DE602004031124D1 - Neue chinuklidinderivative und deren pharmazeutische verwendung - Google Patents

Neue chinuklidinderivative und deren pharmazeutische verwendung

Info

Publication number
DE602004031124D1
DE602004031124D1 DE602004031124T DE602004031124T DE602004031124D1 DE 602004031124 D1 DE602004031124 D1 DE 602004031124D1 DE 602004031124 T DE602004031124 T DE 602004031124T DE 602004031124 T DE602004031124 T DE 602004031124T DE 602004031124 D1 DE602004031124 D1 DE 602004031124D1
Authority
DE
Germany
Prior art keywords
diseases
disorders
new
pharmaceutical use
nervous system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004031124T
Other languages
English (en)
Inventor
Dan Peters
Gunnar M Olsen
Elsebet Ostergaard Nielsen
Philip K Ahring
Tino Dyhring Jorgensen
Michael R Schrimpf
Kevin B Sippy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Abbott Laboratories
Original Assignee
Neurosearch AS
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2003/000538 external-priority patent/WO2004016608A1/en
Application filed by Neurosearch AS, Abbott Laboratories filed Critical Neurosearch AS
Publication of DE602004031124D1 publication Critical patent/DE602004031124D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
DE602004031124T 2003-08-13 2004-06-29 Neue chinuklidinderivative und deren pharmazeutische verwendung Active DE602004031124D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/DK2003/000538 WO2004016608A1 (en) 2002-08-14 2003-08-13 Novel quinuclidine derivatives and their use
PCT/EP2004/051283 WO2005016923A1 (en) 2003-08-13 2004-06-29 Novel quinuclidine derivatives and their pharmaceutical use

Publications (1)

Publication Number Publication Date
DE602004031124D1 true DE602004031124D1 (de) 2011-03-03

Family

ID=34178319

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004031124T Active DE602004031124D1 (de) 2003-08-13 2004-06-29 Neue chinuklidinderivative und deren pharmazeutische verwendung

Country Status (5)

Country Link
US (1) US7750022B2 (de)
EP (1) EP1656375B1 (de)
AT (1) ATE496050T1 (de)
DE (1) DE602004031124D1 (de)
WO (1) WO2005016923A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6612874B2 (ja) 2014-12-16 2019-11-27 アクソファント サイエンシーズ ゲーエムベーハー α７−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換キヌクリジンアミド化合物
US10370370B2 (en) 2015-06-10 2019-08-06 Axovant Sciences Gmbh Aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors
US10428062B2 (en) 2015-08-12 2019-10-01 Axovant Sciences Gmbh Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU84791A (sh) 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklicni 1-aza-cikloalkalni
AU8405991A (en) 1990-08-31 1992-03-30 Nippon Shinyaku Co. Ltd. Pyrimidine derivative and medicine
ZA92278B (en) 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
GB9201749D0 (en) 1992-01-28 1992-03-11 Smithkline Beecham Plc Medicaments
US5948793A (en) 1992-10-09 1999-09-07 Abbott Laboratories 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release
US5929247A (en) 1994-10-24 1999-07-27 Eli Lilly And Company Heterocyclic compounds and their preparation and use
US5998404A (en) 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
JPH08134067A (ja) 1994-11-11 1996-05-28 Yamanouchi Pharmaceut Co Ltd キヌクリジン誘導体
US5512574A (en) 1994-12-21 1996-04-30 American Home Products Corporation Quinuclidine and azabicyclo 2.2.1! heptane pyrazinyl ethers as muscarinic agonists
WO1997017955A1 (en) 1995-11-13 1997-05-22 Eli Lilly And Company Method for treating anxiety
US5763457A (en) 1995-11-13 1998-06-09 Eli Lilly And Company Method for treating anxiety
US5852037A (en) 1995-11-13 1998-12-22 Eli Lilly And Company Method for treating anxiety
AU1128297A (en) 1995-12-06 1997-06-27 Eli Lilly And Company Composition for treating pain
FR2754261B1 (fr) 1996-10-08 1998-10-30 Synthelabo Derives de quinuclidine, leur preparation et leur application en therapeutique
WO1998027983A1 (en) 1996-12-20 1998-07-02 Novo Nordisk A/S A method of treating hypercholesterolemia and related disorders
FR2772378B1 (fr) 1997-12-12 2000-02-04 Synthelabo Derives d'imidazole, leur preparation et leur application en therapeutique
US6953855B2 (en) 1998-12-11 2005-10-11 Targacept, Inc. 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
DE10045112A1 (de) 2000-09-11 2002-03-21 Merck Patent Gmbh Verwendung von Indolderivaten zur Behandlung von Erkrankungen des zentralen Nervensystems
US6884807B2 (en) 2000-12-01 2005-04-26 Neurosearch, A/S 3-substituted quinuclidines and their use as nicotinic agonists
JP2005511574A (ja) 2001-10-26 2005-04-28 ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー Ｎａｃｈｒアゴニストとしてのｎ−アザビシクロ−置換ヘテロ二環式カルボキサミド
US6919359B2 (en) 2001-11-08 2005-07-19 Pfizer Inc Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
BR0214016A (pt) 2001-11-09 2004-10-13 Upjohn Co Compostos azabicìclico-fenil-fundido heterocìclicos e seu uso como ligandos alfa 7 nachr
DE10156719A1 (de) 2001-11-19 2003-05-28 Bayer Ag Heteroarylcarbonsäureamide
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
AU2003210730A1 (en) 2002-02-15 2003-09-09 Pharmacia And Upjohn Company Azabicyclo-substituted benzoylamides and thioamides for treatment of cns-related disorders
CA2476624A1 (en) 2002-02-19 2003-08-28 Pharmacia & Upjohn Company Azabicyclic compounds for the treatment of disease
JP2005523288A (ja) 2002-02-19 2005-08-04 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 疾病治療用の縮合した二環式−ｎ−架橋−複素環式芳香族カルボキサミド
US7001900B2 (en) 2002-02-20 2006-02-21 Pfizer Inc. Azabicyclic compounds for the treatment of disease
CA2488761C (en) 2002-06-10 2011-05-31 Bayer Healthcare Ag 2-benzofuryl or benzothiophenyl-quinuclidinyl amides as nicotinic acetylcholine receptor inhibitors
MXPA05001702A (es) * 2002-08-14 2005-04-19 Neurosearch As Derivados de quinuclidina novedosos y su uso.
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
US20050171079A1 (en) * 2004-02-04 2005-08-04 Schrimpf Michael R. Amino-substituted tricyclic derivatives and methods of use

Also Published As

Publication number Publication date
ATE496050T1 (de) 2011-02-15
WO2005016923A1 (en) 2005-02-24
EP1656375A1 (de) 2006-05-17
EP1656375B1 (de) 2011-01-19
US20060217415A1 (en) 2006-09-28
US7750022B2 (en) 2010-07-06

Similar Documents

Publication Publication Date Title
DE60318860D1 (de) Chinucledin - derivate und deren verwendung
ATE437880T1 (de) Dimere azacyclische verbindungen und deren verwendung
ATE385497T1 (de) 3-substituierte quinuclidin-derivate und deren verwendung als nikotinischen agonisten
ATE477253T1 (de) Neuartige oxadiazol-derivate und deren medizinische verwendung
DK1551835T3 (da) Hidtil ukendte 1,4-diazabicycloalkanderivater, deres fremstilling og anvendelse
NO20085398L (no) Nye 1,4-diazabisyklo[3.2 2]nonyloksadiazolylderivater og deres medisinske anvendelse
ATE287888T1 (de) Aryl- und heteroaryldiazabicycloalkane, deren zubereitung und verwendung
ATE493415T1 (de) Neue diazabizyklische arylderivate und medizinische verwendung dafür
ATE481407T1 (de) Neue diazabicyclische arylderivate und medizinische verwendung dafür
DE60310548D1 (de) Diazabicyclische biarylderivate
DE60215172D1 (de) Neue verbindungen, deren herstellung und verwendung
BRPI0407216A (pt) Derivado de arila diazabicìclica, composição farmacêutica, uso de um derivado de arila diazabicìclica, e, método de tratamento, prevenção ou alìvio de uma doença ou um distúrbio ou uma condição
DE60307102D1 (de) 3-substituierte chinuklidine und deren verwendung
ATE401334T1 (de) Neue azacyclische ethinylderivate
DE602004031124D1 (de) Neue chinuklidinderivative und deren pharmazeutische verwendung
ATE460416T1 (de) Neuartige 1,4-diazabicycloä3.2.2ünonan-derivate und deren medizinische verwendung
MX2007004245A (es) Nuevos derivados de arilo azabiciclicos y su uso medico.