CS219898B2 - Method of making the pyrimidylchinazoline - Google Patents

Method of making the pyrimidylchinazoline Download PDF

Info

Publication number
CS219898B2
CS219898B2 CS812182A CS218281A CS219898B2 CS 219898 B2 CS219898 B2 CS 219898B2 CS 812182 A CS812182 A CS 812182A CS 218281 A CS218281 A CS 218281A CS 219898 B2 CS219898 B2 CS 219898B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compound
alkyl
alkenyl
halogen
Prior art date
Application number
CS812182A
Other languages
Czech (cs)
English (en)
Inventor
Heinz Bender
Thomas Raabe
Helmut Bohn
Piero Martorrana
Original Assignee
Casseila Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Casseila Ag filed Critical Casseila Ag
Publication of CS219898B2 publication Critical patent/CS219898B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Catching Or Destruction (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CS812182A 1980-03-27 1981-03-25 Method of making the pyrimidylchinazoline CS219898B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803011809 DE3011809A1 (de) 1980-03-27 1980-03-27 Pyrimidyl-chinazoline, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und ihre verwendung

Publications (1)

Publication Number Publication Date
CS219898B2 true CS219898B2 (en) 1983-03-25

Family

ID=6098481

Family Applications (1)

Application Number Title Priority Date Filing Date
CS812182A CS219898B2 (en) 1980-03-27 1981-03-25 Method of making the pyrimidylchinazoline

Country Status (18)

Country Link
EP (1) EP0037495A1 (fi)
JP (1) JPS56150088A (fi)
AR (1) AR227542A1 (fi)
AU (1) AU6877481A (fi)
CA (1) CA1156656A (fi)
CS (1) CS219898B2 (fi)
DD (1) DD157614A5 (fi)
DE (1) DE3011809A1 (fi)
DK (1) DK115581A (fi)
ES (1) ES8202000A1 (fi)
FI (1) FI810778L (fi)
GR (1) GR71870B (fi)
IL (1) IL62495A0 (fi)
NO (1) NO810870L (fi)
PL (2) PL230320A1 (fi)
PT (1) PT72724B (fi)
SU (1) SU1052158A3 (fi)
ZA (1) ZA812034B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61140568A (ja) * 1984-12-14 1986-06-27 Mitsui Petrochem Ind Ltd キナゾリン誘導体及びそれを有効成分とする血圧降下剤
JPS6267077A (ja) * 1985-09-18 1987-03-26 Mitsui Petrochem Ind Ltd キナゾリン誘導体及び医薬
CN102127053A (zh) * 2004-03-15 2011-07-20 武田药品工业株式会社 二肽基肽酶抑制剂
PT1778236E (pt) * 2004-07-02 2010-10-19 Corcept Therapeutics Inc Moduladores do receptor de glucocorticóide de pirimidina modificada
AU2012231265B2 (en) 2011-03-18 2016-07-07 Corcept Therapeutics, Inc. Pyrimidine cyclohexyl glucocorticoid receptor modulators
IL278936B1 (en) 2018-06-04 2024-10-01 Corcept Therapeutics Inc Pyrimidine cyclophenyl glucocorticoid and mineralocorticoid receptor modulators
CA3158745A1 (en) 2019-12-11 2021-06-17 Corcept Therapeutics Incorporated Methods of treating antipsychotic-induced weight gain with miricorilant
WO2021226260A1 (en) 2020-05-06 2021-11-11 Corcept Therapeutics Incorporated Polymorphs of pyrimidine cyclohexyl glucocorticoid receptor modulators
CA3202353A1 (en) 2020-12-21 2022-06-30 Jeffrey Mark Dener Method of preparing pyrimidine cyclohexyl glucocorticoid receptor modulators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2007656B (en) * 1977-11-05 1982-05-19 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
ES500738A0 (es) 1982-01-16
PT72724A (de) 1981-04-01
CA1156656A (en) 1983-11-08
ES8202000A1 (es) 1982-01-16
PL233882A1 (fi) 1982-05-10
DE3011809A1 (de) 1981-10-01
EP0037495A1 (de) 1981-10-14
NO810870L (no) 1981-09-28
FI810778L (fi) 1981-09-28
ZA812034B (en) 1982-05-26
GR71870B (fi) 1983-07-08
AR227542A1 (es) 1982-11-15
AU6877481A (en) 1981-10-01
IL62495A0 (en) 1981-05-20
PT72724B (de) 1982-03-24
PL230320A1 (fi) 1982-03-29
DK115581A (da) 1981-09-28
JPS56150088A (en) 1981-11-20
SU1052158A3 (ru) 1983-10-30
DD157614A5 (de) 1982-11-24

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