CS144891A3 - Novel bicyclic 1-azacycloalkanes - Google Patents

Novel bicyclic 1-azacycloalkanes

Info

Publication number
CS144891A3
CS144891A3 CS911448A CS144891A CS144891A3 CS 144891 A3 CS144891 A3 CS 144891A3 CS 911448 A CS911448 A CS 911448A CS 144891 A CS144891 A CS 144891A CS 144891 A3 CS144891 A3 CS 144891A3
Authority
CS
Czechoslovakia
Prior art keywords
azacycloalkanes
novel bicyclic
bicyclic
novel
Prior art date
Application number
CS911448A
Other languages
English (en)
Inventor
Gerhard Dr Walther
Ulrike Dr Kufner-Muhl
Werner Dr Stransky
Karl-Heinz Dr Weber
Helmut Dr Ensinger
Franz Josef Dr Kuhn
Enzio Prof Dr Muller
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of CS144891A3 publication Critical patent/CS144891A3/cs
Publication of CZ281837B6 publication Critical patent/CZ281837B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
CS911448A 1990-05-19 1991-05-16 Nové bicyklické 1-azacykloalkany CZ281837B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4016212 1990-05-19
DE4018886 1990-06-13

Publications (2)

Publication Number Publication Date
CS144891A3 true CS144891A3 (en) 1992-05-13
CZ281837B6 CZ281837B6 (cs) 1997-02-12

Family

ID=25893382

Country Status (14)

Country Link
EP (1) EP0458214A1 (cs)
JP (1) JP2853837B2 (cs)
KR (1) KR910020009A (cs)
AU (1) AU648789B2 (cs)
CA (1) CA2042860A1 (cs)
CZ (1) CZ281837B6 (cs)
FI (1) FI912409A (cs)
HU (1) HUT58091A (cs)
IE (1) IE911688A1 (cs)
IL (1) IL98176A0 (cs)
NO (1) NO911934L (cs)
PT (1) PT97703A (cs)
SK (1) SK279168B6 (cs)
YU (1) YU84791A (cs)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU215832B (hu) * 1990-05-11 1999-04-28 Sankyo Co., Ltd. Eljárás piperidil-oxi- és kinuklidinil-oxi-izoxazol-származékok, és ilyen vegyületeket tartalmazó gyógyászati készítmények előállítására
GB9122988D0 (en) * 1991-10-30 1991-12-18 Ici Plc Heterocyclic compounds
GB9127279D0 (en) * 1991-12-23 1992-02-19 Ici Plc Heterocyclic derivatives
EP0596058A1 (en) * 1992-04-10 1994-05-11 Zeneca Limited Biphenylylquinuclidine derivatives as squalene synthase inhibitors
GB9211796D0 (en) * 1992-06-04 1992-07-15 Ici Plc Heterocyclic derivatives
IT1255179B (it) * 1992-06-26 1995-10-20 Enzo Cereda Azaciclo e azabiciclo alchiliden idrossilamine
GB9216721D0 (en) * 1992-08-06 1992-09-23 Ici Plc Therapeutic heterocyclic derivatives
GB9218334D0 (en) * 1992-08-28 1992-10-14 Ici Plc Heterocyclic compounds
IL107184A (en) * 1992-10-09 1997-08-14 Abbott Lab Heterocyclic ether compounds that enhance cognitive function
DE4236331A1 (de) * 1992-10-28 1994-05-05 Boehringer Ingelheim Kg Synergistische Kombination
GB9226573D0 (en) * 1992-12-21 1993-02-17 Ici Plc Heterocyclic compounds
IL109451A0 (en) * 1993-04-29 1994-07-31 Zeneca Ltd Heterocyclic derivatives
US5998404A (en) * 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5512574A (en) * 1994-12-21 1996-04-30 American Home Products Corporation Quinuclidine and azabicyclo 2.2.1! heptane pyrazinyl ethers as muscarinic agonists
US5859004A (en) * 1995-02-17 1999-01-12 Novo Nordisk A/S Use of heterocyclic compounds for the treatment of conditions caused by malfunctioning of the nicotinic cholinergic system
US6040442A (en) * 1995-06-01 2000-03-21 Eli Lilly And Company Process for preparing 1,2,5-thiadiazole containing ethers
AU1128297A (en) * 1995-12-06 1997-06-27 Eli Lilly And Company Composition for treating pain
EP0912183A4 (en) * 1996-04-23 1999-08-04 Lilly Co Eli HETEROCYCLIC COMPOSITIONS
RU2323217C2 (ru) * 2002-08-14 2008-04-27 Ньюросерч А/С Новые хинуклидиновые производные и их применение
GB0220581D0 (en) * 2002-09-04 2002-10-09 Novartis Ag Organic Compound
DE602004031124D1 (de) 2003-08-13 2011-03-03 Neurosearch As Neue chinuklidinderivative und deren pharmazeutische verwendung
US7160876B2 (en) 2003-12-22 2007-01-09 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
US20050137203A1 (en) * 2003-12-22 2005-06-23 Jianguo Ji 3-quinuclidinyl amino-substituted biaryl derivatives
US7655657B2 (en) 2003-12-22 2010-02-02 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
PE20060437A1 (es) 2004-06-18 2006-06-08 Novartis Ag COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
JP2008523058A (ja) * 2004-12-10 2008-07-03 アボット・ラボラトリーズ 縮合ビシクロ複素環置換キヌクリジン誘導体
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
TWI794742B (zh) 2020-02-18 2023-03-01 美商基利科學股份有限公司 抗病毒化合物
WO2022221514A1 (en) 2021-04-16 2022-10-20 Gilead Sciences, Inc. Methods of preparing carbanucleosides using amides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE321933B (cs) * 1967-10-05 1970-03-23 Astra Ab
FR2014831A1 (en) * 1968-08-01 1970-04-24 Sogeras Quinuclidinyl and quinuclidinylalkyl ethers with cholino - lytic, antihistaminic and neurosedative activity
GB8615785D0 (en) * 1986-06-27 1986-08-06 Beecham Group Plc Compounds
DE3854932T2 (de) * 1987-04-15 1996-06-13 Beecham Group Plc Am Brückenkopf substituierte Azabicyclenderivate
GB8718445D0 (en) * 1987-08-04 1987-09-09 Wyeth John & Brother Ltd Pyridyl-ethers
CA1307790C (en) * 1987-08-04 1992-09-22 Ian Anthony Cliffe Ethers
DE8817121U1 (cs) * 1988-11-22 1993-02-04 Boehringer Ingelheim Kg, 6507 Ingelheim, De

Also Published As

Publication number Publication date
IE911688A1 (en) 1991-11-20
FI912409A (fi) 1991-11-20
PT97703A (pt) 1992-02-28
CA2042860A1 (en) 1991-11-20
SK279168B6 (sk) 1998-07-08
JP2853837B2 (ja) 1999-02-03
AU648789B2 (en) 1994-05-05
IL98176A0 (en) 1992-06-21
HU911663D0 (en) 1991-11-28
JPH04226981A (ja) 1992-08-17
KR910020009A (ko) 1991-12-19
FI912409A0 (fi) 1991-05-17
NO911934D0 (no) 1991-05-16
AU7713091A (en) 1991-11-21
EP0458214A1 (de) 1991-11-27
HUT58091A (en) 1992-01-28
CZ281837B6 (cs) 1997-02-12
YU84791A (sh) 1994-06-10
NO911934L (no) 1991-11-20

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20000516