CS195677B2 - Method of producing new derivatives of alkyl-n-acyl-6,7-aziridino-6-deamino-7-deoxy-alfa-thiolincosaminide - Google Patents

Method of producing new derivatives of alkyl-n-acyl-6,7-aziridino-6-deamino-7-deoxy-alfa-thiolincosaminide Download PDF

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Publication number
CS195677B2
CS195677B2 CS741577A CS157774A CS195677B2 CS 195677 B2 CS195677 B2 CS 195677B2 CS 741577 A CS741577 A CS 741577A CS 157774 A CS157774 A CS 157774A CS 195677 B2 CS195677 B2 CS 195677B2
Authority
CS
Czechoslovakia
Prior art keywords
deoxy
alkyl
formula
hydrogen
acyl
Prior art date
Application number
CS741577A
Other languages
Czech (cs)
English (en)
Inventor
Brian Bannister
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CS195677B2 publication Critical patent/CS195677B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16—Lincomycin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
CS741577A 1973-03-06 1974-03-05 Method of producing new derivatives of alkyl-n-acyl-6,7-aziridino-6-deamino-7-deoxy-alfa-thiolincosaminide CS195677B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US338459A US3870699A (en) 1973-03-06 1973-03-06 Lincomycin analogs

Publications (1)

Publication Number Publication Date
CS195677B2 true CS195677B2 (en) 1980-02-29

Family

ID=23324898

Family Applications (1)

Application Number Title Priority Date Filing Date
CS741577A CS195677B2 (en) 1973-03-06 1974-03-05 Method of producing new derivatives of alkyl-n-acyl-6,7-aziridino-6-deamino-7-deoxy-alfa-thiolincosaminide

Country Status (15)

Country Link
US (2) US3870699A (fr)
JP (1) JPS5857439B2 (fr)
BE (1) BE811931A (fr)
CA (1) CA1020938A (fr)
CH (1) CH617440A5 (fr)
CS (1) CS195677B2 (fr)
FR (1) FR2220252B1 (fr)
GB (1) GB1447462A (fr)
HU (2) HU170910B (fr)
NL (1) NL7402239A (fr)
PL (4) PL101373B1 (fr)
SE (2) SE420098B (fr)
SU (1) SU944506A3 (fr)
YU (1) YU36744B (fr)
ZA (1) ZA74935B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01280176A (ja) * 1988-04-30 1989-11-10 Sekisui Plastics Co Ltd コンクリート構造物の孔あけ方法
CA2458644A1 (fr) * 2001-08-28 2003-03-13 Pharmacia Corporation Clindamycine cristalline sous forme de base libre
US7199105B2 (en) * 2002-08-15 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
EP1529052A2 (fr) * 2002-08-15 2005-05-11 Vicuron Pharmaceuticals, Inc. Derives de lincomycine presentant une activite antibacterienne
US7199106B2 (en) 2003-06-17 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antimicrobial activity
US7256177B2 (en) 2003-06-17 2007-08-14 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
US7361743B2 (en) * 2004-02-11 2008-04-22 Pfizer Inc Lincomycin derivatives possessing antibacterial activity
JP5064237B2 (ja) 2005-12-09 2012-10-31 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 リンコマイシン誘導体およびこれを有効成分とする抗菌剤
TWI499414B (zh) * 2006-09-29 2015-09-11 Lexicon Pharmaceuticals Inc 鈉與葡萄糖第２型共同運輸體（ｃｏ-ｔｒａｎｓｐｏｒｔｅｒ ２）的抑制物與其應用方法
US7867980B2 (en) * 2007-05-31 2011-01-11 Meiji Seika Kaisha, Ltd. Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient
US7879808B2 (en) * 2007-05-31 2011-02-01 Meiji Seika Kaisha, Ltd. Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient
TWI472521B (zh) * 2008-07-17 2015-02-11 Lexicon Pharmaceuticals Inc （２ｓ，３ｒ，４ｒ，５ｓ，６ｒ）－２－（４－氯－３－（４－乙氧苄基）苯基）－６－（甲硫）四氫－２ｈ－哌喃－３，４，５－三醇的固體形態與其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271385A (en) * 1964-04-13 1966-09-06 Upjohn Co Carbamoyl derivatives of lincomycin and processes for producing them
US3702322A (en) * 1970-04-06 1972-11-07 Upjohn Co Derivatives of lincomycin and its analogs and process
US3689474A (en) * 1970-08-04 1972-09-05 Upjohn Co 7-mercapto-7-deoxylincomycins and process for preparing the same

Also Published As

Publication number Publication date
NL7402239A (fr) 1974-09-10
PL102863B1 (pl) 1979-04-30
SE435625B (sv) 1984-10-08
PL102355B1 (pl) 1979-03-31
CH617440A5 (fr) 1980-05-30
JPS5857439B2 (ja) 1983-12-20
SU944506A3 (ru) 1982-07-15
USRE29558E (en) 1978-02-28
BE811931A (fr) 1974-09-06
FR2220252A1 (fr) 1974-10-04
PL101373B1 (pl) 1978-12-30
JPS49134617A (fr) 1974-12-25
CA1020938A (fr) 1977-11-15
SE7712151L (sv) 1977-10-27
YU36744B (en) 1984-08-31
HU170910B (hu) 1977-09-28
US3870699A (en) 1975-03-11
HU170525B (fr) 1977-06-28
FR2220252B1 (fr) 1977-11-10
PL102862B1 (pl) 1979-04-30
GB1447462A (en) 1976-08-25
SE420098B (sv) 1981-09-14
AU6569774A (en) 1975-08-21
YU58274A (en) 1982-02-25
ZA74935B (en) 1974-12-24

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