CS217955B2 - Method of making the new cis ev.trans 2-aminocyclohexac - Google Patents

Method of making the new cis ev.trans 2-aminocyclohexac Download PDF

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Publication number
CS217955B2
CS217955B2 CS359176A CS359176A CS217955B2 CS 217955 B2 CS217955 B2 CS 217955B2 CS 359176 A CS359176 A CS 359176A CS 359176 A CS359176 A CS 359176A CS 217955 B2 CS217955 B2 CS 217955B2
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CS
Czechoslovakia
Prior art keywords
acid
ethanol
formula
trans
cis
Prior art date
Application number
CS359176A
Other languages
Czech (cs)
English (en)
Inventor
Gabor Bernath
Lajos Gera
Gyoergy Goendoes
Kalman Kovacs
Erzsebet Janvari
Gyula Sebestyen
Zoltan Ecsery
Judit Hermann
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to CS78962A priority Critical patent/CS217957B2/cs
Priority to CS78961A priority patent/CS217956B2/cs
Publication of CS217955B2 publication Critical patent/CS217955B2/cs

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40Acylated substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS359176A 1975-06-02 1976-05-28 Method of making the new cis ev.trans 2-aminocyclohexac CS217955B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CS78962A CS217957B2 (cs) 1975-06-02 1978-02-14 Způsob výroby nových cis popřípadě trans 2-aminocyklohexankarboxylových nebo cis popřípadě trans 2-aminocykIopentankarboxylových.kyselin
CS78961A CS217956B2 (cs) 1975-06-02 1978-02-14 Způsob výroby nových cis popřípadě trans 2-aminocyklohexankarboxylových nebo cis popřípadě trans 2-aminocyklopentankarboxylových kyselin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI001580 HU177576B (en) 1975-06-02 1975-06-02 Process for preparing 2-amino-cyclohexane carboxylic acid,its amides and similar compounds

Publications (1)

Publication Number Publication Date
CS217955B2 true CS217955B2 (en) 1983-02-25

Family

ID=10994566

Family Applications (1)

Application Number Title Priority Date Filing Date
CS359176A CS217955B2 (en) 1975-06-02 1976-05-28 Method of making the new cis ev.trans 2-aminocyclohexac

Country Status (6)

Country Link
AT (2) AT350518B (hu)
CS (1) CS217955B2 (hu)
DE (1) DE2624290A1 (hu)
FR (1) FR2313023A1 (hu)
HU (1) HU177576B (hu)
YU (2) YU129376A (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3125872A1 (de) * 1981-07-01 1983-01-20 Basf Ag, 6700 Ludwigshafen Schiff-basen von aminocycloalkancarbonsaeureestern, verfahren zu ihrer herstellung sowie ihre verwendung als zwischenprodukte
EP0214009A3 (en) * 1985-07-30 1989-01-11 Merck & Co. Inc. Enaminones as potential prodrugs of primary and secondary amines
GB8716278D0 (en) * 1987-07-10 1987-08-19 Fujisawa Pharmaceutical Co Antimicrobial agent
DE4033415A1 (de) * 1990-10-20 1992-04-23 Bayer Ag Antimikrobielle mittel sowie substituierte 2-cyclohexan-1-yl-amin-derivate und deren herstellung
AU673824B2 (en) * 1992-05-29 1996-11-28 Bayer Aktiengesellschaft Cyclopentane- and -pentene-beta-amino acids
US6462076B2 (en) 2000-06-14 2002-10-08 Hoffmann-La Roche Inc. Beta-amino acid nitrile derivatives as cathepsin K inhibitors
US6759428B2 (en) 2001-12-04 2004-07-06 Roche Palo Alto Llc Indole nitriles
CN1315806C (zh) 2001-12-04 2007-05-16 霍夫曼·拉罗奇有限公司 取代的2-氨基-环烷烃甲酰胺和它们作为半胱氨酸蛋白酶抑制剂的用途
WO2004056744A1 (en) * 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
EP1533295A1 (en) * 2003-11-24 2005-05-25 Newron Pharmaceuticals S.p.A. Cyclopentyl Derivatives
JP5014983B2 (ja) 2004-05-07 2012-08-29 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 11−ベータヒドロキシステロイドデヒドロゲナーゼ阻害剤としてのピロリジン−2−オン及びピペリジン−2−オン誘導体
EP1786774B1 (en) 2004-08-30 2009-10-14 Janssen Pharmaceutica N.V. Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
NZ553159A (en) 2004-08-30 2010-05-28 Janssen Pharmaceutica Nv N-Adamantan-2-yl-2-phenoxy-acetamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
DE602005017159D1 (de) 2004-08-30 2009-11-26 Janssen Pharmaceutica Nv Oxysteroid-dehydrogenase-inhibitoren
JP5547753B2 (ja) 2009-02-17 2014-07-16 マクアリスター テクノロジーズ エルエルシー 電気分解の間にガスを捕集するための装置および方法
US8075750B2 (en) 2009-02-17 2011-12-13 Mcalister Technologies, Llc Electrolytic cell and method of use thereof
JP5411299B2 (ja) 2009-02-17 2014-02-12 マクアリスター テクノロジーズ エルエルシー 電解セルおよびその使用方法
US9040012B2 (en) 2009-02-17 2015-05-26 Mcalister Technologies, Llc System and method for renewable resource production, for example, hydrogen production by microbial electrolysis, fermentation, and/or photosynthesis
RU2489523C2 (ru) 2009-02-17 2013-08-10 МАКЭЛИСТЭР ТЕКНОЛОДЖИЗ, ЭлЭлСи Устройство и способ регулирования зародышеобразования во время электролиза

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines
US3647804A (en) * 1970-02-27 1972-03-07 Upjohn Co Cycloalkanecarboxamides
US3770825A (en) * 1970-12-07 1973-11-06 Yeda Res & Dev 2-substituted amino cycloalkylcarboxamides

Also Published As

Publication number Publication date
HU177576B (en) 1981-11-28
YU129376A (en) 1982-08-31
FR2313023A1 (fr) 1976-12-31
AT350518B (de) 1979-06-11
FR2313023B1 (hu) 1978-12-15
AT346826B (de) 1978-11-27
ATA612777A (de) 1978-04-15
YU94982A (en) 1982-08-31
ATA395476A (de) 1978-11-15
DE2624290A1 (de) 1977-04-14

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