CS212304B2 - Method of making the salts of the 6,7-dihalogen-3,4-dihydro-3-oxo-chinxalin-carboxyl acids with defended amines - Google Patents

Method of making the salts of the 6,7-dihalogen-3,4-dihydro-3-oxo-chinxalin-carboxyl acids with defended amines Download PDF

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Publication number
CS212304B2
CS212304B2 CS807188A CS718880A CS212304B2 CS 212304 B2 CS212304 B2 CS 212304B2 CS 807188 A CS807188 A CS 807188A CS 718880 A CS718880 A CS 718880A CS 212304 B2 CS212304 B2 CS 212304B2
Authority
CS
Czechoslovakia
Prior art keywords
oxo
dihydro
carboxylic acid
salt
quinoxaline carboxylic
Prior art date
Application number
CS807188A
Other languages
Czech (cs)
English (en)
Inventor
Riaz F Abdulla
Donald C Delong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS212304B2 publication Critical patent/CS212304B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/76—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CS807188A 1979-10-25 1980-10-23 Method of making the salts of the 6,7-dihalogen-3,4-dihydro-3-oxo-chinxalin-carboxyl acids with defended amines CS212304B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/088,275 US4252954A (en) 1979-10-25 1979-10-25 Salts of dihalo-3,4-dihydro-3-oxo-2-quinoxaline carboxylic acids and hindered amines

Publications (1)

Publication Number Publication Date
CS212304B2 true CS212304B2 (en) 1982-03-26

Family

ID=22210429

Family Applications (1)

Application Number Title Priority Date Filing Date
CS807188A CS212304B2 (en) 1979-10-25 1980-10-23 Method of making the salts of the 6,7-dihalogen-3,4-dihydro-3-oxo-chinxalin-carboxyl acids with defended amines

Country Status (20)

Country Link
US (1) US4252954A (fr)
EP (1) EP0029658A1 (fr)
JP (1) JPS5681569A (fr)
AU (1) AU6351280A (fr)
BE (1) BE885793A (fr)
CA (1) CA1149381A (fr)
CS (1) CS212304B2 (fr)
DD (1) DD153689A5 (fr)
DK (1) DK449780A (fr)
ES (1) ES496210A0 (fr)
FI (1) FI803294L (fr)
FR (1) FR2467848A1 (fr)
GB (1) GB2061936A (fr)
GR (1) GR69994B (fr)
IL (1) IL61313A0 (fr)
IT (1) IT1134009B (fr)
PL (1) PL227421A1 (fr)
PT (1) PT71939B (fr)
YU (1) YU268880A (fr)
ZA (1) ZA806437B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD281614A5 (de) * 1988-09-02 1990-08-15 Univ Berlin Humboldt Verfahren zur herstellung von virostatisch wirksamendiazinsubstituierten 1-adamantanen
WO1992011245A1 (fr) * 1990-12-20 1992-07-09 Warner-Lambert Company Derives 2-acylamido de 3,4-dihydro-3-oxo-quinoxaline possedant une activite pharmaceutique
AU744540B2 (en) * 1997-09-01 2002-02-28 Kyorin Pharmaceutical Co. Ltd. 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid derivatives, addition salts thereof, and processes for the preparation of both
EP1608319A4 (fr) 2003-04-03 2007-02-28 Univ California Inhibiteurs ameliores pour hydrolase epoxyde soluble
JP2007532484A (ja) 2004-03-16 2007-11-15 ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア 可溶性エポキシド加水分解酵素の阻害剤およびエポキシエイコサノイドを用いて腎症を緩和する方法
CA2584342C (fr) 2004-10-20 2013-04-30 The Regents Of The University Of California Inhibiteurs ameliores de l'epoxyde hydrolase soluble
TW200808723A (en) 2006-03-13 2008-02-16 Univ California Conformationally restricted urea inhibitors of soluble epoxide hydrolase
EP2528604B1 (fr) 2010-01-29 2017-11-22 The Regents of the University of California Inhibiteurs d'acyl pipéridine d'époxyde hydrolase soluble
WO2012045280A1 (fr) * 2010-10-08 2012-04-12 Novartis Ag Sels et polymorphes d'inhibiteurs de ns3 de type sulfamide
JP6406159B2 (ja) 2015-08-04 2018-10-17 株式会社デンソー 車載表示制御装置、車載表示制御方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355355A (en) * 1965-02-05 1967-11-28 Smith Kline French Lab Antiviral cycloalkylamine compositions and method
DE1770697C3 (de) * 1967-07-06 1981-04-23 Dupher International Research B.V., Weesp 2,2-(N-Methyl-2-azatetramethylen)- -adamantan, dessen Salze, Verfahren zu deren Herstellung und Arzneimittel
GB1438349A (en) * 1973-09-13 1976-06-03 Post Office Conductor assemblies for cables
US4181724A (en) * 1978-09-11 1980-01-01 The Upjohn Company Quinoxalinone compounds useful for expanding the lumina or air passages in mammals
GR72941B (fr) * 1978-10-20 1984-01-16 Lilly Co Eli

Also Published As

Publication number Publication date
GB2061936A (en) 1981-05-20
US4252954A (en) 1981-02-24
PL227421A1 (fr) 1981-06-19
DK449780A (da) 1981-04-26
ES8205207A1 (es) 1981-10-01
IT1134009B (it) 1986-07-24
GR69994B (fr) 1982-07-23
PT71939A (en) 1980-11-01
ES496210A0 (es) 1981-10-01
EP0029658A1 (fr) 1981-06-03
FI803294L (fi) 1981-04-26
ZA806437B (en) 1982-05-26
CA1149381A (fr) 1983-07-05
FR2467848A1 (fr) 1981-04-30
YU268880A (en) 1983-02-28
IT8025538A0 (it) 1980-10-23
PT71939B (en) 1981-08-31
IL61313A0 (en) 1980-12-31
DD153689A5 (de) 1982-01-27
AU6351280A (en) 1981-04-30
BE885793A (fr) 1981-04-21
JPS5681569A (en) 1981-07-03

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