CS182787A2 - Method of ibuprophen granules preparation - Google Patents

Method of ibuprophen granules preparation Download PDF

Info

Publication number
CS182787A2
CS182787A2 CS871827A CS182787A CS182787A2 CS 182787 A2 CS182787 A2 CS 182787A2 CS 871827 A CS871827 A CS 871827A CS 182787 A CS182787 A CS 182787A CS 182787 A2 CS182787 A2 CS 182787A2
Authority
CS
Czechoslovakia
Prior art keywords
ibuprofen
granules
crystalline
weight
rollers
Prior art date
Application number
CS871827A
Other languages
Czech (cs)
English (en)
Inventor
Keith Gb Allan
David Wesley Us Bogan
Jivn-Ren Us Chen
Richard Michael Gb Slater
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of CS182787A2 publication Critical patent/CS182787A2/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CS871827A 1986-03-19 1987-03-18 Method of ibuprophen granules preparation CS182787A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868606762A GB8606762D0 (en) 1986-03-19 1986-03-19 Therapeutic agents

Publications (1)

Publication Number Publication Date
CS182787A2 true CS182787A2 (en) 1991-05-14

Family

ID=10594868

Family Applications (1)

Application Number Title Priority Date Filing Date
CS871827A CS182787A2 (en) 1986-03-19 1987-03-18 Method of ibuprophen granules preparation

Country Status (21)

Country Link
EP (1) EP0241126B1 (it)
JP (1) JPS62230723A (it)
KR (1) KR870008582A (it)
CN (1) CN87101974A (it)
AT (1) ATE65393T1 (it)
AU (1) AU7017787A (it)
CS (1) CS182787A2 (it)
DD (1) DD263232A5 (it)
DE (1) DE3771544D1 (it)
DK (1) DK136487A (it)
FI (1) FI871112A (it)
GB (2) GB8606762D0 (it)
HU (1) HU195422B (it)
IL (1) IL81884A0 (it)
IN (1) IN163939B (it)
NO (1) NO871120L (it)
NZ (1) NZ219560A (it)
PL (1) PL264695A1 (it)
PT (1) PT84526B (it)
YU (1) YU47087A (it)
ZA (1) ZA871836B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3833448A1 (de) * 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
CA2063141C (en) * 1989-08-04 1997-03-04 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
WO1993013756A1 (en) * 1992-01-10 1993-07-22 Obschestvo S Ogranichennoy Otvetstvennostyu Meditsinsky Nauchno-Proizvodstvennoy Komplex 'biotiki' Granulated pharmaceutical composition and method of obtaining it
EP0721331B1 (en) * 1993-10-01 2001-12-05 AstraZeneca AB Process i
IS1736B (is) * 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
FR2804603B1 (fr) * 2000-02-04 2004-01-23 Rhodia Chimie Sa Procede continu pour formuler sous forme de granules une ou plusieurs matieres actives pharmaceutiques
DE102005037630A1 (de) 2005-08-09 2007-02-15 Glatt Gmbh Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung
KR102237799B1 (ko) 2012-11-14 2021-04-08 더블유.알. 그레이스 앤드 캄파니-콘. 생물학적 활성 물질 및 비-정렬된 무기 산화물을 함유하는 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
JPS60120616A (ja) * 1983-12-05 1985-06-28 Yaskawa Electric Mfg Co Ltd プリセット型可逆カウンタ装置
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing

Also Published As

Publication number Publication date
KR870008582A (ko) 1987-10-19
NZ219560A (en) 1989-05-29
GB2187952A (en) 1987-09-23
DK136487D0 (da) 1987-03-17
GB8704987D0 (en) 1987-04-08
GB8606762D0 (en) 1986-04-23
EP0241126B1 (en) 1991-07-24
ZA871836B (en) 1987-09-02
ATE65393T1 (de) 1991-08-15
GB2187952B (en) 1990-05-09
DE3771544D1 (de) 1991-08-29
AU7017787A (en) 1987-09-24
EP0241126A1 (en) 1987-10-14
CN87101974A (zh) 1987-10-21
DK136487A (da) 1987-09-20
IL81884A0 (en) 1987-10-20
FI871112A (fi) 1987-09-20
YU47087A (en) 1988-04-30
PT84526A (en) 1987-04-01
PL264695A1 (en) 1988-05-12
JPS62230723A (ja) 1987-10-09
PT84526B (pt) 1989-11-10
NO871120L (no) 1987-09-21
HUT42939A (en) 1987-09-28
FI871112A0 (fi) 1987-03-13
NO871120D0 (no) 1987-03-18
IN163939B (it) 1988-12-10
HU195422B (en) 1988-05-30
DD263232A5 (de) 1988-12-28

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