FR2313023A1 - Nouveaux acides 2-amino-cycloalcane-carboxyliques, leurs derives et procede pour leur preparation - Google Patents

Nouveaux acides 2-amino-cycloalcane-carboxyliques, leurs derives et procede pour leur preparation

Info

Publication number
FR2313023A1
FR2313023A1 FR7616648A FR7616648A FR2313023A1 FR 2313023 A1 FR2313023 A1 FR 2313023A1 FR 7616648 A FR7616648 A FR 7616648A FR 7616648 A FR7616648 A FR 7616648A FR 2313023 A1 FR2313023 A1 FR 2313023A1
Authority
FR
France
Prior art keywords
aryl
aralkyl
alkyl
cpds
antiinflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7616648A
Other languages
English (en)
French (fr)
Other versions
FR2313023B1 (hu
Inventor
Gabor Bernath
Lajos Gera
Gyorgy Gondos
Kalman Kovacs
Dr Janvari
Nee Erzsebet Kanyo
Gyula Sebestyen
Zoltan Ecsery
Hermann-Nee-Judit Dr Voros
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of FR2313023A1 publication Critical patent/FR2313023A1/fr
Application granted granted Critical
Publication of FR2313023B1 publication Critical patent/FR2313023B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
FR7616648A 1975-06-02 1976-06-02 Nouveaux acides 2-amino-cycloalcane-carboxyliques, leurs derives et procede pour leur preparation Granted FR2313023A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI001580 HU177576B (en) 1975-06-02 1975-06-02 Process for preparing 2-amino-cyclohexane carboxylic acid,its amides and similar compounds

Publications (2)

Publication Number Publication Date
FR2313023A1 true FR2313023A1 (fr) 1976-12-31
FR2313023B1 FR2313023B1 (hu) 1978-12-15

Family

ID=10994566

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7616648A Granted FR2313023A1 (fr) 1975-06-02 1976-06-02 Nouveaux acides 2-amino-cycloalcane-carboxyliques, leurs derives et procede pour leur preparation

Country Status (6)

Country Link
AT (2) AT350518B (hu)
CS (1) CS217955B2 (hu)
DE (1) DE2624290A1 (hu)
FR (1) FR2313023A1 (hu)
HU (1) HU177576B (hu)
YU (2) YU129376A (hu)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0214009A2 (en) * 1985-07-30 1987-03-11 Merck & Co. Inc. Enaminones as potential prodrugs of primary and secondary amines
EP0482410A2 (de) * 1990-10-20 1992-04-29 Bayer Ag Antimikrobielle Mittel sowie substituierte 2-Cyclohexan-1-yl-amin-Derivate und deren Herstellung
EP0571870A1 (de) * 1992-05-29 1993-12-01 Bayer Ag Cyclopentan- und -penten-beta-Aminosäuren

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3125872A1 (de) * 1981-07-01 1983-01-20 Basf Ag, 6700 Ludwigshafen Schiff-basen von aminocycloalkancarbonsaeureestern, verfahren zu ihrer herstellung sowie ihre verwendung als zwischenprodukte
GB8716278D0 (en) * 1987-07-10 1987-08-19 Fujisawa Pharmaceutical Co Antimicrobial agent
US6462076B2 (en) 2000-06-14 2002-10-08 Hoffmann-La Roche Inc. Beta-amino acid nitrile derivatives as cathepsin K inhibitors
US6759428B2 (en) 2001-12-04 2004-07-06 Roche Palo Alto Llc Indole nitriles
CN1315806C (zh) 2001-12-04 2007-05-16 霍夫曼·拉罗奇有限公司 取代的2－氨基－环烷烃甲酰胺和它们作为半胱氨酸蛋白酶抑制剂的用途
WO2004056744A1 (en) * 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
EP1533295A1 (en) * 2003-11-24 2005-05-25 Newron Pharmaceuticals S.p.A. Cyclopentyl Derivatives
JP5014983B2 (ja) 2004-05-07 2012-08-29 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ １１−ベータヒドロキシステロイドデヒドロゲナーゼ阻害剤としてのピロリジン−２−オン及びピペリジン−２−オン誘導体
EP1786774B1 (en) 2004-08-30 2009-10-14 Janssen Pharmaceutica N.V. Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
NZ553159A (en) 2004-08-30 2010-05-28 Janssen Pharmaceutica Nv N-Adamantan-2-yl-2-phenoxy-acetamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
DE602005017159D1 (de) 2004-08-30 2009-11-26 Janssen Pharmaceutica Nv Oxysteroid-dehydrogenase-inhibitoren
JP5547753B2 (ja) 2009-02-17 2014-07-16 マクアリスター テクノロジーズ エルエルシー 電気分解の間にガスを捕集するための装置および方法
US8075750B2 (en) 2009-02-17 2011-12-13 Mcalister Technologies, Llc Electrolytic cell and method of use thereof
JP5411299B2 (ja) 2009-02-17 2014-02-12 マクアリスター テクノロジーズ エルエルシー 電解セルおよびその使用方法
US9040012B2 (en) 2009-02-17 2015-05-26 Mcalister Technologies, Llc System and method for renewable resource production, for example, hydrogen production by microbial electrolysis, fermentation, and/or photosynthesis
RU2489523C2 (ru) 2009-02-17 2013-08-10 МАКЭЛИСТЭР ТЕКНОЛОДЖИЗ, ЭлЭлСи Устройство и способ регулирования зародышеобразования во время электролиза

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines
US3647804A (en) * 1970-02-27 1972-03-07 Upjohn Co Cycloalkanecarboxamides
US3770825A (en) * 1970-12-07 1973-11-06 Yeda Res & Dev 2-substituted amino cycloalkylcarboxamides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines
US3647804A (en) * 1970-02-27 1972-03-07 Upjohn Co Cycloalkanecarboxamides
US3770825A (en) * 1970-12-07 1973-11-06 Yeda Res & Dev 2-substituted amino cycloalkylcarboxamides

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0214009A2 (en) * 1985-07-30 1987-03-11 Merck & Co. Inc. Enaminones as potential prodrugs of primary and secondary amines
EP0214009A3 (en) * 1985-07-30 1989-01-11 Merck & Co. Inc. Enaminones as potential prodrugs of primary and secondary amines
EP0482410A2 (de) * 1990-10-20 1992-04-29 Bayer Ag Antimikrobielle Mittel sowie substituierte 2-Cyclohexan-1-yl-amin-Derivate und deren Herstellung
EP0482410A3 (en) * 1990-10-20 1992-09-09 Bayer Ag Anti-microbial compounds, including substituted 2-cyclohexyl-amine derivatives and their preparation
EP0571870A1 (de) * 1992-05-29 1993-12-01 Bayer Ag Cyclopentan- und -penten-beta-Aminosäuren

Also Published As

Publication number Publication date
HU177576B (en) 1981-11-28
YU129376A (en) 1982-08-31
AT350518B (de) 1979-06-11
FR2313023B1 (hu) 1978-12-15
CS217955B2 (en) 1983-02-25
AT346826B (de) 1978-11-27
ATA612777A (de) 1978-04-15
YU94982A (en) 1982-08-31
ATA395476A (de) 1978-11-15
DE2624290A1 (de) 1977-04-14

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Legal Events

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