CS200242B2 - Process for preparing inclusion complexes of derivatives prostacycline with beta-cyclodextrine - Google Patents
Process for preparing inclusion complexes of derivatives prostacycline with beta-cyclodextrine Download PDFInfo
- Publication number
- CS200242B2 CS200242B2 CS786036A CS603678A CS200242B2 CS 200242 B2 CS200242 B2 CS 200242B2 CS 786036 A CS786036 A CS 786036A CS 603678 A CS603678 A CS 603678A CS 200242 B2 CS200242 B2 CS 200242B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- prostacyclin
- beta
- cyclodextrin
- solution
- complexes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nanotechnology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU77CI1770A HU179141B (de) | 1977-09-23 | 1977-09-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS200242B2 true CS200242B2 (en) | 1980-08-29 |
Family
ID=10994670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS786036A CS200242B2 (en) | 1977-09-23 | 1978-09-18 | Process for preparing inclusion complexes of derivatives prostacycline with beta-cyclodextrine |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS5456685A (de) |
| AT (1) | AT369362B (de) |
| BE (1) | BE870646A (de) |
| CH (1) | CH637388A5 (de) |
| CS (1) | CS200242B2 (de) |
| DD (1) | DD138600A5 (de) |
| DE (1) | DE2840142A1 (de) |
| DK (1) | DK420778A (de) |
| FI (1) | FI65912C (de) |
| FR (1) | FR2404006A1 (de) |
| GB (1) | GB2006193B (de) |
| GR (1) | GR65001B (de) |
| HU (1) | HU179141B (de) |
| IL (1) | IL55569A (de) |
| IT (1) | IT1160661B (de) |
| NL (1) | NL7809643A (de) |
| PL (1) | PL121664B1 (de) |
| SE (1) | SE447574B (de) |
| SU (1) | SU847914A3 (de) |
| YU (1) | YU220678A (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53136513A (en) * | 1977-05-06 | 1978-11-29 | Ono Pharmaceut Co Ltd | Stabilization of prostaglandin-x-related compounds |
| US4352793A (en) * | 1979-04-26 | 1982-10-05 | Sumitomo Chemical Company, Limited | Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin |
| JPS5920230A (ja) * | 1982-07-19 | 1984-02-01 | チバ−ガイギ−・アクチエンゲゼルシヤフト | ピルプロフエン含有薬剤 |
| JPS61289034A (ja) * | 1985-06-17 | 1986-12-19 | Teijin Ltd | イソカルバサイクリン類脂肪乳剤 |
| DE3608088C2 (de) * | 1986-03-07 | 1995-11-16 | Schering Ag | Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten |
| DE3740838A1 (de) * | 1987-11-27 | 1989-06-08 | Schering Ag | Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel |
| EP1710244A4 (de) * | 2004-01-29 | 2009-06-17 | Eisai R&D Man Co Ltd | Verfahren zur stabilisierung einer makrolidverbidnung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS503362B1 (de) * | 1970-06-10 | 1975-02-04 | ||
| US3953435A (en) * | 1974-01-10 | 1976-04-27 | Ono Pharmaceutical Company | Aldehyde derivatives of prostaglandins |
| JPS5395958A (en) * | 1977-01-31 | 1978-08-22 | Ono Pharmaceut Co Ltd | Prostaglandin analogues and process for their preparation |
| US4178367A (en) * | 1977-02-21 | 1979-12-11 | Ono Pharmaceutical Co. Ltd. | Prostaglandin I2 analogues |
| JPS53136513A (en) * | 1977-05-06 | 1978-11-29 | Ono Pharmaceut Co Ltd | Stabilization of prostaglandin-x-related compounds |
-
1977
- 1977-09-23 HU HU77CI1770A patent/HU179141B/hu not_active IP Right Cessation
-
1978
- 1978-09-13 GR GR57216A patent/GR65001B/el unknown
- 1978-09-13 IL IL55569A patent/IL55569A/xx unknown
- 1978-09-15 DE DE19782840142 patent/DE2840142A1/de not_active Ceased
- 1978-09-18 CS CS786036A patent/CS200242B2/cs unknown
- 1978-09-19 IT IT69160/78A patent/IT1160661B/it active
- 1978-09-19 YU YU02206/78A patent/YU220678A/xx unknown
- 1978-09-20 AT AT0677478A patent/AT369362B/de not_active IP Right Cessation
- 1978-09-21 SE SE7809946A patent/SE447574B/sv not_active IP Right Cessation
- 1978-09-21 BE BE190613A patent/BE870646A/xx not_active IP Right Cessation
- 1978-09-21 FI FI782878A patent/FI65912C/fi not_active IP Right Cessation
- 1978-09-21 DD DD78208003A patent/DD138600A5/de unknown
- 1978-09-21 FR FR7827079A patent/FR2404006A1/fr active Granted
- 1978-09-22 JP JP11738378A patent/JPS5456685A/ja active Pending
- 1978-09-22 SU SU782668853A patent/SU847914A3/ru active
- 1978-09-22 GB GB7837834A patent/GB2006193B/en not_active Expired
- 1978-09-22 DK DK420778A patent/DK420778A/da not_active Application Discontinuation
- 1978-09-22 PL PL1978209773A patent/PL121664B1/pl unknown
- 1978-09-22 CH CH995078A patent/CH637388A5/de not_active IP Right Cessation
- 1978-09-22 NL NL7809643A patent/NL7809643A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB2006193A (en) | 1979-05-02 |
| CH637388A5 (de) | 1983-07-29 |
| FI65912C (fi) | 1984-08-10 |
| FI782878A (fi) | 1979-03-24 |
| IL55569A (en) | 1981-12-31 |
| PL209773A1 (pl) | 1979-06-04 |
| IL55569A0 (en) | 1978-12-17 |
| SU847914A3 (ru) | 1981-07-15 |
| NL7809643A (nl) | 1979-03-27 |
| PL121664B1 (en) | 1982-05-31 |
| DE2840142A1 (de) | 1979-04-05 |
| JPS5456685A (en) | 1979-05-07 |
| YU220678A (en) | 1983-10-31 |
| HU179141B (de) | 1982-08-28 |
| SE7809946L (sv) | 1979-03-24 |
| AT369362B (de) | 1982-12-27 |
| BE870646A (fr) | 1979-01-15 |
| IT1160661B (it) | 1987-03-11 |
| FR2404006A1 (fr) | 1979-04-20 |
| GR65001B (en) | 1980-06-12 |
| ATA677478A (de) | 1982-05-15 |
| FI65912B (fi) | 1984-04-30 |
| IT7869160A0 (it) | 1978-09-19 |
| DD138600A5 (de) | 1979-11-14 |
| SE447574B (sv) | 1986-11-24 |
| GB2006193B (en) | 1982-05-26 |
| DK420778A (da) | 1979-03-24 |
| FR2404006B1 (de) | 1981-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4054736A (en) | Clathrate compounds of prostaglandins or their analogues with cyclodextrin | |
| Fitzgerald et al. | Coronary vascular occlusion mediated via thromboxane A2-prostaglandin endoperoxide receptor activation in vivo. | |
| KR0125931B1 (ko) | 기관내 허혈병의 치료용 조성물 | |
| KR860009032A (ko) | γ-사이클로 덱스트린 유도체의 제조방법 | |
| NO134373B (de) | ||
| EP0032556A1 (de) | Rosmarinsäure-Phospholipid Komplexe, Verfahren zur ihrer Herstellung und sie enthaltende Arzneimittel | |
| CS200242B2 (en) | Process for preparing inclusion complexes of derivatives prostacycline with beta-cyclodextrine | |
| NO179175B (no) | Fremgangsmåte for fremstilling av kodeinsaltet av en substituert karboksylsyre | |
| US4623641A (en) | Method of treating ulcers and erosions in the gastrointestinal system using PGI2 -methyl ester-beta cyclodextrin inclusion complexes | |
| DE2720999C2 (de) | Postacyclin (bzw. (5Z)-5,6-Didehydro-9-desoxy-6,9α-epoxyprostaglandin F↓1↓↓α↓), Verfahren zu dessen Herstellung und diese Verbindung enthaltende pharmazeutische Formulierungen | |
| US5166200A (en) | Treatment of endometriosis | |
| US4675182A (en) | Complexes of prostaglandins | |
| DE69122122T2 (de) | Hydroxamsäuren zur prävention von peperfusionsschäden | |
| JPH07157431A (ja) | 安定なプロスタグランジンｅ製剤 | |
| FR2528846A1 (fr) | Nouveau derive de la pyrazolo (1,5-a) pyridine, sa preparation et les compositions pharmaceutiques qui le contiennent | |
| EP0444199A1 (de) | Ascorbinsäure-derivate | |
| JPS61178967A (ja) | 新規なチオスルフオネ−ト誘導体、該誘導体の製造法、及び該誘導体を含有する薬理組成物 | |
| EP0255141B1 (de) | Wirkstoffkombination enthaltend Diltiazem und Acetylsalicylsäure, deren Herstellung sowie deren Verwendung zur Herstellung von Arzneimitteln mit einer die Thrombozyten-aggregation hemmenden Wirkung | |
| WO1994001422A1 (en) | Pharmaceutical compositions having antiaggregant and vasodilating activities | |
| DE3019885C2 (de) | ||
| JPS62294616A (ja) | 抗真菌用薬剤 | |
| JPH0250086B2 (de) | ||
| EP0254068B1 (de) | Therapeutisches Mittel für Gastritis | |
| US4959394A (en) | Novel Guanidinium aspartates | |
| US4093719A (en) | Antiarthritic compositions comprising bis[(trialkyl-phosphine)gold(I)]sulfides and methods of producing antiarthritic activity |