CS208733B2 - Method of making the new amines - Google Patents

Method of making the new amines Download PDF

Info

Publication number
CS208733B2
CS208733B2 CS776486A CS312080A CS208733B2 CS 208733 B2 CS208733 B2 CS 208733B2 CS 776486 A CS776486 A CS 776486A CS 312080 A CS312080 A CS 312080A CS 208733 B2 CS208733 B2 CS 208733B2
Authority
CS
Czechoslovakia
Prior art keywords
compounds
acid
phenoxy
tablets
formula
Prior art date
Application number
CS776486A
Other languages
Czech (cs)
English (en)
Inventor
Enar I Carlsson
Gustav B Samuelsson
Bo T Lundgren
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of CS208733B2 publication Critical patent/CS208733B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Epoxy Compounds (AREA)
CS776486A 1976-10-07 1977-10-06 Method of making the new amines CS208733B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7611125A SE416545B (sv) 1976-10-07 1976-10-07 Forfarande for framstellning av nya hjertaktiva 1-frnoxi-3-aminopropan-2-ol-derivat

Publications (1)

Publication Number Publication Date
CS208733B2 true CS208733B2 (en) 1981-09-15

Family

ID=20329066

Family Applications (5)

Application Number Title Priority Date Filing Date
CS776486A CS208730B2 (en) 1976-10-07 1977-10-06 Method of making the new amines
CS776486A CS208733B2 (en) 1976-10-07 1977-10-06 Method of making the new amines
CS776486A CS208734B2 (en) 1976-10-07 1977-10-06 Method of making the new amines
CS776486A CS208732B2 (en) 1976-10-07 1977-10-06 Method of making the new amines
CS776486A CS208731B2 (en) 1976-10-07 1977-10-06 Method of making the new amines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS776486A CS208730B2 (en) 1976-10-07 1977-10-06 Method of making the new amines

Family Applications After (3)

Application Number Title Priority Date Filing Date
CS776486A CS208734B2 (en) 1976-10-07 1977-10-06 Method of making the new amines
CS776486A CS208732B2 (en) 1976-10-07 1977-10-06 Method of making the new amines
CS776486A CS208731B2 (en) 1976-10-07 1977-10-06 Method of making the new amines

Country Status (22)

Country Link
JP (1) JPS5346928A (de)
AT (1) AT351509B (de)
AU (1) AU516727B2 (de)
BE (1) BE859474A (de)
CA (1) CA1093096A (de)
CH (1) CH636337A5 (de)
CS (5) CS208730B2 (de)
DD (1) DD132195A5 (de)
DE (1) DE2743493A1 (de)
DK (1) DK145375C (de)
FI (1) FI772936A (de)
FR (1) FR2367054A1 (de)
GB (1) GB1589838A (de)
HU (1) HU177638B (de)
IE (1) IE45938B1 (de)
LU (1) LU78263A1 (de)
NL (1) NL7710941A (de)
NO (1) NO145436C (de)
NZ (1) NZ185318A (de)
SE (1) SE416545B (de)
SU (3) SU735166A3 (de)
ZA (1) ZA775603B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols
GB8519154D0 (en) * 1985-07-30 1985-09-04 Ici Plc Aromatic ethers
JPH0627370B2 (ja) * 1985-08-23 1994-04-13 日本エステル株式会社 ポリエステル異形断面太細糸
GB8925032D0 (en) * 1989-11-06 1989-12-28 Ici Plc Chemical compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE590054A (fr) * 1959-04-22 1960-10-24 Pfizer Alkylamines et leur préparation.
GB1264128A (de) * 1968-06-29 1972-02-16
GB1433920A (en) * 1973-10-01 1976-04-28 Ici Ltd Alkanolamine derivatives

Also Published As

Publication number Publication date
ATA702177A (de) 1979-01-15
FR2367054A1 (fr) 1978-05-05
HU177638B (en) 1981-11-28
CA1093096A (en) 1981-01-06
AU2930077A (en) 1979-04-12
IE45938B1 (en) 1983-01-12
FI772936A (fi) 1978-04-08
JPS5346928A (en) 1978-04-27
NL7710941A (nl) 1978-04-11
CS208730B2 (en) 1981-09-15
SU735166A3 (ru) 1980-05-15
SE7611125L (sv) 1978-04-08
BE859474A (fr) 1978-04-07
FR2367054B1 (de) 1981-11-06
AU516727B2 (en) 1981-06-18
NO145436C (no) 1982-03-24
NO773406L (no) 1978-04-10
SU784760A3 (ru) 1980-11-30
CS208732B2 (en) 1981-09-15
DK145375B (da) 1982-11-08
CS208731B2 (en) 1981-09-15
LU78263A1 (de) 1978-06-09
GB1589838A (en) 1981-05-20
AT351509B (de) 1979-07-25
DK443177A (da) 1978-04-08
NZ185318A (en) 1980-02-21
DE2743493A1 (de) 1978-04-13
CS208734B2 (en) 1981-09-15
DD132195A5 (de) 1978-09-06
IE45938L (en) 1978-04-07
SU959623A3 (ru) 1982-09-15
CH636337A5 (en) 1983-05-31
ZA775603B (en) 1978-06-28
NO145436B (no) 1981-12-14
SE416545B (sv) 1981-01-19
DK145375C (da) 1983-04-11

Similar Documents

Publication Publication Date Title
BG61420B2 (bg) 3-метилов естер 5-етилов естер на 2,6-диметил-4-(2,3- дихлорофенил)-1,4-дихидропиридин-3,5-дикарбоксиловата киселина,притежаващ хипотензивни свойства,метод за неговото получаване и фармацевтични пре парати, които ги съдържат
CS196290B2 (en) Process for preparing new compounds
US4244969A (en) Heart active compounds
FI63745B (fi) Foerfarande foer framstaellning av nya terapeutiskt vaerdefulla aminer
US3925446A (en) 1-Aryloxy-2-hydroxy-3-alkynylamino-propanes
PL135700B1 (en) Process for preparing novel derivatives of benzamide
WO2017170826A1 (ja) グルカゴン様ペプチド－１受容体作用増強活性を有する化合物
CA1093095A (en) Amines
CS208733B2 (en) Method of making the new amines
CN110087729A (zh) 一类具有季铵盐结构的双功能化合物
EP0007294A2 (de) Membranstabilisierende Verbindungen mit Beta-Rezeptorenblocker-Wirkung, ihre Herstellung, Methode zur Behandlung arhythmischer Zustände und pharmazeutische Zusammensetzungen, die sie enthalten
US4263325A (en) β-Receptor blocking compounds and treatment of cardiovascular disorders therewith
JPH0633247B2 (ja) ３―アミノプロポキシフェニル誘導体およびその製法ならび用途
TW460461B (en) Substituted phenylamidines for use in fighting or preventing diseases in which smaller or larger cell aggregations occur or cell-matrix interactions are involved, pharmaceutical compositions containing these compounds and processes for preparing them
IE42131B1 (en) New aryloxy n-aralkyl propanolamines,their preparation andpharmaceutical compositions containing them
EP0064487A1 (de) Substituierte 3-(parasubstituierte) Phenoxy-1-alkylamino-2-propanole sowie Verfahren zu deren Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und Methode zur Behandlung von Herzversagen
AT363067B (de) Verfahren zur herstellung von neuen 3-phenoxy-2-hydroxy-1-phenoxy- oder -1-phenylthioalkylamino-propanen und von deren saeureadditionssalzen
US6242466B1 (en) Substituted phenylamidines
US4000313A (en) 1-Isopropylamino-3[4'-(2-methoxy- or ethoxy-carbonylaminoethoxy)-phenoxy]propanol-2 and cardioselective antagonism use
AT345790B (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1- aminopropanen und deren saeureaddtionssalzen
CN103304502B (zh) 一类抗糖尿病化合物、其制备方法和用途
US4078146A (en) Phenoxy propanolamines
JPS5852286A (ja) 新規なジヒドロピリジン化合物
AT353250B (de) Verfahren zur herstellung von neuen 3-phenoxy-2 -hydroxy-1-phenoxy- oder -1- phenylthioalkyl- amino-propanen und von deren saeureadditions- salzen
CH632987A5 (en) Process for preparing novel amines