidine - Google Patents
Method of making the derivatives of the n-phenoxypiperidine Download PDFInfo
- Publication number
- CS219950B2 CS219950B2 CS806568A CS656880A CS219950B2 CS 219950 B2 CS219950 B2 CS 219950B2 CS 806568 A CS806568 A CS 806568A CS 656880 A CS656880 A CS 656880A CS 219950 B2 CS219950 B2 CS 219950B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- propoxy
- group
- radical
- formula
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792939292 DE2939292A1 (de) | 1979-09-28 | 1979-09-28 | N-phenoxyalkylpiperidin-derivate, verfahrenn zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS219950B2 true CS219950B2 (en) | 1983-03-25 |
Family
ID=6082088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS806568A CS219950B2 (en) | 1979-09-28 | 1980-09-29 | Method of making the derivatives of the n-phenoxypiperidine |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4348401A (es) |
| EP (1) | EP0026876B1 (es) |
| JP (1) | JPS5668669A (es) |
| AT (1) | ATE2519T1 (es) |
| CA (1) | CA1139759A (es) |
| CS (1) | CS219950B2 (es) |
| DD (1) | DD153117A5 (es) |
| DE (2) | DE2939292A1 (es) |
| ES (1) | ES495412A0 (es) |
| IL (1) | IL61114A0 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3209271A1 (de) * | 1982-03-13 | 1983-09-15 | Boehringer Mannheim Gmbh, 6800 Mannheim | Bicyclische phenolether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| FR2681319B1 (fr) * | 1991-09-12 | 1995-02-17 | Synthelabo | Derives de 1-(phenoxyalkyl)piperidine, leur preparation et leur application en therapeutique. |
| GB9319534D0 (en) * | 1993-09-22 | 1993-11-10 | Boots Co Plc | Therapeutic agents |
| HU215397B (hu) * | 1994-08-29 | 1998-12-28 | Richter Gedeon Vegyészeti Gyár Rt. | (Piperidino-alkil)-aril-éterek, ezeket tartalmazó gyógyszerkészítmények és eljárás ezek előállítására |
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610736B (en) * | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
| ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| IL164007A0 (en) | 2002-03-13 | 2005-12-18 | Janssen Pharmaceutica Nv | New inhibitors of histone deacetylase |
| BR0307599A (pt) | 2002-03-13 | 2005-02-01 | Janssen Pharmaceutica Nv | Derivados de sulfonilamino como inibidores de histona deacetilase |
| ATE398105T1 (de) * | 2002-03-13 | 2008-07-15 | Janssen Pharmaceutica Nv | Carbonylamino- derivativate als neue inhibitoren von histone deacetylase |
| ES2307909T3 (es) * | 2002-03-13 | 2008-12-01 | Janssen Pharmaceutica Nv | Derivados de piperazinil, piperidinil y morfolinil como nuevos inhidbidores de la histona deacetilasa. |
| MX2007001120A (es) | 2004-07-28 | 2007-03-15 | Janssen Pharmaceutica Nv | Derivados de indolil alquil sustituidos como nuevos inhibidores de la histona desacetilasa. |
| RU2396955C2 (ru) * | 2005-04-07 | 2010-08-20 | Тояма Кемикал Ко., Лтд. | Фармацевтическая комбинация и способ применения противогрибкового средства в комбинации |
| EP1885710B1 (en) | 2005-05-18 | 2015-08-19 | Janssen Pharmaceutica N.V. | Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase |
| DE602007001190D1 (de) * | 2006-01-19 | 2009-07-09 | Janssen Pharmaceutica Nv | Aminophenylderivate als neue inhibitoren von histondeacetylase |
| JP5137849B2 (ja) * | 2006-01-19 | 2013-02-06 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ヒストンデアセチラーゼのインヒビターとしての置換インドリル−アルキル−アミノ−誘導体 |
| US8114876B2 (en) | 2006-01-19 | 2012-02-14 | Janssen Pharmaceutica N.V. | Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase |
| US8101616B2 (en) * | 2006-01-19 | 2012-01-24 | Janssen Pharmaceutica N.V. | Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase |
| MX2008014450A (es) | 2006-05-18 | 2009-03-09 | Mannkind Corp | Inhibidores de cinasa intracelular. |
| KR102077864B1 (ko) | 2012-08-01 | 2020-02-14 | 쇼와 덴코 패키징 가부시키가이샤 | 내용물 부착 방지 덮개재 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3255196A (en) * | 1966-06-07 | Phenoxyalkyl piperidine derivatives | ||
| CH411880A (fr) * | 1962-02-28 | 1966-04-30 | Rhone Poulenc Sa | Procédé de préparation de nouveaux dérivés de la pipéridine |
| US3691176A (en) * | 1970-05-25 | 1972-09-12 | Abbott Lab | 1-(4-fluorophenoxypropyl)-4-anilino-piperidines |
| DE2341376A1 (de) * | 1972-08-24 | 1974-03-07 | Ciba Geigy Ag | Piperidin-derivate und verfahren zu ihrer herstellung |
| GB1533383A (en) * | 1974-11-15 | 1978-11-22 | Science Union & Cie | Arylethers and heterocyclic ethers processes for their preparation and pharmaceutical compositions containing them |
| US4027028A (en) * | 1975-11-10 | 1977-05-31 | Science Union Et Cie | Arylethers and pharmaceutical compositions |
| DE2737630A1 (de) * | 1977-08-20 | 1979-03-01 | Boehringer Mannheim Gmbh | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1979
- 1979-09-28 DE DE19792939292 patent/DE2939292A1/de not_active Withdrawn
-
1980
- 1980-09-10 US US06/185,839 patent/US4348401A/en not_active Expired - Lifetime
- 1980-09-23 IL IL61114A patent/IL61114A0/xx unknown
- 1980-09-24 EP EP80105725A patent/EP0026876B1/de not_active Expired
- 1980-09-24 AT AT80105725T patent/ATE2519T1/de not_active IP Right Cessation
- 1980-09-24 DE DE8080105725T patent/DE3062052D1/de not_active Expired
- 1980-09-24 DD DD80224197A patent/DD153117A5/de unknown
- 1980-09-26 ES ES495412A patent/ES495412A0/es active Granted
- 1980-09-26 CA CA000361880A patent/CA1139759A/en not_active Expired
- 1980-09-26 JP JP13415080A patent/JPS5668669A/ja active Pending
- 1980-09-29 CS CS806568A patent/CS219950B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5668669A (en) | 1981-06-09 |
| DE2939292A1 (de) | 1981-04-09 |
| EP0026876A1 (de) | 1981-04-15 |
| EP0026876B1 (de) | 1983-02-16 |
| ES8105729A1 (es) | 1981-06-16 |
| US4348401A (en) | 1982-09-07 |
| ATE2519T1 (de) | 1983-03-15 |
| ES495412A0 (es) | 1981-06-16 |
| DE3062052D1 (en) | 1983-03-24 |
| DD153117A5 (de) | 1981-12-23 |
| IL61114A0 (en) | 1980-11-30 |
| CA1139759A (en) | 1983-01-18 |
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