CS203179B2 - Process for preparing derivatives of n-/benzothiazol-2-yl/oxamidic acid - Google Patents
Process for preparing derivatives of n-/benzothiazol-2-yl/oxamidic acid Download PDFInfo
- Publication number
- CS203179B2 CS203179B2 CS778173A CS817377A CS203179B2 CS 203179 B2 CS203179 B2 CS 203179B2 CS 778173 A CS778173 A CS 778173A CS 817377 A CS817377 A CS 817377A CS 203179 B2 CS203179 B2 CS 203179B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- mol
- ethyl ester
- substituents
- theory
- chloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762656468 DE2656468A1 (de) | 1976-12-14 | 1976-12-14 | N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS203179B2 true CS203179B2 (en) | 1981-02-27 |
Family
ID=5995427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS778173A CS203179B2 (en) | 1976-12-14 | 1977-12-07 | Process for preparing derivatives of n-/benzothiazol-2-yl/oxamidic acid |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5377058A (fi) |
| AR (1) | AR216496A1 (fi) |
| AT (1) | AT360523B (fi) |
| AU (1) | AU510730B2 (fi) |
| BE (1) | BE861794A (fi) |
| CS (1) | CS203179B2 (fi) |
| DD (1) | DD133329A5 (fi) |
| DE (1) | DE2656468A1 (fi) |
| ES (1) | ES465034A1 (fi) |
| FI (1) | FI57594C (fi) |
| FR (1) | FR2374317A1 (fi) |
| GB (1) | GB1538822A (fi) |
| HU (1) | HU175340B (fi) |
| NL (1) | NL7713580A (fi) |
| SE (1) | SE7714074L (fi) |
| SU (1) | SU680647A3 (fi) |
| ZA (1) | ZA777236B (fi) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2676775A (en) * | 1949-10-24 | 1954-04-27 | Gustav O Schulz | Electric flatiron cord holder |
| DE3017976A1 (de) * | 1980-05-10 | 1981-11-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | Substituierte 2-amino-5-halogen-benzothiazole, verfahen zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US4321372A (en) | 1980-06-16 | 1982-03-23 | Pfizer Inc. | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides |
| DE3027527A1 (de) | 1980-07-19 | 1982-02-18 | Basf Ag, 6700 Ludwigshafen | Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| GB2090826B (en) * | 1981-01-09 | 1985-06-12 | Usv Pharma Corp | New heterocyclic compounds useful as anti-allergie agents |
| DE3135250A1 (de) * | 1981-09-05 | 1983-03-17 | Basf Ag, 6700 Ludwigshafen | Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| US4826860A (en) * | 1987-03-16 | 1989-05-02 | Warner-Lambert Company | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents |
| FI91859C (fi) * | 1987-06-17 | 1994-08-25 | Eisai Co Ltd | Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi |
| EP1303272B1 (en) | 2000-06-21 | 2008-02-13 | F. Hoffmann-La Roche Ag | Benzothiazole derivatives for the treatment of alzheimer's disease and parkinson's disease |
| US7087761B2 (en) | 2003-01-07 | 2006-08-08 | Hoffmann-La Roche Inc. | Cyclization process for substituted benzothiazole derivatives |
| AU2005247567B2 (en) | 2004-05-24 | 2010-09-02 | F. Hoffmann-La Roche Ag | 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide |
| US7459563B2 (en) | 2004-11-05 | 2008-12-02 | Hoffmann-La Roche Inc. | Process for the preparation of isonicotinic acid derivatives |
| BRPI0609719B8 (pt) | 2005-03-23 | 2021-05-25 | Hoffmann La Roche | derivados de acetilenil-pirazol-pirimidina como antagonistas de mgbur2 |
| BRPI0616571A2 (pt) | 2005-09-27 | 2011-06-21 | Hoffmann La Roche | oxadiazolil pirazol-piridiminas como antagonistas de mglur2, processo para sua preparação, composição farmacêutica que os contém e uso dos mesmo |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4150140A (en) * | 1976-12-23 | 1979-04-17 | The Upjohn Company | Benzothiazolyl oxanic acids, esters and salts |
-
1976
- 1976-12-14 DE DE19762656468 patent/DE2656468A1/de not_active Withdrawn
-
1977
- 1977-12-03 HU HU77BO1695A patent/HU175340B/hu unknown
- 1977-12-05 ZA ZA00777236A patent/ZA777236B/xx unknown
- 1977-12-07 AR AR270289A patent/AR216496A1/es active
- 1977-12-07 SU SU772550552A patent/SU680647A3/ru active
- 1977-12-07 GB GB50911/77A patent/GB1538822A/en not_active Expired
- 1977-12-07 CS CS778173A patent/CS203179B2/cs unknown
- 1977-12-08 DD DD7700202483A patent/DD133329A5/xx unknown
- 1977-12-08 NL NL7713580A patent/NL7713580A/xx not_active Application Discontinuation
- 1977-12-08 AU AU31377/77A patent/AU510730B2/en not_active Expired
- 1977-12-12 SE SE7714074A patent/SE7714074L/xx not_active Application Discontinuation
- 1977-12-12 FI FI773738A patent/FI57594C/fi not_active IP Right Cessation
- 1977-12-13 BE BE183407A patent/BE861794A/xx unknown
- 1977-12-13 AT AT890777A patent/AT360523B/de not_active IP Right Cessation
- 1977-12-13 FR FR7737467A patent/FR2374317A1/fr active Granted
- 1977-12-14 JP JP15041777A patent/JPS5377058A/ja active Pending
- 1977-12-14 ES ES465034A patent/ES465034A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE7714074L (sv) | 1978-06-15 |
| SU680647A3 (ru) | 1979-08-15 |
| DE2656468A1 (de) | 1978-06-15 |
| BE861794A (fr) | 1978-06-13 |
| JPS5377058A (en) | 1978-07-08 |
| AT360523B (de) | 1981-01-12 |
| AU3137777A (en) | 1979-06-14 |
| AR216496A1 (es) | 1979-12-28 |
| NL7713580A (nl) | 1978-06-16 |
| ES465034A1 (es) | 1978-09-01 |
| DD133329A5 (de) | 1978-12-27 |
| ATA890777A (de) | 1980-06-15 |
| ZA777236B (en) | 1978-11-29 |
| FI57594C (fi) | 1980-09-10 |
| GB1538822A (en) | 1979-01-24 |
| FI57594B (fi) | 1980-05-30 |
| FR2374317A1 (fr) | 1978-07-13 |
| AU510730B2 (en) | 1980-07-10 |
| FI773738A (fi) | 1978-06-15 |
| FR2374317B1 (fi) | 1980-11-07 |
| HU175340B (hu) | 1980-07-28 |
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